Ventilator Trigger Sensitivity Adjustment Versus Threshold Inspiratory Muscle Training on Arterial Blood Gases
NCT ID: NCT06167239
Last Updated: 2024-12-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
45 participants
INTERVENTIONAL
2023-05-02
2024-12-31
Brief Summary
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Detailed Description
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Many studies have been done on the effect of IMT by threshold IMT and adjustment of mechanical ventilator trigger separately, thereby, it is rational to compare between two methods of training to know which is more effective to help in weaning process through its effect on ABGs.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Threshold inspiratory muscle trainer
Training of the inspiratory muscles by threshold inspiratory muscle trainer.
Threshold inspiratory muscle trainer or ventilator pressure setting inspiratory muscle training techniques
New techniques to train inspiratory muscles in mechanically ventilated patients
Ventilator pressure setting inspiratory muscle training
Training of the inspiratory muscles by ventilator pressure setting.
Threshold inspiratory muscle trainer or ventilator pressure setting inspiratory muscle training techniques
New techniques to train inspiratory muscles in mechanically ventilated patients
Traditional treatment
Only prescribed medical treatment programme
No interventions assigned to this group
Interventions
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Threshold inspiratory muscle trainer or ventilator pressure setting inspiratory muscle training techniques
New techniques to train inspiratory muscles in mechanically ventilated patients
Eligibility Criteria
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Inclusion Criteria
2. Age: \>18 years.
3. Both sexes will be included.
4. Ventilator mode: Pressure support mode with FiO2≤ 0.5, positive end expiratory pressure (PEEP) will be\<8-10cm/H2Oand respiratory rate \< 25.
5. Conscious oriented patient with Glasgow coma score ≥13.
6. Alertness will be titrated to a Riker Sedation Agitation Score of 4.
7. PH\>7.25, arterial oxygen saturation \>90%.
8. Cardiovascular stability.
9. Maximal inspiratory pressure from 15 to 30 cm H2O and able to trigger spontaneous breaths on ventilator.
Exclusion Criteria
2. Severe breathlessness, when spontaneously breathing.
3. Any progressive neuromuscular disease that would interfere with responding to inspiratory muscle training (non-stationary course).
4. Spinal cord injury.
5. Skeletal pathology (scoliosis, flail chest, spinal instrumentation) that would seriously impair the movement of the chest wall and ribs.
6. Patients on heavy sedation and respiratory muscle paralysis.
7. High peak airway pressure (barotraumas).
8. BMI ≥ 40.
20 Years
55 Years
ALL
No
Sponsors
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Cairo University
OTHER
Responsible Party
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El-Sayed Essam
Lecturer at Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University
Principal Investigators
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Elmasry
Role: STUDY_DIRECTOR
Cairo University
Locations
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Kasr Al Ainy School of Medicine
Cairo, , Egypt
Countries
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Central Contacts
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Facility Contacts
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School of Medicine
Role: primary
Other Identifiers
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P.T.REC/012/004784
Identifier Type: -
Identifier Source: org_study_id