Trial Outcomes & Findings for Intergenerational Behavioral Intervention to Enhance Physical Activity in Older Adults at Risk for Alzheimer's Disease (NCT NCT06038643)
NCT ID: NCT06038643
Last Updated: 2025-07-09
Results Overview
This metric quantifies the change in the average number of steps taken each day, from the baseline period to the 4-week period. It is a marker of change in habitual ambulatory activity.
COMPLETED
NA
76 participants
4-week
2025-07-09
Participant Flow
Participant milestones
| Measure |
Intervention
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Overall Study
STARTED
|
36
|
40
|
|
Overall Study
COMPLETED
|
26
|
36
|
|
Overall Study
NOT COMPLETED
|
10
|
4
|
Reasons for withdrawal
| Measure |
Intervention
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Overall Study
Withdrawal by Subject
|
9
|
4
|
|
Overall Study
Excluded (not longer fulfilled enrollment criteria)
|
1
|
0
|
Baseline Characteristics
Intergenerational Behavioral Intervention to Enhance Physical Activity in Older Adults at Risk for Alzheimer's Disease
Baseline characteristics by cohort
| Measure |
Intervention
n=26 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=36 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
Total
n=62 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
4 Participants
n=5 Participants
|
4 Participants
n=7 Participants
|
8 Participants
n=5 Participants
|
|
Age, Categorical
>=65 years
|
22 Participants
n=5 Participants
|
32 Participants
n=7 Participants
|
54 Participants
n=5 Participants
|
|
Age, Continuous
|
69.81 years
STANDARD_DEVIATION 4.32 • n=5 Participants
|
70.97 years
STANDARD_DEVIATION 5.36 • n=7 Participants
|
70.48 years
STANDARD_DEVIATION 4.95 • n=5 Participants
|
|
Sex: Female, Male
Female
|
15 Participants
n=5 Participants
|
29 Participants
n=7 Participants
|
44 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
11 Participants
n=5 Participants
|
7 Participants
n=7 Participants
|
18 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
26 Participants
n=5 Participants
|
36 Participants
n=7 Participants
|
62 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Asian
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Black or African American
|
1 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
1 Participants
n=5 Participants
|
|
Race (NIH/OMB)
White
|
25 Participants
n=5 Participants
|
36 Participants
n=7 Participants
|
61 Participants
n=5 Participants
|
|
Race (NIH/OMB)
More than one race
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Region of Enrollment
Canada
|
26 participants
n=5 Participants
|
36 participants
n=7 Participants
|
62 participants
n=5 Participants
|
|
Years of Education
|
16.08 years
STANDARD_DEVIATION 3.07 • n=5 Participants
|
15.97 years
STANDARD_DEVIATION 3.55 • n=7 Participants
|
16.02 years
STANDARD_DEVIATION 3.33 • n=5 Participants
|
|
APOE4 genotype
APOE4 carriers
|
8 Participants
n=5 Participants
|
16 Participants
n=7 Participants
|
24 Participants
n=5 Participants
|
|
APOE4 genotype
APOE4 non-carriers
|
18 Participants
n=5 Participants
|
20 Participants
n=7 Participants
|
38 Participants
n=5 Participants
|
|
Body Mass Index
|
27.39 kg/m²
STANDARD_DEVIATION 5.03 • n=5 Participants
|
26.48 kg/m²
STANDARD_DEVIATION 4.56 • n=7 Participants
|
26.86 kg/m²
STANDARD_DEVIATION 4.74 • n=5 Participants
|
|
Alzheimer's Disease Risk
Lower Risk
|
18 Participants
n=5 Participants
|
19 Participants
n=7 Participants
|
37 Participants
n=5 Participants
|
|
Alzheimer's Disease Risk
Higher Risk
|
8 Participants
n=5 Participants
|
17 Participants
n=7 Participants
|
25 Participants
n=5 Participants
|
|
Mild Cognitive Impairment
Mild Cognitive Impairment
|
6 Participants
n=5 Participants
|
6 Participants
n=7 Participants
|
12 Participants
n=5 Participants
|
|
Mild Cognitive Impairment
Cognitively Unimpaired
|
20 Participants
n=5 Participants
|
30 Participants
n=7 Participants
|
50 Participants
n=5 Participants
|
|
Language
English
|
4 Participants
n=5 Participants
|
5 Participants
n=7 Participants
|
9 Participants
n=5 Participants
|
|
Language
French
|
22 Participants
n=5 Participants
|
31 Participants
n=7 Participants
|
53 Participants
n=5 Participants
|
|
Diastolic Blood Pressure
|
74.69 mmHg
STANDARD_DEVIATION 8.14 • n=5 Participants
|
74.42 mmHg
STANDARD_DEVIATION 6.58 • n=7 Participants
|
74.53 mmHg
STANDARD_DEVIATION 7.21 • n=5 Participants
|
|
Systolic Blood Pressure
|
125.81 mmHg
STANDARD_DEVIATION 16.36 • n=5 Participants
|
128.22 mmHg
STANDARD_DEVIATION 14.79 • n=7 Participants
|
127.21 mmHg
STANDARD_DEVIATION 15.38 • n=5 Participants
|
|
Steps per day
|
4224.77 Steps/day
STANDARD_DEVIATION 3149.72 • n=5 Participants
|
3881.07 Steps/day
STANDARD_DEVIATION 2978.81 • n=7 Participants
|
4025.20 Steps/day
STANDARD_DEVIATION 3051.94 • n=5 Participants
|
|
TMB Serial Reaction Time
|
364.73 seconds
STANDARD_DEVIATION 74.73 • n=5 Participants
|
388.13 seconds
STANDARD_DEVIATION 103.15 • n=7 Participants
|
378.54 seconds
STANDARD_DEVIATION 92.6 • n=5 Participants
|
|
TMB Choice Reaction Time
|
1208.83 seconds
STANDARD_DEVIATION 327.14 • n=5 Participants
|
1304.72 seconds
STANDARD_DEVIATION 639.63 • n=7 Participants
|
1265.42 seconds
STANDARD_DEVIATION 532.66 • n=5 Participants
|
|
Test my Brain Gradual Onset Continuous Performance Test (C)
|
0.38 Score on a scale
STANDARD_DEVIATION 0.43 • n=5 Participants
|
0.33 Score on a scale
STANDARD_DEVIATION 0.43 • n=7 Participants
|
0.35 Score on a scale
STANDARD_DEVIATION 0.43 • n=5 Participants
|
|
TMB Gradual Onset Continuous Performance Test (D)
|
2.71 scores on a scale
STANDARD_DEVIATION 0.77 • n=5 Participants
|
2.58 scores on a scale
STANDARD_DEVIATION 0.96 • n=7 Participants
|
2.64 scores on a scale
STANDARD_DEVIATION 0.88 • n=5 Participants
|
|
Test my Brain Matrix Reasoning
|
21.4 Score on a scale
STANDARD_DEVIATION 7.8 • n=5 Participants
|
21.14 Score on a scale
STANDARD_DEVIATION 6.8 • n=7 Participants
|
21.25 Score on a scale
STANDARD_DEVIATION 7.17 • n=5 Participants
|
|
Test my Brain Forward Digit Span
|
6.84 Score on a scale
STANDARD_DEVIATION 1.57 • n=5 Participants
|
6.0 Score on a scale
STANDARD_DEVIATION 1.99 • n=7 Participants
|
6.35 Score on a scale
STANDARD_DEVIATION 1.86 • n=5 Participants
|
|
Test my Brain Backwards Digit Span
|
5.28 Score on a scale
STANDARD_DEVIATION 1.88 • n=5 Participants
|
4.94 Score on a scale
STANDARD_DEVIATION 1.76 • n=7 Participants
|
5.08 Score on a scale
STANDARD_DEVIATION 1.81 • n=5 Participants
|
|
Test my Brain Visual Paired Associates Matching
|
14.5 Score on a scale
STANDARD_DEVIATION 4.3 • n=5 Participants
|
14.9 Score on a scale
STANDARD_DEVIATION 4.3 • n=7 Participants
|
14.73 Score on a scale
STANDARD_DEVIATION 4.3 • n=5 Participants
|
|
Test my Brain Digit Symbol Matching
|
36 Score on a scale
STANDARD_DEVIATION 6.95 • n=5 Participants
|
35.53 Score on a scale
STANDARD_DEVIATION 8.85 • n=7 Participants
|
35.72 Score on a scale
STANDARD_DEVIATION 8.06 • n=5 Participants
|
PRIMARY outcome
Timeframe: 4-weekPopulation: Participants included in the analysis were those who completed the study.
This metric quantifies the change in the average number of steps taken each day, from the baseline period to the 4-week period. It is a marker of change in habitual ambulatory activity.
Outcome measures
| Measure |
Intervention
n=26 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=36 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Total Step Count (Average Steps/Day)
|
5648.91 Steps/day
Standard Deviation 4033.49
|
3809.62 Steps/day
Standard Deviation 2833.25
|
SECONDARY outcome
Timeframe: 4 weeksThe Modified Differential Emotions Scale (mDES) Negative Emotions subscale measures the intensity of negative emotional experiences such as sadness, anger, fear, and shame. Possible scores: min. 0, max. 80 A higher score indicates greater emotional intensity or frequency of the emotions assessed.
Outcome measures
| Measure |
Intervention
n=23 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=31 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
The Modified Differential Emotions Scale (mDES) Negative Emotions
|
1.18 score
Standard Deviation 0.27
|
1.31 score
Standard Deviation 0.37
|
SECONDARY outcome
Timeframe: 4 weeksPopulation: Participants included in the analysis were those who completed the Generativity questionnaire.
This questionnaire measures generativity, which refers to the concern or desire individuals have to contribute to the well-being and development of future generations. Generative evaluates the extent to which individuals are motivated by generative concerns, including the desire to impact others and future generations; the Achievement subscale specifically captures the orientation toward personal goal attainment, mastery, and the pursuit of success as expressions of generativity. Scores for the generative achievement subscale ranged between 6 and 36, with higher scores indicating greater generative achievement.
Outcome measures
| Measure |
Intervention
n=21 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=29 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Generativity - Achievement
|
25.09 score
Standard Deviation 5.18
|
22.58 score
Standard Deviation 5.88
|
SECONDARY outcome
Timeframe: 4 weeksPopulation: The population included in the analysis were those who completed the Test My Brain Backward Digit Span subtest.
The TestMyBrain Digital Neuropsychology Toolkit Backwards Digit Span assesses working memory by requiring individuals to recall sequences of numbers in reverse order. In the backward version, the participant is shown a series of numbers in increasing length and asked to recall the numbers in reverse order. This is a test of short-term memory and working memory. This test was adapted from the Wechsler Adult Intelligence Scales. Scores go from 1 to 10. Higher scores are better.
Outcome measures
| Measure |
Intervention
n=24 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=28 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Test My Brain Digital Neuropsychology Toolkit - Backwards Digit Span
|
6.58 score
Standard Deviation 1.53
|
4.89 score
Standard Deviation 1.83
|
SECONDARY outcome
Timeframe: 4 weeksUniversity of California, Los Angeles (UCLA) Loneliness Scale. A higher average score indicates greater loneliness. Possible scores: min. 20, max. 80.
Outcome measures
| Measure |
Intervention
n=26 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=36 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Loneliness
|
53.71 score
Standard Deviation 23.89
|
44.87 score
Standard Deviation 19.25
|
SECONDARY outcome
Timeframe: 4 weeksThe Modified Differential Emotions Scale (mDES) Positive Emotions subscale measures the intensity of positive emotional experiences such as joy, gratitude, love, and hope. Possible scores: min. 0, max. 80 A higher score indicates greater emotional intensity or frequency of the emotions assessed.
Outcome measures
| Measure |
Intervention
n=23 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=31 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Modified Differential Emotions Scale (mDES) Positive Emotions
|
3.38 score
Standard Deviation 0.69
|
3.40 score
Standard Deviation 0.75
|
SECONDARY outcome
Timeframe: 4 weeksPopulation: Participants included in the analysis had completed the Generativity questionnaire.
The Generative Test measures generativity, which refers to the concern or desire individuals have to contribute to the well-being and development of future generations. The Desire subscale specifically assesses the emotional motivation and intrinsic longing to nurture, support, and positively impact others and future generations. Scores for the generative desire subscale ranged between 7 and 42, with higher scores indicating greater generative desire.
Outcome measures
| Measure |
Intervention
n=21 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=29 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Generativity Desire
|
31.67 score
Standard Deviation 6.13
|
29.72 score
Standard Deviation 7.05
|
SECONDARY outcome
Timeframe: 4 weeksPopulation: The population included in the analysis was those who completed the Test My Brain Choice Reaction Time.
The TestMyBrain Digital Neuropsychology Toolkit Choice Reaction Time task measures processing speed and attention by assessing how quickly individuals respond to different stimuli.
Outcome measures
| Measure |
Intervention
n=21 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=29 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Test My Brain Digital Neuropsychology Toolkit - Choice Reaction Time
|
1293.08 seconds
Standard Deviation 722.89
|
1136.67 seconds
Standard Deviation 389.61
|
SECONDARY outcome
Timeframe: 4 weeksPopulation: Participants included in the analysis had completed the Test My Brain Digit Symbol Matching subtest.
The TestMyBrain Digital Neuropsychology Toolkit Digit Symbol Matching task measures processing speed, attention, and visual-motor coordination by requiring rapid matching of symbols to corresponding numbers.
Outcome measures
| Measure |
Intervention
n=20 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=28 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Test My Brain Digital Neuropsychology Toolkit - Digit Symbol Matching
|
38.81 score
Standard Deviation 7.14
|
36.83 score
Standard Deviation 7.85
|
SECONDARY outcome
Timeframe: 4 weeksPopulation: The population included in the analysis was those who completed the Forward Digit Span.
The TestMyBrain Digital Neuropsychology Toolkit Forward Digit Span task measures short-term memory by requiring individuals to recall sequences of numbers in the order presented. In the forward version of TMB Digit Span, the participant is shown a series of numbers in increasing length and asked to recall the numbers in the order displayed. This is a test of short-term memory. This test was adapted from the Wechsler Adult Intelligence Scales. Scores go from 1 to 11. Higher scores are better.
Outcome measures
| Measure |
Intervention
n=21 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=28 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Test My Brain Digital Neuropsychology Toolkit - Forward Digit Span
|
6.91 score
Standard Deviation 1.57
|
6.18 score
Standard Deviation 1.81
|
SECONDARY outcome
Timeframe: 4 weeksPopulation: The population included in the analysis was those who completed the Test My Brain Gradual Onset Continuous Performance C subtest.
The TestMyBrain Digital Neuropsychology Toolkit Gradual Onset Continuous Performance Task measures sustained attention and inhibitory control by requiring individuals to detect target stimuli amid gradually changing non-targets. In this go/no-go test, the participant presses a button for each city image and withholds button presses for mountain images. This is a test of cognitive control, sustained attention, and response inhibition. Values can be from -1.5 to +1.5. Higher scores indicate better performance. The CPT.C score is a measure of response criterion, or how quickly and/or impulsively the participant tended to respond. Higher scores represent greater response impulsivity.
Outcome measures
| Measure |
Intervention
n=21 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=29 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Test My Brain Digital Neuropsychology Toolkit - Gradual Onset Continuous Performance C
|
0.45 score
Standard Deviation 0.25
|
0.40 score
Standard Deviation 0.36
|
SECONDARY outcome
Timeframe: 4 weeksPopulation: The population included in the analysis was those who completed the Test My Brain Gradual Onset Continuous Performance D subtest.
The TestMyBrain Digital Neuropsychology Toolkit Gradual Onset Continuous Performance Task (D) assesses sustained attention and response inhibition by requiring individuals to monitor and respond to target stimuli within a dynamic visual stream. In this go/no-go test, the participant presses a button for each city image and withholds button presses for mountain images. This is a test of cognitive control, sustained attention, and response inhibition. The CPT.D score is a measure of discrimination performance, related to how accurately the participant was able to respond to mountains and scenes. Higher scores represent better performance. Values can be from 1 to 4. Higher scores indicate better performance.
Outcome measures
| Measure |
Intervention
n=21 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=29 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Test My Brain Digital Neuropsychology Toolkit - Gradual Onset Continuous Performance D
|
2.80 score
Standard Deviation 0.65
|
2.87 score
Standard Deviation 0.91
|
SECONDARY outcome
Timeframe: 4 weeksPopulation: The population included in the analysis was those who completed the Test My Brain Matrix Reasoning.
The TestMyBrain Digital Neuropsychology Toolkit Matrix Reasoning task measures abstract reasoning and fluid intelligence by requiring individuals to identify patterns and complete visual matrices. In Test my Brain Matrix Reasoning, the participant selects which smaller image completes the pattern in the larger image. This is a test of visual reasoning and general cognitive ability. This test was adapted from the Wechsler Adult Intelligence Scales. Scores go from 2 to 32. Higher scores are better.
Outcome measures
| Measure |
Intervention
n=21 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=28 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Test My Brain Digital Neuropsychology Toolkit - Matrix Reasoning
|
22.18 score
Standard Deviation 6.52
|
22.58 score
Standard Deviation 6.04
|
SECONDARY outcome
Timeframe: 4 weeks.Population: The population included in the analysis was those who completed the Test My Brain Serial Reaction Time.
The TestMyBrain Digital Neuropsychology Toolkit Serial Reaction Time task measures implicit learning and motor sequence acquisition by assessing response speed to repeating and random stimulus patterns. In the TMB Serial Reaction Time task, higher scores in seconds (i.e., longer reaction times) indicate: Reduced processing speed Lower motor or attentional efficiency Weaker implicit sequence learning
Outcome measures
| Measure |
Intervention
n=21 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=29 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Test My Brain Digital Neuropsychology Toolkit - Serial Reaction Time
|
333.24 seconds
Standard Deviation 60.57
|
384.62 seconds
Standard Deviation 96.47
|
SECONDARY outcome
Timeframe: 4 weeksPopulation: The population included in the analysis was those who completed the Test My Brain Visual Paired Associates.
The TestMyBrain Digital Neuropsychology Toolkit Visual Paired Associates task measures associative memory by requiring individuals to learn and recall visual symbol pairs. In this test, the participant memorizes a set of picture pairs. Then, after completing TMB Digit Symbol Matching (90 sec), the participant selects which pictures were paired together. TMB Visual PA is a test of visual episodic memory. In TMB Digit SM, the participant matches as many number/symbol pairs as possible in 90 seconds. This is a test of processing speed. Scores go from 4 to 23. Higher scores are better.
Outcome measures
| Measure |
Intervention
n=21 Participants
Social motivation intervention, self-transcendence daily messages, and daily accelerometry.
Motivational behavioural intervention and daily activities monitoring: Social motivation manipulation, self-transcendence daily messaging, and daily activities monitoring through accelerometry. Participants in this arm will have a study partner who receives daily feedback on the main participant's daily step count.
|
Active Control
n=28 Participants
Daily accelerometry.
Active Control: Daily activities monitored through accelerometry.
|
|---|---|---|
|
Test My Brain Digital Neuropsychology Toolkit - Visual Paired Associates
|
16.2 score
Standard Deviation 4.41
|
16.3 score
Standard Deviation 3.93
|
Adverse Events
Intervention
Active Control
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place