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Correlation Between Popliteal Vein Compliance and Venous Clinical Severity Score

NCT ID: NCT06175481

Last Updated: 2023-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

173 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-01

Study Completion Date

2023-10-01

Brief Summary

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When the liquid flow increases, the luminal caliber's stretching amplitude decreases, leading to a higher hydraulic pressure according to Poiseuille's law. In this study, investigators measured the caliber change of the popliteal vein under a rated pressure gradient and evaluated the relationship between popliteal vein compliance and venous clinical severity score (VCSS).

Detailed Description

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Conditions

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Chronic Venous Disease (CVD), Vein Compliance, Venous Clinical Severity Score (VCSS)

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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control group

Popliteal Vein Compliance

Intervention Type OTHER

Compliance of the popliteal vein is calculated as the distensibility, with the ratio of functional caliber/native caliber/cuff pressure value ( mmHg-1 ).

experimental group

Popliteal Vein Compliance

Intervention Type OTHER

Compliance of the popliteal vein is calculated as the distensibility, with the ratio of functional caliber/native caliber/cuff pressure value ( mmHg-1 ).

Interventions

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Popliteal Vein Compliance

Compliance of the popliteal vein is calculated as the distensibility, with the ratio of functional caliber/native caliber/cuff pressure value ( mmHg-1 ).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* C1 to C6 disease using the CEAP (clinical, etiologic, anatomic, pathophysiologic) classification.

Exclusion Criteria

* acute or chronic thrombosis of deep veins, previously received intravenous surgery or injection sclerotherapy, ankle brachial index\<0.90, and concomitant cardiovascular, pulmonary, renal, or metabolic diseases.
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hao Liu

OTHER

Sponsor Role lead

Responsible Party

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Hao Liu

Clinical Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Hao Liu

Guangzhou, Guangdong, China

Site Status

Countries

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China

References

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Liu H, Li L, Wei W, Tang Y, Liu L, Xiao C. Correlation between popliteal vein functional diameter and the severity of chronic venous disease. Phlebology. 2025 Jul;40(6):415-419. doi: 10.1177/02683555241310531. Epub 2024 Dec 21.

Reference Type DERIVED
PMID: 39708049 (View on PubMed)

Other Identifiers

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HaoLiu

Identifier Type: -

Identifier Source: org_study_id