The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

NCT ID: NCT06030063

Last Updated: 2025-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-02-22

Study Completion Date

2028-12-31

Brief Summary

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The SOAP registry is a prospective, multicenter, electronic registry. The goal is to investigate the indications, mode of airway management, predisposing factors, and obstetric and anesthetic outcomes of pregnant patients who receive general anesthesia for cesarean delivery.

Detailed Description

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This is a central repository with data from 25-40 participating SOAP institutions/hospitals.

The primary and secondary aims of this study are as follows:

1. To determine the institutional factors associated with rates of general anesthesia for cesarean delivery
2. To perform a descriptive analysis of characteristics of general anesthesia for cesarean delivery cases
3. To determine maternal and anesthetic predictors of difficult intubation

Data will be collected from each participating SOAP institution. Institutional data will include information on the characteristics of the institution such as maternal level of care, numbers of lives birth, staffing models, etc. This data will be collected prior to subjects being enrolled into the registry and again at the registry closure to look at intuitional changes over time.

Inclusion into the registry is based on the following criteria:

1. Pregnant women who have had a general anesthetic for Cesarean delivery
2. 15-55 years old

The general anesthesia registry will collect data on subject demographics in a deidentified manner, including characteristics of the birth and delivery, gestational age, maternal morbidities, and anesthetic management.

The granular detail requested in the registry database will help to better understand the nuances of how and why decisions are made about proceeding with general anesthesia in these cases, and once done, how to implement this clinical course. As not all of these data points are routinely recorded in the medical record, optimal data capture requires the treating anesthesiologist to complete the registry entry as soon as possible after conclusion of patient care.

Data will be collected for approximately 5 years and maintained indefinitely. Data is entered into a Yale REDCap registry and will not contain subject identifiers. An estimated 5000 subjects will be enrolled into the data repository. This is based on a published report of 45 institutions' data investigating a subtopic of this question (15 years yielding 15,000 general anesthetics).

Conditions

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General Anesthesia Cesarean Delivery

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

-Pregnant women aged 15-55 who have had a general anesthetic for Cesarean delivery
Minimum Eligible Age

15 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Yale University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Lisa Leffert, MD

Role: PRINCIPAL_INVESTIGATOR

Yale Univesrity

Locations

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University of Arkansas

Little Rock, Arkansas, United States

Site Status RECRUITING

University of California San Francisco

San Francisco, California, United States

Site Status RECRUITING

Stanford University

Stanford, California, United States

Site Status RECRUITING

University of Colorado Hospital

Arvada, Colorado, United States

Site Status RECRUITING

Yale University

New Haven, Connecticut, United States

Site Status RECRUITING

University of Florida

Gainesville, Florida, United States

Site Status RECRUITING

St Lukes Anesthesia Associates of Boise

Boise, Idaho, United States

Site Status RECRUITING

University of Chicago Medical Center

Chicago, Illinois, United States

Site Status RECRUITING

Indiana University

Indianapolis, Indiana, United States

Site Status RECRUITING

University of Iowa

Iowa City, Iowa, United States

Site Status RECRUITING

University of Kansas Health System

Kansas City, Kansas, United States

Site Status RECRUITING

University of Maryland School of Medicine

Baltimore, Maryland, United States

Site Status RECRUITING

Brigham & Women's Hospital

Boston, Massachusetts, United States

Site Status RECRUITING

Boston Medical Center

Boston, Massachusetts, United States

Site Status RECRUITING

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Site Status RECRUITING

Mayo Clinic

Rochester, Minnesota, United States

Site Status RECRUITING

Mercy Hospital St. Louis

St Louis, Missouri, United States

Site Status RECRUITING

Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, United States

Site Status RECRUITING

University of New Mexico

Albuquerque, New Mexico, United States

Site Status RECRUITING

Albany Medical Center

Albany, New York, United States

Site Status RECRUITING

Northwell Health

Manhasset, New York, United States

Site Status RECRUITING

Icahn School of Medicine at Mount Sinai

New York, New York, United States

Site Status RECRUITING

Renaissance School of Medicine Stony Brook University

Stony Brook, New York, United States

Site Status RECRUITING

Duke University Medical Center

Durham, North Carolina, United States

Site Status RECRUITING

Atrium Health Wake Forest Baptist Medical Center

Winston-Salem, North Carolina, United States

Site Status RECRUITING

University o Cincinnati

Cincinnati, Ohio, United States

Site Status RECRUITING

Ohio State University/Wexner Medical Center

Columbus, Ohio, United States

Site Status RECRUITING

Oregon Health & Science University

Portland, Oregon, United States

Site Status RECRUITING

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Site Status RECRUITING

Medical University of South Carolina

Charleston, South Carolina, United States

Site Status RECRUITING

Vanderbilt University Medical Center

Nashville, Tennessee, United States

Site Status RECRUITING

University of Texas-Houston

Houston, Texas, United States

Site Status RECRUITING

Baylor Scott & White Medical Center

Temple, Texas, United States

Site Status RECRUITING

University of Virginia

Charlottesville, Virginia, United States

Site Status RECRUITING

Royal Columbian Hospital & University of British Columbia

New Westminster, , Canada

Site Status RECRUITING

Countries

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United States Canada

Central Contacts

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Lisa Leffert, MD

Role: CONTACT

Phone: (203)785-4304

Email: [email protected]

Facility Contacts

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Jessica Sheeran, MD

Role: primary

Michelle Mozel

Role: primary

Nadir Sharawi, MD

Role: primary

Jillene Sturgess-Daprato

Role: primary

Mina Michel

Role: primary

Cristina Wood, MD

Role: primary

Ricarda Tomlin

Role: primary

Amy Gunnett

Role: primary

Allen Botimer, MD

Role: primary

Somayeh Mohammadi

Role: primary

Angie Plummer

Role: primary

Cynthia Wong

Role: primary

Grace Shih, MD

Role: primary

Shobana Bharadwaj, MD

Role: primary

Noor Reel

Role: primary

Mark Norris, MD

Role: primary

Yunping Li, MD

Role: primary

Emily Sharpe, MD

Role: primary

Amber Benhardt

Role: primary

Johanna Cobb, MD

Role: primary

Emily McQuaid-Hanson, MD

Role: primary

Mantab Sheikh

Role: primary

Andrea Ruggerio

Role: primary

Nakiyah Knibbs, MD

Role: primary

Ayesha Khan

Role: primary

Ashraf Habib, MD

Role: primary

Lynne Harris

Role: primary

Andrea Girnius, MD

Role: primary

Kasey Fiorini, MD

Role: primary

Sarah Feller

Role: primary

Alexandra Nicholas, MD

Role: primary

Haley Nitchie

Role: primary

Holly Ende, MD

Role: primary

Barbara Orlando, MD

Role: primary

Michael Hofkamp

Role: primary

Other Identifiers

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2000033638

Identifier Type: -

Identifier Source: org_study_id