Verily Watch Cardio (AF and ECG) Study

NCT ID: NCT06041373

Last Updated: 2023-12-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-30

Study Completion Date

2024-11-30

Brief Summary

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This study is designed to evaluate the performance of the Verily Watch Cardio for recording electrocardiogram (ECG) and photoplethysmography (PPG) signals and detecting suspected atrial fibrillation (AF) episodes, in a free-living environment, in participants at risk for having an AF event.

Detailed Description

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Conditions

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Atrial Fibrillation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Paroxysmal Atrial Fibrillation Patients

Verily Watch Cardio

Intervention Type DEVICE

The Verily Watch Cardio is an investigational wrist-worn wearable device containing multiple sensors to measure physiological and environmental metrics, including electrodes that enable a single-lead electrocardiogram (ECG) measurement and a photoplethysmogram (PPG) sensor to monitor for irregular pulses.

iRhythm Zio monitor

Intervention Type DEVICE

The iRhythm Zio monitor, the reference device, is an FDA-cleared single-patient use, continuously recording ECG monitor that can be worn for up to 14 days.

Schiller CARDIOVIT FT-1

Intervention Type DEVICE

The Schiller CARDIOVIT FT-1, the reference device, is an FDA-cleared portable 12-lead ECG machine capable of recording continuous standard 12-lead resting ECG for up to 4 minutes.

Interventions

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Verily Watch Cardio

The Verily Watch Cardio is an investigational wrist-worn wearable device containing multiple sensors to measure physiological and environmental metrics, including electrodes that enable a single-lead electrocardiogram (ECG) measurement and a photoplethysmogram (PPG) sensor to monitor for irregular pulses.

Intervention Type DEVICE

iRhythm Zio monitor

The iRhythm Zio monitor, the reference device, is an FDA-cleared single-patient use, continuously recording ECG monitor that can be worn for up to 14 days.

Intervention Type DEVICE

Schiller CARDIOVIT FT-1

The Schiller CARDIOVIT FT-1, the reference device, is an FDA-cleared portable 12-lead ECG machine capable of recording continuous standard 12-lead resting ECG for up to 4 minutes.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* At least 22 years old
* Able to read and speak English
* Participant understands the study requirements and is able and willing to sign written Informed Consent
* At risk of having an AF event, as determined by having a diagnosis of paroxysmal AF (PAF) and meeting one or more of the following:

1. Scheduled or to be scheduled to undergo AF ablation
2. AF burden of ≥25% in the 3 months prior to consent date as confirmed via an implantable loop recorder (ILR), holter monitor, or adhesive monitoring patch
3. CHA2DS2VASc score ≥3
4. Left atrial diameter ≥4.4 cm as confirmed by transthoracic echo (TTE) within one year of consent
* Without significant limitation in ability to participate in the study, in the opinion of the Investigator

Exclusion Criteria

* Have a pacemaker or implantable cardioverter defibrillator (ICD)
* Currently on class Ic or class III antiarrhythmic medication that has been successful in eliminating AF (no documented AF of more than 30 seconds since the initiation of the medication). Should be at least one week off medication.
* Had successful AF ablation (no documented AF of more than 30 seconds post procedure)
* Known severe allergy to nickel or metal jewelry
* Known allergic reaction to polyester, nylon, spandex, adhesives or hydrogels; or with family history of adhesive skin allergies
* Are diagnosed with persistent AF
* Have an implantable neuro-stimulator
* Currently wearing an ECG patch that prevents the use of the FDA-cleared wearable ECG patch, at the discretion of the Investigator.
* Have discolored wrists (e.g., tattoos, ink), at the discretion of the Investigator.
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Verily Life Sciences LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hamid Ghanbari, MD

Role: PRINCIPAL_INVESTIGATOR

Verily Life Sciences

Locations

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Colorado Heart and Vascular

Lakewood, Colorado, United States

Site Status

Ascension Providence Hospital

Southfield, Michigan, United States

Site Status

Wake Forest Medical Center

Winston-Salem, North Carolina, United States

Site Status

Countries

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United States

Other Identifiers

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104343

Identifier Type: -

Identifier Source: org_study_id