Temporary Peripheral Nerve Stimulation System for Osteoarthritis of the Knee

NCT ID: NCT06152029

Last Updated: 2025-11-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

12 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-15

Study Completion Date

2025-10-20

Brief Summary

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The purpose of this study is to demonstrate the treatment outcomes of patients with chronic knee pain secondary to osteoarthritis that have received a temporary peripheral nerve stimulation system.

Detailed Description

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Conditions

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Osteoarthritis, Knee Osteoarthritis

Keywords

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Peripheral nerve stimulation PNS

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients treated with a temporary PNS system

These patients will receive a temporary PNS system for their knee pain secondary to osteoarthritis

Temporary PNS system

Intervention Type DEVICE

This system remains in place up to 60 days, then removed.

Interventions

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Temporary PNS system

This system remains in place up to 60 days, then removed.

Intervention Type DEVICE

Other Intervention Names

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SPRINT PNS System

Eligibility Criteria

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Inclusion Criteria

* Age of 21 and older
* Will receive a temporary PNS system for the management of chronic knee pain secondary to osteoarthritis
* Be capable of subjective evaluation, able to read and understand English-written questionnaires, and able to read, understand and sign the written informed consent in English
* Be willing and capable of giving informed consent
* Be willing and able to comply with study-related requirements, procedures, and scheduled visits

Exclusion Criteria

* No knee pain at rest
* Same nerve targeted for both Radiofrequency Ablation (RFA) and Peripheral Nerve Stimulation (PNS) in less than 6 months post RFA, if applicable
* Pregnancy
* History of repetitive skin infections
* Vulnerable populations (e.g., prisoners, minors, students, employees)
* Any other condition that may interfere with the ability to participate in a clinical trial (e.g., anatomy that may interfere with lead placement, nerve damage, compromised immune system, uncontrolled diabetes)
* Confounding conditions such as lumbar radiculopathy
* Deep brain stimulation system, implanted active cardiac implant (e.g. pacemaker of defibrillator), or any other implantable neuro-stimulator whose stimulus current pathway may overlap the SPRINT system.
* Be involved in an injury claim under current litigation
* Be a recipient of temporary Social Security Disability Insurance (SSDI) benefits due to chronic pain
* Have a pending or approved worker's compensation claim
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wake Forest University Health Sciences

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Littlefield Lauren, MD

Role: PRINCIPAL_INVESTIGATOR

Aurora Medical Center Oshkosh - 855 N Westhaven Dr

Locations

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Aurora Health Center

Fond du Lac, Wisconsin, United States

Site Status

Aurora Health Oshkosh

Oshkosh, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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23.135E

Identifier Type: OTHER

Identifier Source: secondary_id

IRB00104845

Identifier Type: -

Identifier Source: org_study_id