Trial Outcomes & Findings for An eHealth Intervention to Increase Depression Treatment Initiation and Adherence Among Veterans Referred for Mental Health Services (NCT NCT05990075)
NCT ID: NCT05990075
Last Updated: 2026-01-20
Results Overview
Intervention enrollment was measured by completion of baseline survey which entailed patients' explicit agreement to participate in the intervention.
ACTIVE_NOT_RECRUITING
NA
47 participants
Up to 30 weeks.
2026-01-20
Participant Flow
Participants were recruited based on physician referrals to specialty mental health clinics for depressive disorders and depressive symptoms between September 2023-September 2024. Prior to enrollment, participant clinical charts were screened.
Of those who met inclusion criteria, 47 patients agreed to participation and enrolled in the study.
Participant milestones
| Measure |
Self-monitoring
This research study will evaluate a self-monitoring intervention to increase awareness, provide support, and promote motivation to initiate treatment after referral to mental health. The proposed intervention is a user-driven program delivered online and by mobile text. This will be initially piloted for acceptability among Veterans referred to mental health service for depression treatment.
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|---|---|
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Overall Study
STARTED
|
47
|
|
Overall Study
COMPLETED
|
47
|
|
Overall Study
NOT COMPLETED
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
An eHealth Intervention to Increase Depression Treatment Initiation and Adherence Among Veterans Referred for Mental Health Services
Baseline characteristics by cohort
| Measure |
Self-monitoring
n=47 Participants
This research study will evaluate a self-monitoring intervention to increase awareness, provide support, and promote motivation to initiate treatment after referral to mental health. The proposed intervention is a user-driven program delivered online and by mobile text. This will be initially piloted for acceptability among Veterans referred to mental health service for depression treatment.
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|---|---|
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Age, Continuous
|
43 years
STANDARD_DEVIATION 9 • n=37 Participants
|
|
Sex: Female, Male
Female
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25 Participants
n=37 Participants
|
|
Sex: Female, Male
Male
|
22 Participants
n=37 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=37 Participants
|
|
Race (NIH/OMB)
Asian
|
0 Participants
n=37 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
1 Participants
n=37 Participants
|
|
Race (NIH/OMB)
Black or African American
|
14 Participants
n=37 Participants
|
|
Race (NIH/OMB)
White
|
22 Participants
n=37 Participants
|
|
Race (NIH/OMB)
More than one race
|
0 Participants
n=37 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
10 Participants
n=37 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
10 Participants
n=37 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
33 Participants
n=37 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
4 Participants
n=37 Participants
|
|
Marital status
Divorced
|
11 Participants
n=37 Participants
|
|
Marital status
Married
|
21 Participants
n=37 Participants
|
|
Marital status
Never Married
|
11 Participants
n=37 Participants
|
|
Marital status
Separated
|
3 Participants
n=37 Participants
|
|
Marital status
Unknown
|
1 Participants
n=37 Participants
|
|
Service Connected (%)
0%
|
4 Participants
n=37 Participants
|
|
Service Connected (%)
10-50%
|
5 Participants
n=37 Participants
|
|
Service Connected (%)
60-90%
|
17 Participants
n=37 Participants
|
|
Service Connected (%)
100%
|
21 Participants
n=37 Participants
|
|
Service Connected for Mental Health
Yes
|
33 Participants
n=37 Participants
|
|
Service Connected for Mental Health
No
|
14 Participants
n=37 Participants
|
|
Barriers to Accessing Care Evaluation (BACE)
Stigma related barriers
|
0.64 Units on a scale
STANDARD_DEVIATION 0.50 • n=37 Participants
|
|
Barriers to Accessing Care Evaluation (BACE)
Access and practical barriers
|
1.04 Units on a scale
STANDARD_DEVIATION 0.50 • n=37 Participants
|
|
Affective Control Scale (ACS)
Fear of anger
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4.20 Units on a scale
STANDARD_DEVIATION 1.11 • n=37 Participants
|
|
Affective Control Scale (ACS)
Fear of positive emotions
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3.47 Units on a scale
STANDARD_DEVIATION 0.91 • n=37 Participants
|
|
Affective Control Scale (ACS)
Fear of depression
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4.19 Units on a scale
STANDARD_DEVIATION 0.97 • n=37 Participants
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|
Affective Control Scale (ACS)
Fear of anxiety
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4.39 Units on a scale
STANDARD_DEVIATION 1.05 • n=37 Participants
|
|
Patient Health Questionnaire 8 (PHQ8)
|
15.34 Units on a scale
STANDARD_DEVIATION 5.4 • n=37 Participants
|
PRIMARY outcome
Timeframe: Up to 30 weeks.Population: The denominator for this analysis were participants who were pre-screened, met study criteria, and were invited to participate in the intervention.
Intervention enrollment was measured by completion of baseline survey which entailed patients' explicit agreement to participate in the intervention.
Outcome measures
| Measure |
Self-monitoring
n=270 Participants
This research study will evaluate a self-monitoring intervention to increase awareness, provide support, and promote motivation to initiate treatment after referral to mental health. The proposed intervention is a user-driven program delivered online and by mobile text. This will be initially piloted for acceptability among Veterans referred to mental health service for depression treatment.
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|---|---|
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Incidence of Intervention Enrollment as Assessed by Completion of Baseline Survey.
|
47 Participants
|
PRIMARY outcome
Timeframe: Immediately after intervention completion.Mental Health Link asks patients to report on 24 hour positive and negative events, emotions, and depression symptoms.
Outcome measures
| Measure |
Self-monitoring
n=47 Participants
This research study will evaluate a self-monitoring intervention to increase awareness, provide support, and promote motivation to initiate treatment after referral to mental health. The proposed intervention is a user-driven program delivered online and by mobile text. This will be initially piloted for acceptability among Veterans referred to mental health service for depression treatment.
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|---|---|
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Percent Patients With Completed Tasks as Measured by Mental Health Link.
Engagement with intervention
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47 Participants
|
|
Percent Patients With Completed Tasks as Measured by Mental Health Link.
> 50% engagement rate
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25 Participants
|
OTHER_PRE_SPECIFIED outcome
Timeframe: Immediately after intervention, up to 30 weeks.Population: Denominator for treatment adherence is number of patients who initiated treatment.
The investigators will evaluate % mental health treatment initiation relative to the general population in the same clinics. This measure is experimental given that efficacy is not yet the focus of this work given its preliminary stage. Treatment initiation is defined as initial mental health appointment being completed. Treatment adherence is defined as continuing treatment past initiation.
Outcome measures
| Measure |
Self-monitoring
n=47 Participants
This research study will evaluate a self-monitoring intervention to increase awareness, provide support, and promote motivation to initiate treatment after referral to mental health. The proposed intervention is a user-driven program delivered online and by mobile text. This will be initially piloted for acceptability among Veterans referred to mental health service for depression treatment.
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|---|---|
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Efficacy of Intervention as Assessed by Rate of Depression Treatment Initiation and Adherence
Treatment initiation
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32 Participants
|
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Efficacy of Intervention as Assessed by Rate of Depression Treatment Initiation and Adherence
Treatment adherence (1+ sessions)
|
28 Participants
|
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Efficacy of Intervention as Assessed by Rate of Depression Treatment Initiation and Adherence
Treatment adherence (4+ sessions)
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18 Participants
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Adverse Events
Self-monitoring
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place