Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
40 participants
INTERVENTIONAL
2024-04-16
2026-04-30
Brief Summary
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Detailed Description
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Through blood specimens, the researchers will observe biomarkers such as cortisol levels and inflammatory markers. Data will be collected from wearable sensors to observe the effects of beneficial exposomes on areas such as cardiovascular health and sleep quality. There will be surveys to understand well-being, stress, and mood. Through such observations, this study aims to understand the positive impacts of intentional exposure to selected compounds found in nature.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
NONE
Study Groups
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Group A- Natural Compound A to Natural Compound B to Natural Compound C
* Cycle 1 (4 weeks): use diffused "Natural Compound A" (essential oil) in a diffuser every night when sleeping
* Cycle 2 (4 weeks): will not use compounds/diffuser (wash-out period)
* Cycle 3 (4 weeks): use diffused "Natural Compound B" (essential oil) in a diffuser every night when sleeping
* Cycle 4 (4 weeks): will not use compounds/diffuser (post-intervention observation period)
* Cycle 3 (4 weeks): use diffused "Natural Compound C" (control) in a diffuser every night when sleeping
* Cycle 4 (4 weeks): will not use compounds/diffuser (post-intervention observation period)
There will be 3 natural compounds; the intervention compounds essential oils and are commercially available and there is a control compound (water). They will be used as intended with diffusers.
Natural Compound A (Hinoki essential oil)
Participants will use "Natural Compound A" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Natural Compound B (Lemon essential oil)
Participants will use "Natural Compound B" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Natural Compound C (Control/Water)
Participants will use "Natural Compound C" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Group B- Natural Compound B to Natural Compound C to Natural Compound A
* Cycle 1 (4 weeks): use diffused "Natural Compound B" (essential oil) in a diffuser every night when sleeping
* Cycle 2 (4 weeks): will not use compounds/diffuser (wash-out period)
* Cycle 3 (4 weeks): use diffused "Natural Compound C" (control) in a diffuser every night when sleeping
* Cycle 4 (4 weeks): will not use compounds/diffuser (post-intervention observation period)
* Cycle 3 (4 weeks): use diffused "Natural Compound A" (essential oil) in a diffuser every night when sleeping
* Cycle 4 (4 weeks): will not use compounds/diffuser (post-intervention observation period)
There will be 3 natural compounds; the intervention compounds essential oils and are commercially available and there is a control compound (water). They will be used as intended with diffusers.
Natural Compound A (Hinoki essential oil)
Participants will use "Natural Compound A" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Natural Compound B (Lemon essential oil)
Participants will use "Natural Compound B" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Natural Compound C (Control/Water)
Participants will use "Natural Compound C" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Group C- Natural Compound C to Natural Compound A to Natural Compound B
* Cycle 1 (4 weeks): use diffused "Natural Compound C" (control) in a diffuser every night when sleeping
* Cycle 2 (4 weeks): will not use compounds/diffuser (wash-out period)
* Cycle 3 (4 weeks): use diffused "Natural Compound A" (essential oil) in a diffuser every night when sleeping
* Cycle 4 (4 weeks): will not use compounds/diffuser (post-intervention observation period)
* Cycle 3 (4 weeks): use diffused "Natural Compound B" (essential oil) in a diffuser every night when sleeping
* Cycle 4 (4 weeks): will not use compounds/diffuser (post-intervention observation period)
There will be 3 natural compounds; the intervention compounds essential oils and are commercially available and there is a control compound (water). They will be used as intended with diffusers.
Natural Compound A (Hinoki essential oil)
Participants will use "Natural Compound A" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Natural Compound B (Lemon essential oil)
Participants will use "Natural Compound B" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Natural Compound C (Control/Water)
Participants will use "Natural Compound C" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Interventions
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Natural Compound A (Hinoki essential oil)
Participants will use "Natural Compound A" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Natural Compound B (Lemon essential oil)
Participants will use "Natural Compound B" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Natural Compound C (Control/Water)
Participants will use "Natural Compound C" in a diffuser every night for 4 weeks. Diffuser will be placed near participant's bed and will be used during the entire time they are asleep (about 8 hours, every night).
Eligibility Criteria
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Inclusion Criteria
* Read, speak, and understand English
* Live in the US territory
Exclusion Criteria
* Is pregnant
* Is breastfeeding
* Has epilepsy
* Has allergies to Cupressaceae family of plants, common plants include redwoods, junipers, cypress, cedar, fir, and sequoia
18 Years
ALL
Yes
Sponsors
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Stanford University
OTHER
Responsible Party
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Michael Snyder
Professor of Genetics & Genetics Department Chair
Principal Investigators
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Michael Snyder, PhD
Role: PRINCIPAL_INVESTIGATOR
Stanford University
Locations
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Stanford University
Palo Alto, California, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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71135
Identifier Type: -
Identifier Source: org_study_id