Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
150 participants
OBSERVATIONAL
2021-07-30
2025-09-30
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Obese
Obese participants with BMI \>30
No interventions assigned to this group
Lean
Lean participants with a BMI \<25
No interventions assigned to this group
Bariatric
Participants with scheduled bariatric surgery.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Age 18-55 years
* Written informed consent
* BMI \> 30 kg/m2
N=50 adult lean patients age- and sex-matched to the group of obese patients will be included in this study.
* Age 18-55 years
* Written informed consent
* BMI 18-25 kg/m2
N=50 adult male and female patients with obesity with scheduled bariatric will be included in this study
* Age 18-55 years
* Written informed consent
* BMI \> 35 kg/m2
Exclusion Criteria
* Chronic or acute sinusitis
* Surgical intervention of the nasal cavity or the paranasal sinus
* Use of antibiotics within the last 31 days18
* Current illicit drug abuse including daily marijuana or CBD consumption (≤ 24 g of alcohol per day allowed)
* Any kind of severe chronic disease (e.g. severe heart failure, active cancer disease)
* Use of any kind of decongestant more than twice a week
* Use of cortisone-containing nasal spray within the last 3 months
* Acute allergic rhinitis
* History of neurodegenerative diseases
* History of severe head trauma
* Severe renal impairment (e.g. estimated glomerular filtration rate \<30 ml/min/m2)
18 Years
55 Years
ALL
No
Sponsors
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Katharina Timper
OTHER
Responsible Party
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Katharina Timper
Prof. Dr. med.
Principal Investigators
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Katharina Timper, Prof. Dr. med.
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Basel, Switzerland
Locations
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University Hospital Basel
Basel, , Switzerland
Countries
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Central Contacts
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Facility Contacts
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Katharina Timper, Prof.Dr.med.
Role: primary
Anouk Hoogkamer
Role: backup
Other Identifiers
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2021-01090
Identifier Type: -
Identifier Source: org_study_id