The Use of Stromal Vascular Fraction for Knee Arthrosis

NCT ID: NCT06171204

Last Updated: 2024-11-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-19

Study Completion Date

2026-12-31

Brief Summary

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A trial to investigate the safety and efficacy of SVF for the treatment of knee arthrosis.

Patients will undergo a single liposuction to obtain the SVF. The SVF will then be isolated and frozen in our laboratory. The SVF will then be injected up to 2 times into the fat pad of the patient's knee.

Detailed Description

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Stromal Vascular Fraction (SVF) from adipose tissue is increasingly being used in the clinic for a variety of conditions (skin disorders, joint pain, etc.). SVF is a collective term for cells that can be obtained from liposuction fat. These cells can be separated from the fat by mechanical processing of the liposuction fat combined with an additional centrifugation.

Despite the fact that enough SVF can be isolated after such a liposuction for multiple treatments (\>3), our research group has found a way to safely freeze SVF without significant loss of SVF cells. In this way, a patient would only have to undergo one liposuction and associated anesthesia to be able to obtain multiple SVF treatments.

Conditions

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Knee Arthrosis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Injection of SVF in fat pad of the knee

Knee fat pad injection with SVF at orthopaedics/physical medicine outpatient clinic

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Legal capacity
* Osteochondral lesions
* Inflammatory complaints
* (Peri)tendinitis or tendinopathies and ligamentous injuries
* Impingement complaints
* Arthrofibrosis
* Anterior knee pain
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Ghent

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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UZ GENT

Ghent, Oost-Vlaanderen, Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Bernard Depypere, MD

Role: CONTACT

093325730

Jessie De Kinder

Role: CONTACT

093321373

Other Identifiers

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BC-07772

Identifier Type: -

Identifier Source: org_study_id

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