Comparison Of Efficacy Of Hydrocortisone And Methyl Prednisolone In Acute Severe Asthma
NCT ID: NCT06171932
Last Updated: 2023-12-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ENROLLING_BY_INVITATION
60 participants
OBSERVATIONAL
2023-11-26
2024-08-08
Brief Summary
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In this study Investigator will compare the efficacy of hydrocortisone and methyl prednisolone in acute severe asthma that will lead to final result and beneficial effects that will help in early resoloution of symptoms and help in preventing recurrence
Detailed Description
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A local study was conducted in 2009, after that there is a big research gap exists at national level although international literature is available on the same but it can not be generalized to our population due to socio, geographic and economic differences so there is dire need to conduct this study this gives a strong rationale to implement in our settings
Conditions
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Study Design
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ECOLOGIC_OR_COMMUNITY
CROSS_SECTIONAL
Study Groups
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HYDROCORTISONE
Group A will comprise of 30 patients will be treated with 200 mg hydrocortisone followed by 3 doses of hydrocortisone 100 mg 6 hours apart for next 24hrs
No interventions assigned to this group
METHYLPREDNISOLONE
Group B will be treated with methylprednisolone 125 mg stat
Methylprednisolone,
No intervention required
Interventions
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Methylprednisolone,
No intervention required
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patient presenting to emergency department with acute severe asthma
Exclusion Criteria
* Life threatening asthma
* Near fatal asthm
18 Years
50 Years
ALL
No
Sponsors
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University of Karachi
OTHER
Responsible Party
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Inayat Ur Rehman
Principal Investigator
Principal Investigators
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Inayat ur Rehman, MD ER
Role: PRINCIPAL_INVESTIGATOR
zia ud din university karachi
Locations
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Zia ud din hospital university
Karachi, Sindh, Pakistan
Zia ud din university hospital
Karachi, Sindh, Pakistan
Zia ud din university hospitals
Karachi, Sindh, Pakistan
Zia ud din university
Karachi, Sindh, Pakistan
Countries
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References
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Aggarwal P, Bhoi S. Comparing the efficacy and safety of two regimens of sequential systemic corticosteroids in the treatment of acute exacerbation of bronchial asthma. J Emerg Trauma Shock. 2010 Jul;3(3):231-7. doi: 10.4103/0974-2700.66522.
Provided Documents
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Document Type: Study Protocol, Statistical Analysis Plan, and Informed Consent Form
Related Links
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Other Identifiers
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Zia ud din university karachi
Identifier Type: -
Identifier Source: org_study_id