Cyclin D1 as a Prognostic Factor in Multiple Myeloma and Its Association With the Immunological Prognostic Factor PDL1 and Clinical and Biochemical Lab Tests

NCT ID: NCT05995808

Last Updated: 2023-08-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-30

Study Completion Date

2025-08-31

Brief Summary

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Multiple myeloma (MM) is the most common bone marrow malignancy of terminally differentiated plasma cells. It accounts for about 1% of all malignant diseases and 10% of haematological malignancies and takes the second place after non-Hodgkin lymphoma .

There are some serological and clinical criteria that help to detect the stage of MM and predict the patients' prognosis. These criteria include the level of M protein, calcium, haemoglobin, albumin, creatinine, β2-microglobulin and glomerular filtration rate (GFR).

Detailed Description

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Conditions

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Multiple Myeloma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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diagnostic group

Group Type EXPERIMENTAL

Bone marow biopsy and aspiration

Intervention Type PROCEDURE

Bone marrow biopsy and biopsy aspiration

biochemical and heamatological tests

Intervention Type DIAGNOSTIC_TEST

complete blood count ,serum urea and creatinine

Interventions

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Bone marow biopsy and aspiration

Bone marrow biopsy and biopsy aspiration

Intervention Type PROCEDURE

biochemical and heamatological tests

complete blood count ,serum urea and creatinine

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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complete blood count ,urea and creatinine in serum

Eligibility Criteria

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Inclusion Criteria

1. Patients older than 18 year with newly diagnosed MM.
2. Approval to sign an informed written consent.

Exclusion Criteria

* 1\. Patient younger than 18 years. 2.Refusal to sign an informed written consent.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Fainan Khaled Ahmed

clinical pathology specialist

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Fainan K EL Kady, spcialist

Role: CONTACT

01063017967

Douaa M Sayed, professor

Role: CONTACT

Other Identifiers

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Soh-Med-23-07-02MD

Identifier Type: -

Identifier Source: org_study_id

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