Combined Rehabilitation With ALA, ALC, Resveratrol and Vitamin D in Discogenic Sciatica in Young People
NCT ID: NCT06078163
Last Updated: 2023-10-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
130 participants
INTERVENTIONAL
2022-07-01
2023-08-22
Brief Summary
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The main questions we intend to answer are:
* Is this combined treatment more effective in reducing pain?
* Is the combined treatment useful for improving postural alterations, reducing the intake of painkillers and the number of days of absence from work and improving the quality of life?
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
SINGLE
Study Groups
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Treatment Group
Treatment Group was composed of patients who will undergo daily pharmacological therapy with Alpha Lipoic Acid 600 mg, L-acetylcarnitine 1000 mg, Resvelatrol 50 mg, Vit D3 800UI for 30 consecutive days in combination with a rehabilitation protocol lasting 20 sessions
supplementation
daily pharmacological therapy with Alpha Lipoic Acid 600 mg, L-acetylcarnitine 1000 mg, Resvelatrol 50 mg, vit D3 800UI for 30 consecutive days in combination with a rehabilitation protocol lasting 20 sessions
rehabilitation
rehabilitation protocol lasting 20 sessions.
Control Group
Control Group was composed of patients who will only undergo a rehabilitation protocol lasting 20 sessions.
rehabilitation
rehabilitation protocol lasting 20 sessions.
Interventions
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supplementation
daily pharmacological therapy with Alpha Lipoic Acid 600 mg, L-acetylcarnitine 1000 mg, Resvelatrol 50 mg, vit D3 800UI for 30 consecutive days in combination with a rehabilitation protocol lasting 20 sessions
rehabilitation
rehabilitation protocol lasting 20 sessions.
Eligibility Criteria
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Inclusion Criteria
* pain with NRS scale score between 5 and 7 points
* symptoms attributable to lumbosciatica which occurred no more than 4 weeks ago
* pharmacological wash out of NSAIDs and corticosteroids for at least a week
* presence of L4-L5, L5-S1 disc herniation diagnosed with lumbar MRI performed within 3 months
* absence of ongoing infectious episodes;
* written consent for participation in the study.
Exclusion Criteria
* Sciatica not of disc origin
* Neurological disorders
* Presence of scoliosis \>20° of Cobb
* Previous spinal surgery
* Pregnancy and/or breastfeeding
18 Years
45 Years
ALL
Yes
Sponsors
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University of Palermo
OTHER
Responsible Party
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Prof.ssa Giulia Letizia Mauro
Professor
Locations
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Functional Recovery and Rehabilitation Unit of the A.O.U.P. Paolo Giaccone
Palermo, , Italy
Countries
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Other Identifiers
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MFR0042023
Identifier Type: -
Identifier Source: org_study_id
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