Trial Outcomes & Findings for Patient Portal Flu Vaccine Reminders (RCT 6) (NCT NCT06062264)
NCT ID: NCT06062264
Last Updated: 2025-04-20
Results Overview
Percent of patients with annual influenza vaccination (between 10/4/23 - 4/1/24) among adult patients. Outcomes will be assessed via vaccine data extraction from the electronic health record and external claims and pharmacy data. The index patients must also be an active UCLA Health MyChart user (\>= 1 login over the last 12 months from 8/1/23, excluding activity on the user's initial profile activation date). Individuals not affiliated with any primary care practice will be excluded from the primary analysis.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
22233 participants
Primary outcome timeframe
6 months
Results posted on
2025-04-20
Participant Flow
Participant milestones
| Measure |
Portal-Based PCP Video Reminder Message
Participants in their arm will receive up to 3 portal-based messages with a video recorded message from their own primary care physician encouraging them to receive the influenza vaccine.
Portal-based Video Message: Video recorded by physician encouraging patients to receive influenza vaccine. Sent via the patient portal.
|
Portal-Based PCP Infographic Reminder Message
Participants in their arm will receive up to 3 portal-based messages with an infographic message with an image of their own primary care physician encouraging them to receive the influenza vaccine.
Portal-based Infographic Message: Infographic with information about the influenza vaccine and an image of the physician. Sent via the patient portal.
|
Standard Health System Portal Messages
Participants in this arm will only receive standard-of-care health system portal messages, and will not receive study-based messages.
|
|---|---|---|---|
|
Overall Study
STARTED
|
7410
|
7406
|
7417
|
|
Overall Study
COMPLETED
|
7410
|
7406
|
7417
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Patient Portal Flu Vaccine Reminders (RCT 6)
Baseline characteristics by cohort
| Measure |
Portal-Based PCP Video Reminder Message
n=7410 Participants
Participants in their arm will receive up to 3 portal-based messages with a video recorded message from their own primary care physician encouraging them to receive the influenza vaccine.
Portal-based Video Message: Video recorded by physician encouraging patients to receive influenza vaccine. Sent via the patient portal.
|
Portal-Based PCP Infographic Reminder Message
n=7406 Participants
Participants in their arm will receive up to 3 portal-based messages with an infographic message with an image of their own primary care physician encouraging them to receive the influenza vaccine.
Portal-based Infographic Message: Infographic with information about the influenza vaccine and an image of the physician. Sent via the patient portal.
|
Standard Health System Portal Messages
n=7417 Participants
Participants in this arm will only receive standard-of-care health system portal messages, and will not receive study-based messages.
|
Total
n=22233 Participants
Total of all reporting groups
|
|---|---|---|---|---|
|
Age, Categorical
<=18 years
|
1058 Participants
n=93 Participants
|
1085 Participants
n=4 Participants
|
1057 Participants
n=27 Participants
|
3200 Participants
n=483 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
4908 Participants
n=93 Participants
|
4915 Participants
n=4 Participants
|
4881 Participants
n=27 Participants
|
14704 Participants
n=483 Participants
|
|
Age, Categorical
>=65 years
|
1444 Participants
n=93 Participants
|
1406 Participants
n=4 Participants
|
1479 Participants
n=27 Participants
|
4329 Participants
n=483 Participants
|
|
Sex: Female, Male
Female
|
4647 Participants
n=93 Participants
|
4658 Participants
n=4 Participants
|
4668 Participants
n=27 Participants
|
13973 Participants
n=483 Participants
|
|
Sex: Female, Male
Male
|
2763 Participants
n=93 Participants
|
2748 Participants
n=4 Participants
|
2749 Participants
n=27 Participants
|
8260 Participants
n=483 Participants
|
|
Race/Ethnicity, Customized
Asian
|
776 Participants
n=93 Participants
|
795 Participants
n=4 Participants
|
843 Participants
n=27 Participants
|
2414 Participants
n=483 Participants
|
|
Race/Ethnicity, Customized
Black
|
326 Participants
n=93 Participants
|
352 Participants
n=4 Participants
|
338 Participants
n=27 Participants
|
1016 Participants
n=483 Participants
|
|
Race/Ethnicity, Customized
White
|
3797 Participants
n=93 Participants
|
3618 Participants
n=4 Participants
|
3635 Participants
n=27 Participants
|
11050 Participants
n=483 Participants
|
|
Race/Ethnicity, Customized
Other (Unknown or Multiple)
|
2511 Participants
n=93 Participants
|
2641 Participants
n=4 Participants
|
2601 Participants
n=27 Participants
|
7753 Participants
n=483 Participants
|
|
Race/Ethnicity, Customized
Hispanic
|
1020 Participants
n=93 Participants
|
1008 Participants
n=4 Participants
|
1044 Participants
n=27 Participants
|
3072 Participants
n=483 Participants
|
|
Race/Ethnicity, Customized
Non-Hispanic or Unknown
|
6390 Participants
n=93 Participants
|
6398 Participants
n=4 Participants
|
6373 Participants
n=27 Participants
|
19161 Participants
n=483 Participants
|
|
Primary Insurer
Private
|
6307 Participants
n=93 Participants
|
6302 Participants
n=4 Participants
|
6269 Participants
n=27 Participants
|
18878 Participants
n=483 Participants
|
|
Primary Insurer
Public
|
996 Participants
n=93 Participants
|
996 Participants
n=4 Participants
|
1035 Participants
n=27 Participants
|
3027 Participants
n=483 Participants
|
|
Primary Insurer
Other/Unknown/Multiple
|
107 Participants
n=93 Participants
|
108 Participants
n=4 Participants
|
113 Participants
n=27 Participants
|
328 Participants
n=483 Participants
|
|
Influenza Vaccine History
None
|
1949 Participants
n=93 Participants
|
1974 Participants
n=4 Participants
|
1964 Participants
n=27 Participants
|
5887 Participants
n=483 Participants
|
|
Influenza Vaccine History
Prior Vaccination
|
5461 Participants
n=93 Participants
|
5432 Participants
n=4 Participants
|
5453 Participants
n=27 Participants
|
16346 Participants
n=483 Participants
|
PRIMARY outcome
Timeframe: 6 monthsPercent of patients with annual influenza vaccination (between 10/4/23 - 4/1/24) among adult patients. Outcomes will be assessed via vaccine data extraction from the electronic health record and external claims and pharmacy data. The index patients must also be an active UCLA Health MyChart user (\>= 1 login over the last 12 months from 8/1/23, excluding activity on the user's initial profile activation date). Individuals not affiliated with any primary care practice will be excluded from the primary analysis.
Outcome measures
| Measure |
Portal-Based PCP Video Reminder Message
n=7410 Participants
Participants in their arm will receive up to 3 portal-based messages with a video recorded message from their own primary care physician encouraging them to receive the influenza vaccine.
Portal-based Video Message: Video recorded by physician encouraging patients to receive influenza vaccine. Sent via the patient portal.
|
Portal-Based PCP Infographic Reminder Message
n=7406 Participants
Participants in their arm will receive up to 3 portal-based messages with an infographic message with an image of their own primary care physician encouraging them to receive the influenza vaccine.
Portal-based Infographic Message: Infographic with information about the influenza vaccine and an image of the physician. Sent via the patient portal.
|
Standard Health System Portal Messages
n=7417 Participants
Participants in this arm will only receive standard-of-care health system portal messages, and will not receive study-based messages.
|
|---|---|---|---|
|
Receipt of the Annual Influenza Vaccine Among Index Patients
|
3557 Participants
|
3518 Participants
|
3479 Participants
|
SECONDARY outcome
Timeframe: 6 monthsPercent of patients with annual influenza vaccination (between 10/4/23 - 4/1/24) among pediatric index patients. Outcomes will be assessed via vaccine data extraction from the electronic health record and external claims and pharmacy data. The index patients must also be an active UCLA Health MyChart user (\>= 1 login over the last 12 months from 8/1/23, excluding activity on the user's initial profile activation date). Individuals not affiliated with any primary care practice will be excluded from the primary analysis.
Outcome measures
| Measure |
Portal-Based PCP Video Reminder Message
n=1058 Participants
Participants in their arm will receive up to 3 portal-based messages with a video recorded message from their own primary care physician encouraging them to receive the influenza vaccine.
Portal-based Video Message: Video recorded by physician encouraging patients to receive influenza vaccine. Sent via the patient portal.
|
Portal-Based PCP Infographic Reminder Message
n=1085 Participants
Participants in their arm will receive up to 3 portal-based messages with an infographic message with an image of their own primary care physician encouraging them to receive the influenza vaccine.
Portal-based Infographic Message: Infographic with information about the influenza vaccine and an image of the physician. Sent via the patient portal.
|
Standard Health System Portal Messages
n=1057 Participants
Participants in this arm will only receive standard-of-care health system portal messages, and will not receive study-based messages.
|
|---|---|---|---|
|
Receipt of the Annual Influenza Vaccine Among Pediatric Index Patients
|
618 Participants
|
598 Participants
|
576 Participants
|
Adverse Events
Portal-Based PCP Video Reminder Message
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Portal-Based PCP Infographic Reminder Message
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Standard Health System Portal Messages
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place