"Effect of Screening Using Imaging (CT/ EUS) on Early Detection of Pancreatic Ductal Adenocarcinoma (PDAC) in Patients With New Onset Diabetes (NOD)" - A Prospective Pilot Observational Study

NCT ID: NCT06044064

Last Updated: 2023-10-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-12-01

Study Completion Date

2027-09-01

Brief Summary

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To assess whether EUS (Endoscopic Ultrasound) can serve as a valuable diagnostic tool for identifying PDAC at an early stage in individuals who have recently been diagnosed with diabetes.

Purpose: To improve the rates of early detection of pancreatic cancer.

Pancreatic ductal adenocarcinoma (PDAC) is a type of cancer that starts in the pancreas, a gland located in your abdomen. It happens when some cells in the pancreas start growing abnormally and form a cancer.

Detailed Description

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Conditions

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Pancreatic Ductal Adenocarcinoma (PDAC)

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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A blood sample for CA 19-9 (cancer detection test)

* A blood sample for CA 19-9 (cancer detection test) levels will be taken at baseline.
* Contrast CT abdomen - Pancreas protocol will be done at baseline.
* EUS (Endoscopic Ultrasound) under moderate sedation will be done at baseline to you.
* If suspicious lesion is found on examination, Fine Needle Aspiration - FNA will be done.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age \> 50 years
* Patients diagnosed with diabetes based on FBS/ PPBS/ HbA1C
* Presence of atleast 1 FBS parameter measured in the past 6-18 months which was not \> 125 mg/dl
* END-PDAC score \> 2

Exclusion Criteria

* Known or newly detected chronic pancreatitis
* Past history of pancreatic cancer
* History of steroid use
* Contraindications for EUS
Minimum Eligible Age

50 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Asian Institute of Gastroenterology, India

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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PDAC-NOD-001

Identifier Type: -

Identifier Source: org_study_id

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