MedDataX Logo

Barley Beta-glucan, Glycemic Control, and Appetite

NCT ID: NCT06146322

Last Updated: 2023-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-01

Study Completion Date

2020-10-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Novel barley varieties high in the soluble fiber β-glucan have the capacity to improve population health through improving glycemic control. Sweetened and unsweetened wholegrain barley foods were tested in a randomized, controlled, crossover human clinical trial to assess impact on postprandial appetite and food intake.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Diet, Healthy Blood Sugar; High Diabetes Appetite and General Nutritional Disorders Appetitive Behavior

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

WR

Unsweetened preload condition: 240 mL white glutinous rice, 250 kcal, 0 g β-glucan

Intervention Type OTHER

LB

Unsweetened preload condition: 240 mL low β-glucan barley, 250 kcal, \~4 g β-glucan

Intervention Type OTHER

MB

Unsweetened preload condition: 240 mL medium β-glucan barley, 250 kcal, \~5 g β-glucan

Intervention Type OTHER

HB

Unsweetened preload condition: 240 mL high β-glucan barley, 250 kcal, \~6 g β-glucan

Intervention Type OTHER

WR+50g HFCS

Sweetened condition with high fructose corn syrup (HFCS): 240 mL white glutinous rice + 50g HFCS, 391 kcal, 0 g β-glucan

Intervention Type OTHER

LB + 50 g HFCS

Sweetened condition with high fructose corn syrup (HFCS): 240 mL low β-glucan barley + 50 g HFCS, 391 kcal, \~4 g β-glucan

Intervention Type OTHER

MB + 50 g HFCS

Sweetened condition with high fructose corn syrup (HFCS): 240 mL medium β-glucan barley + 50 g HFCS, 391 kcal, \~5 g β-glucan

Intervention Type OTHER

HB + 50 g HFCS

Sweetened condition with high fructose corn syrup (HFCS): 240 mL high β-glucan barley + 50 g HFCS, 391 kcal, \~6 g β-glucan

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18-50 years of age
* Body Mass Index (BMI) values of 18.5-40.0 kg/m2
* Normal fasting blood glucose (\<100 mg/dL)

Exclusion Criteria

* Use of medications known to be associated with weight change (e.g., beta-blockers)
* Use of steroid pills or shots such as prednisone or cortisone
* Use of nicotine
* Weight change of ten or more pounds in the last three months
* Major daily variation in physical activity (e.g., athletes in training)
* History of extensive small bowel surgery or surgery to treat obesity
* History of heart attack, stroke, or bypass
* History of cancer within the last five years (exception: non-melanoma skin cancer)
* Recent or current medical diagnosis or medical treatment that would alter appetite, energy needs, satiety, and/or could impact the results of the trial
* Medical diagnoses of diabetes, cardiovascular disease, high levels of blood lipids, asthma, cold, and flu (exception: hypertension, if treated with medication prescribed more than three months prior to the screening activity)
* Fear of blood or needles
* Dietary restrictions that would interfere with consuming test foods (e.g., gluten intolerance, vegan, corn syrup allergy)
* Following a weight modification diet
* Sensitive to food textures present in the test foods
* Following personal schedules that would not permit attendance at all scheduled testing sessions
* Unable to comprehend the nature of the trial or instructions
* Unable to understand English sufficiently to complete the trial
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Washington State University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Martine Perrigue

Assistant Professor, Nutrition and Exercise Physiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Martine Perrigue, PhD, RDN

Role: PRINCIPAL_INVESTIGATOR

Washington State University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Washington State University

Spokane, Washington, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

17735

Identifier Type: -

Identifier Source: org_study_id