A Study of Remote Asthma Management Using an Integrated Artificial Intelligence-assisted EHR Dashboard and Mobile Device Compared With Usual Asthma Care to Treat 6-17 Year Old Patients

NCT ID: NCT06062433

Last Updated: 2025-08-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

47 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-05

Study Completion Date

2025-06-05

Brief Summary

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The main purpose of this study is to look at whether clinicians and their patients with asthma can satisfactorily perform remote asthma management at home (not visiting clinic) by using an artificial intelligence tool called Asthma-Guidance and Prediction System combined with a home monitoring device called AsthmaTuner.

Detailed Description

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Conditions

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Asthma in Children

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Pediatric Asthma Intervention Group

Along with clinical standard of care for asthma, subjects will have Asthma-Guidance and Prediction System (A-GPS) with AsthmaTuner (AT) integrated into care.

Group Type EXPERIMENTAL

AsthmaTuner

Intervention Type DEVICE

Phone application and spirometer for self-management of asthma

Asthma-Guidance and Prediction System

Intervention Type OTHER

Artificial Intelligence (AI)-assisted clinical decision support system which extracts pertinent patient data related to asthma management from electronic health record

Pediatric Asthma Control Group

Subjects will receive clinical standard of care for asthma.

Group Type NO_INTERVENTION

No interventions assigned to this group

Clinician Control Group

Clinicians will provide clinical standard of care for pediatric asthma patients.

Group Type NO_INTERVENTION

No interventions assigned to this group

Clinician Intervention Group

Clinicians will integrate Asthma-Guidance and Prediction System (A-GPS) with AsthmaTuner (AT) into clinical standard of care for asthma.

Group Type EXPERIMENTAL

AsthmaTuner

Intervention Type DEVICE

Phone application and spirometer for self-management of asthma

Asthma-Guidance and Prediction System

Intervention Type OTHER

Artificial Intelligence (AI)-assisted clinical decision support system which extracts pertinent patient data related to asthma management from electronic health record

Asthma Care Coordinator Control Group

Asthma Care Coordinators will provide clinical standard of care for pediatric asthma patients.

Group Type NO_INTERVENTION

No interventions assigned to this group

Asthma Care Coordinator Intervention Group

Asthma Care Coordinators will integrate Asthma-Guidance and Prediction System (A-GPS) with AsthmaTuner (AT) into clinical standard of care for asthma.

Group Type EXPERIMENTAL

AsthmaTuner

Intervention Type DEVICE

Phone application and spirometer for self-management of asthma

Asthma-Guidance and Prediction System

Intervention Type OTHER

Artificial Intelligence (AI)-assisted clinical decision support system which extracts pertinent patient data related to asthma management from electronic health record

Interventions

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AsthmaTuner

Phone application and spirometer for self-management of asthma

Intervention Type DEVICE

Asthma-Guidance and Prediction System

Artificial Intelligence (AI)-assisted clinical decision support system which extracts pertinent patient data related to asthma management from electronic health record

Intervention Type OTHER

Other Intervention Names

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AT A-GPS

Eligibility Criteria

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Inclusion Criteria

Clinician participants are eligible to be included in the study only if all of the following criteria apply:

* Employed as consultant or nurse practitioner at study sites.
* Able to provide written consent.
* Are willing to follow recommendations to schedule/see participant and their caregiver for regular asthma follow-up care every 3-6 months.

All asthma care coordinators who are involved in the usual care of pediatric participants will also be recruited for inclusion in the study.

Pediatric participants are eligible to be included in the study only if all of the following criteria apply:

* Ages 6-17 years old with diagnosis of asthma.
* Have a caregiver who is willing to participate alongside pediatric participant and to have regular asthma follow-up care every 3-6 months.
* Adolescent participants ages 13-17 years and their caregivers are able to give written informed consent; or child participants ages 7-12 years are able to provide assent and their caregivers are able to give written informed consent (subjects who are 6 years old will be waived).
* Both participant and caregiver are able to read and write in English.
* Receive pediatric primary care at study sites from participating study clinician.
* Access for caregiver and/or adolescent participants to an Android or iPhone with Wi-Fi access and availability for at least monthly use.
* Active asthma defined by at least one clinic visit with a diagnosis of asthma per EHR or on active asthma control or rescue medication in the past 12 months. Priority will be given to those with persistent asthma on inhaled corticosteroids therapy or those with poorly controlled asthma defined by any of the following criteria in the past 12 months, except item v (past 2-week period); i. Asthma Control Test for adolescents ≥ 12 years or Childhood Asthma Control Test for children \< 12 years (score\< 20); ii. ED visit for asthma; or iii. Hospitalization for asthma; or iv. Unscheduled outpatient visit for asthma requiring oral corticosteroid use; or v. Asthma symptoms at the screening interview, including 1) more than 2 days per week shortness of breath, wheezing, chest tightness, or 2) more than 1 night awakening due to asthma in the past 2-week period.
* Participant had their latest asthma follow-up visit more than 3 months prior to the screening date of the study.

Exclusion Criteria

Pediatric participants who do not meet the eligibility criteria described above will be excluded and those will be excluded from the study if any of the following criteria apply:

* Major medical problems prohibiting study participation and inability to perform study procedures (including spirometry); suspected symptoms of exercise-induced laryngeal obstruction (EILO), tracheobronchial foreign body at or about the incidence date of asthma, wheezing occurring only in response to anesthesia or medications, bullous emphysema or pulmonary fibrosis on chest radiograph, PiZZ alpha1-antitrypsin, cystic fibrosis, or other major chest disease such as severe kyphoscoliosis or bronchiectasis.
* Pediatric participant pregnancy.
* Hyposensitization therapy for \> 3 months prior to study enrollment.
* Participation in any other interventional studies for asthma within 1 month prior to study.
Minimum Eligible Age

6 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Young Juhn

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Young Juhn, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic

Rochester, Minnesota, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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22-001438

Identifier Type: -

Identifier Source: org_study_id

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