Virtual Reality for the Management of Pain and Anxiety for Outpatient Interventional Radiology Procedures

NCT ID: NCT06150963

Last Updated: 2023-11-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

107 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-10

Study Completion Date

2022-08-02

Brief Summary

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This study explores the use of virtual reality (VR) to reduce pain and anxiety during thyroid biopsies and PICC line insertions under local anesthesia. One group experienced the procedure with VR, while the other group did not. Participants completed questionnaires before and after the surgery to measure pain and anxiety levels. The main goal is to observe if VR can significantly decrease pain and anxiety during these procedures.

Detailed Description

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This prospective, randomized, controlled study investigates the efficacy of virtual reality (VR) as a means to alleviate pain and anxiety in individuals receiving thyroid biopsies and PICC placements with local anesthesia. This study was conducted at Temple University Hospital between June 2021 and August 2022. A total of 107 patients were randomized into treatment and control groups. The VR experience involved wearing a headset with an immersive 3D visual display and accompanying music, simulating a calming environment. Patients completed Visual Analog Scales for pain and anxiety both before and after the intervention, reflecting their pain and anxiety levels prior to and during the procedure. The primary endpoints were to observe the effect of VR on pain and anxiety in both groups.

Conditions

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Pain Anxiety

Keywords

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Interventional Radiology Thyroid Biopsy Peripherally Inserted Central Catheter Virtual Reality Pain Anxiety Visual Analog Scale

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Thyroid Biopsy (Control)

Patients within this arm received standard procedure thyroid biopsies without virtual reality.

Group Type ACTIVE_COMPARATOR

Standard Procedure Thyroid Biopsy

Intervention Type PROCEDURE

In this procedure the patient lies down on a bed with their neck tilted back to reveal the thyroid gland. The doctor cleans the skin over the nodule and numbs it with a local anesthetic. The doctor will then use an ultrasound device to visualize the nodule and guide a needle to obtain cells through the syringe. This process may be repeated several times to retrieve adequate tissue for analysis.

Thyroid Biopsy (Virtual Reality)

Patients within this arm received standard procedure thyroid biopsies with virtual reality for the length of the procedure.

Group Type EXPERIMENTAL

Virtual Reality

Intervention Type DEVICE

Study participants assigned to the VR intervention group were fitted with an HP Reverb G2 Head Mounted Display (HMD) and a wireless mouse prior to preparation for procedure. One virtual environment was utilized, integrating passive and active participant input via gyroscopic motion detection and computer mouse input.

Standard Procedure Thyroid Biopsy

Intervention Type PROCEDURE

In this procedure the patient lies down on a bed with their neck tilted back to reveal the thyroid gland. The doctor cleans the skin over the nodule and numbs it with a local anesthetic. The doctor will then use an ultrasound device to visualize the nodule and guide a needle to obtain cells through the syringe. This process may be repeated several times to retrieve adequate tissue for analysis.

PICC (Control)

Patients within this arm received standard procedure PICC placements without virtual reality.

Group Type ACTIVE_COMPARATOR

Standard Procedure PICC Placement

Intervention Type PROCEDURE

In this procedure the patient lies down on a bed and has their arm cleaned and then numbed with a local anesthetic. The doctor then uses an ultrasound to locate a suitable vein in the arm, typically above the elbow. The physician then makes a small incision in the skin and inserts a needle into the vein, followed by guidance of the Peripherally Inserted Central Catheter (PICC) through the needle until it reaches a large vein near the heart. The final position is confirmed by X-ray and the PICC line is secured at the site of insertion.

PICC (Virtual Reality)

Patients within this arm received standard procedure PICC placements with virtual reality for the length of the procedure.

Group Type EXPERIMENTAL

Virtual Reality

Intervention Type DEVICE

Study participants assigned to the VR intervention group were fitted with an HP Reverb G2 Head Mounted Display (HMD) and a wireless mouse prior to preparation for procedure. One virtual environment was utilized, integrating passive and active participant input via gyroscopic motion detection and computer mouse input.

Standard Procedure PICC Placement

Intervention Type PROCEDURE

In this procedure the patient lies down on a bed and has their arm cleaned and then numbed with a local anesthetic. The doctor then uses an ultrasound to locate a suitable vein in the arm, typically above the elbow. The physician then makes a small incision in the skin and inserts a needle into the vein, followed by guidance of the Peripherally Inserted Central Catheter (PICC) through the needle until it reaches a large vein near the heart. The final position is confirmed by X-ray and the PICC line is secured at the site of insertion.

Interventions

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Virtual Reality

Study participants assigned to the VR intervention group were fitted with an HP Reverb G2 Head Mounted Display (HMD) and a wireless mouse prior to preparation for procedure. One virtual environment was utilized, integrating passive and active participant input via gyroscopic motion detection and computer mouse input.

Intervention Type DEVICE

Standard Procedure Thyroid Biopsy

In this procedure the patient lies down on a bed with their neck tilted back to reveal the thyroid gland. The doctor cleans the skin over the nodule and numbs it with a local anesthetic. The doctor will then use an ultrasound device to visualize the nodule and guide a needle to obtain cells through the syringe. This process may be repeated several times to retrieve adequate tissue for analysis.

Intervention Type PROCEDURE

Standard Procedure PICC Placement

In this procedure the patient lies down on a bed and has their arm cleaned and then numbed with a local anesthetic. The doctor then uses an ultrasound to locate a suitable vein in the arm, typically above the elbow. The physician then makes a small incision in the skin and inserts a needle into the vein, followed by guidance of the Peripherally Inserted Central Catheter (PICC) through the needle until it reaches a large vein near the heart. The final position is confirmed by X-ray and the PICC line is secured at the site of insertion.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age over 18
* Scheduled to receive Fine-Needle Aspiration (FNA) Thyroid Biopsy
* Scheduled to receive Peripherally Inserted Central Catheters (PICC)

Exclusion Criteria

* Declining to participate
* Inability to provide consent
* Emergency procedures
* Administration of general anesthesia/moderate sedation
* Visual or hearing deficits
* Pregnancy
* Current prisoner status
* Nerve or sensory deficits over area of procedure
* COVID-19 positive status
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Temple University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hillel Maresky, M.D.

Role: PRINCIPAL_INVESTIGATOR

Temple University

Locations

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Temple University Hospital

Philadelphia, Pennsylvania, United States

Site Status

Countries

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United States

References

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Mallari B, Spaeth EK, Goh H, Boyd BS. Virtual reality as an analgesic for acute and chronic pain in adults: a systematic review and meta-analysis. J Pain Res. 2019 Jul 3;12:2053-2085. doi: 10.2147/JPR.S200498. eCollection 2019.

Reference Type RESULT
PMID: 31308733 (View on PubMed)

Gold JI, Kim SH, Kant AJ, Joseph MH, Rizzo AS. Effectiveness of virtual reality for pediatric pain distraction during i.v. placement. Cyberpsychol Behav. 2006 Apr;9(2):207-12. doi: 10.1089/cpb.2006.9.207.

Reference Type RESULT
PMID: 16640481 (View on PubMed)

Other Identifiers

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27238

Identifier Type: -

Identifier Source: org_study_id