ARTIFICIAL INTELLIGENCE FOR MASS SCREENING OF THE DIABETIC RETINOPATHY IN THE CHERNIVTSI REGION (Pilot Study)

NCT ID: NCT06112691

Last Updated: 2023-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

660 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-02-01

Study Completion Date

2024-11-30

Brief Summary

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The purpose of this study is to create a patient-centric environment for early detection of DR with AI-driven solutions.

Detailed Description

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The purpose of this study is to create a patient-centric environment for early detection of DR with AI-driven solutions.

This study is planned as a follow-up. Participants who meet the eligibility criteria will be recruited from sites staffed by the trained photographers. After assessing eligibility and securing written informed consent, fundus photographs will be captured using a nonmydriatic ocular fundus camera. Images will be taken according to a specific RAssbyAI Check Eye's imaging protocol provided to camera operator, and then analyzed by the RAssbyAI Check Eye's. The photography protocol consists of two images of the ocular fundus (one optic disc centered, one fovea centered).

Conditions

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Diabetic Retinopathy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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main group

diabetes mellitus

taking fundus photos using non-mydriatic fundus camera - FundusScope Rodenstock

Intervention Type DEVICE

using artificial intelligence to identify diabetic retinopathy in the early stages using fundus photography.

control group

without diagnosis of diabetes mellitus without retinal diseases

taking fundus photos using non-mydriatic fundus camera - FundusScope Rodenstock

Intervention Type DEVICE

using artificial intelligence to identify diabetic retinopathy in the early stages using fundus photography.

Interventions

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taking fundus photos using non-mydriatic fundus camera - FundusScope Rodenstock

using artificial intelligence to identify diabetic retinopathy in the early stages using fundus photography.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Documented diagnosis of Diabetes mellitus as defined by:

A. Having met the criteria established by either the World Health Organization (WHO) or the American Diabetes Association (ADA) B. Hemoglobin A1c (HbA1c)\>= 6.5% based on repeated assessments C. Fasting Plasma Glucose (FPG) \>= 126 mg/dL (7.0 mmol/L) based on repeated assessments D. Oral Glucose Tolerance test with 2 hr plasma glucose \>= 200 mg/dL (11.1mmol/L) using equivalent of 75g anhydrous glucose dose in water.

E. Symptoms of hyperglycemia or hyperglycemic crisis with random plasma glucose \>=200mg/dL (11.1 mmol/L).
2. Understanding of the Study and willingness and ability to sign informed consent
3. Patient age 18 or above
4. Diagnostic for diabetes: 4a) Type 1 diabetes of a lest 5 years of evolution; or 4b) Type 2 diabetes

\-

Exclusion Criteria

1. Patients under 18 years of age;
2. Failure to give informed consent;
3. Presence of retinal diseases - acquired disease: age-related macular degeneration (AMD), occlusion of retinal vessels (ORV), etc.; birth defects: coloboma of choroid or optic nerve disc, etc.; hereditary diseases: retinitis pigmentosa, angioid streaks of the retina, etc.
4. A patient who has already undergone treatment (surgery, laser, etc.) for any disease of the retina: age-related macular degeneration (AMD), retinal vascular occlusion (ARV), etc. These patients should be excluded or allocated to a separate group.
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Komisarenko Institute of Endocrinology and Metobolism

OTHER_GOV

Sponsor Role collaborator

CheckEye LLC

INDUSTRY

Sponsor Role collaborator

The Filatov Institute of Eye Diseases and Tissue Therapy

OTHER

Sponsor Role lead

Responsible Party

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Andrii Korol, MD, PhD

MD, PhD, DMedSc

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Andrii MD Korol, PhD

Role: PRINCIPAL_INVESTIGATOR

The Filatov Institute of Eye Diseases and Tissue Therapy

Locations

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The Filatov Institute of Eye Diseases and Tissue Therapy

Odesa, , Ukraine

Site Status RECRUITING

Countries

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Ukraine

Central Contacts

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Andrii MD Korol, PhD

Role: CONTACT

380936327266

Olha MD Pohosian

Role: CONTACT

380932084927

Other Identifiers

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24.01.2022

Identifier Type: -

Identifier Source: org_study_id

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