Pre-operative Versus Post-operative Vaginal Cleansing With Chlorhexidine Solution in Prevention Post-Cesarean Section Infection
NCT ID: NCT06176573
Last Updated: 2023-12-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
120 participants
INTERVENTIONAL
2021-04-01
2021-08-31
Brief Summary
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Detailed Description
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Aim: To compare the effectiveness of preoperative vaginal cleansing with immediate postoperative vaginal cleansing with chlorhexidine solution in preventing post-cesarean infectious morbidities.
Method: Randomized trial involving 120 consented women who had elective or emergency cesarean sections at term, 60 in each group. Group 1 had preoperative while group 2 had postoperative vaginal cleansing with 1% chlorhexidine. Research Randomizer software was used to generate 120 numbers. Sixty numbers were randomly generated from a pool of 120 numbers and were assigned to group 1 while the remaining 60 numbers were automatically assigned to group 2. Both groups received antibiotics and anterior abdominal wall scrubbing. There were monitored for symptoms and signs of endometritis, wound infection and pyrexia till discharge.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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First arm - Pre-operative vaginal cleansing with chlorhexidine
Had vaginal cleansing with chlorhexidine prior to cesarean section and were monitored for infectious morbidity.
Chlorhexidine
Pre-operative and post-operative vaginal cleansing.
Second arm - Post-operative vaginal cleansing with chlorhexidine
Had vaginal cleansing with chlorhexidine after cesarean section and were monitored for infectious morbidity.
Chlorhexidine
Pre-operative and post-operative vaginal cleansing.
Interventions
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Chlorhexidine
Pre-operative and post-operative vaginal cleansing.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Term pregnancy
Exclusion Criteria
* Antepartum hemorrhage
* Cord prolapse
* Fetal distress
* Anemia in pregnancy
* Presence of fever and chorioamnionitis
18 Years
44 Years
FEMALE
No
Sponsors
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Federal Teaching Hospital Abakaliki
OTHER_GOV
Responsible Party
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Nwali Matthew Igwe
Principal Investigator
Locations
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Alex Ekwueme Federal University Teaching Hospital
Abakaliki, Ebonyi State, Nigeria
Countries
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Other Identifiers
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PVPVC2023CT
Identifier Type: -
Identifier Source: org_study_id