Study of Human Brain-Gut Axis and Gut Microbiome in Patients With Brain Lesions - Repository for Neuroscience Research
NCT ID: NCT06117930
Last Updated: 2026-02-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
100 participants
OBSERVATIONAL
2024-02-28
2029-12-13
Brief Summary
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Detailed Description
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I. To establish a Mayo Clinic Florida Brain Tumor-Gut Axis Human Biorepository by sequential collection of fecal, urine, blood, saliva, and/or tissue samples and clinical patient information.
II. To use spatial transcriptome/proteomics/multi-omics coupled with microbiome data from various sources including brain tissue and stool samples to understand how microbiota could impact disease development, progression, and treatment response in patients with brain cancer.
III. To study the effect of microbiome and potential relationships and/or microbiome reconstruction to impact patient's clinical outcomes including chemo, radiation, immunotherapy and/or cellular therapy.
OUTLINE: This is an observational study.
Participants undergo blood, tissue, saliva, urine and stool sample collection and complete questionnaires on study.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Observational
Participants undergo blood, tissue, saliva, urine and stool sample collection and complete questionnaires on study.
Non-Interventional Study
Non-interventional study
Interventions
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Non-Interventional Study
Non-interventional study
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
Yes
Sponsors
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Mayo Clinic
OTHER
Responsible Party
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Principal Investigators
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Alfredo Quinones-Hinojosa, M.D.
Role: PRINCIPAL_INVESTIGATOR
Mayo Clinic
Locations
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Mayo Clinic in Florida
Jacksonville, Florida, United States
Countries
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Central Contacts
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Facility Contacts
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Related Links
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Mayo Clinic Clinical Trials
Other Identifiers
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NCI-2023-04797
Identifier Type: REGISTRY
Identifier Source: secondary_id
23-001388
Identifier Type: OTHER
Identifier Source: secondary_id
MC230707
Identifier Type: -
Identifier Source: org_study_id
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