Trial Outcomes & Findings for Multiplexing Prism Fitting for Field Expansion of Monocular Vision (NCT NCT06027216)

NCT ID: NCT06027216

Last Updated: 2025-05-08

Results Overview

Field expansion is calculated based on the difference of the maximum field of view on the nasal side of the seeing/functioning eye (same side as the blind eye) with and without multiplexing prism.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

30 participants

Primary outcome timeframe

Visit 2 of Study (approximately 2-3 weeks after 1st Visit)

Results posted on

2025-05-08

Participant Flow

Participant milestones

Participant milestones
Measure
Enrolled Participants for Multiplexing Prism
Of the 30 enrolled participants, 22 met the inclusion criteria and were prescribed with the multiplexing prism.
Overall Study
STARTED
30
Overall Study
COMPLETED
22
Overall Study
NOT COMPLETED
8

Reasons for withdrawal

Reasons for withdrawal
Measure
Enrolled Participants for Multiplexing Prism
Of the 30 enrolled participants, 22 met the inclusion criteria and were prescribed with the multiplexing prism.
Overall Study
Did not qualify
8

Baseline Characteristics

Multiplexing Prism Fitting for Field Expansion of Monocular Vision

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Patient's Demography
n=22 Participants
Adult individual with acquired monocular vision (seeing with one eye)
Age, Continuous
56 years
STANDARD_DEVIATION 19 • n=5 Participants
Sex: Female, Male
Female
12 Participants
n=5 Participants
Sex: Female, Male
Male
10 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
1 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
21 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
1 Participants
n=5 Participants
Race (NIH/OMB)
White
21 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Nasal Visual Field of the Seeing/Functioning Eye
55 degree
STANDARD_DEVIATION 4 • n=5 Participants

PRIMARY outcome

Timeframe: Visit 2 of Study (approximately 2-3 weeks after 1st Visit)

Field expansion is calculated based on the difference of the maximum field of view on the nasal side of the seeing/functioning eye (same side as the blind eye) with and without multiplexing prism.

Outcome measures

Outcome measures
Measure
Amount of Visual Field Expansion
n=22 Participants
The maximum field of view on the nasal side (same side as the blind eye) of the participants with and without the multiplexing prism is measured. An increase in visual field indicates field expansion/gain.
Gain in Visual Field With the Multiplexing Prism
24 degrees
Standard Deviation 4

SECONDARY outcome

Timeframe: Visit 2 of Study (approximately 2-3 weeks after 1st Visit)

The farthest extent of the nasal visual field with the multiplexing prism placed in front of the seeing eye.

Outcome measures

Outcome measures
Measure
Amount of Visual Field Expansion
n=22 Participants
The maximum field of view on the nasal side (same side as the blind eye) of the participants with and without the multiplexing prism is measured. An increase in visual field indicates field expansion/gain.
Maximum Extent of Nasal Visual Field With the Multiplexing Prism
79 degrees
Standard Deviation 5

Adverse Events

Patient's Demography

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Eli Peli

Schepens Eye Research Institute, Mass Eye and Ear

Phone: 617-912-2597

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place