Trial Outcomes & Findings for Comparing the Effects of Upper and Lower Body Resistance Training on Pain Sensitivity (NCT NCT05985382)
NCT ID: NCT05985382
Last Updated: 2025-03-04
Results Overview
For pressure pain threshold, an algometer was gradually increased until the sensation changed from pressure to pain. Pressure at threshold was recorded in kilopascals.
COMPLETED
NA
30 participants
Pressure pain threshold will be applied to the quadriceps immediately after each exercise.
2025-03-04
Participant Flow
Participant milestones
| Measure |
Lower Then Upper Body Resistance Exercise
Participants will perform a lower body resistance exercise first then upper body resistance exercise. This is a cross-over design.
Lower Body Resistance Exercise: Participants will complete a leg extension exercise with weight equivalent to 75% of their estimated 1-repetition maximum 3 sets, 10 repetitions.
Participants will perform a shoulder press with weight that is 75% of their estimated 1-repetition maximum (1-RM) for 3 sets of 10 repetitions.
Upper Body Resistance Exercise: Participants will complete a leg extension exercise with weight equivalent to 75% of their estimated 1-repetition maximum 3 sets, 10 repetitions.
|
Upper Then Lower Body Resistance Exercise
Participants will perform a upper body resistance exercise first then upper body resistance exercise. This is a cross-over design.
Upper Body Resistance Exercise: Participants will complete a leg extension exercise with weight equivalent to 75% of their estimated 1-repetition maximum 3 sets, 10 repetitions.
Lower Body Resistance Exercise: Participants will complete a leg extension exercise with weight equivalent to 75% of their estimated 1-repetition maximum 3 sets, 10 repetitions.
Participants will perform a shoulder press with weight that is 75% of their estimated 1-repetition maximum (1-RM) for 3 sets of 10 repetitions.
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|---|---|---|
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Overall Study
STARTED
|
15
|
15
|
|
Overall Study
COMPLETED
|
15
|
15
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Comparing the Effects of Upper and Lower Body Resistance Training on Pain Sensitivity
Baseline characteristics by cohort
| Measure |
Upper and Lower Body Resistance Exercise
n=30 Participants
All participants will perform a leg extension exercise with weight that is 75% of their estimated 1-repetition maximum (1-RM) for 3 sets of 10 repetitions.
Lower Body Resistance Exercise: Participants will complete a leg extension exercise with weight equivalent to 75% of their estimated 1-repetition maximum 3 sets, 10 repetitions.
Participants will perform a shoulder press with weight that is 75% of their estimated 1-repetition maximum (1-RM) for 3 sets of 10 repetitions.
Upper Body Resistance Exercise: Participants will complete a leg extension exercise with weight equivalent to 75% of their estimated 1-repetition maximum 3 sets, 10 repetitions.
|
|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=5 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
30 Participants
n=5 Participants
|
|
Age, Categorical
>=65 years
|
0 Participants
n=5 Participants
|
|
Age, Continuous
|
21 years
STANDARD_DEVIATION 4 • n=5 Participants
|
|
Sex: Female, Male
Female
|
21 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
9 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
9 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
21 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
|
Region of Enrollment
United States
|
30 Participants
n=5 Participants
|
PRIMARY outcome
Timeframe: Pressure pain threshold will be applied to the quadriceps immediately after each exercise.For pressure pain threshold, an algometer was gradually increased until the sensation changed from pressure to pain. Pressure at threshold was recorded in kilopascals.
Outcome measures
| Measure |
Lower Body Resistance Exercise
n=30 Participants
Participants will perform a leg extension exercise with weight that is 75% of their estimated 1-repetition maximum (1-RM) for 3 sets of 10 repetitions.
Lower Body Resistance Exercise: Participants will complete a leg extension exercise with weight equivalent to 75% of their estimated 1-repetition maximum 3 sets, 10 repetitions.
|
Upper Body Resistance Exercise
n=30 Participants
Participants will perform a shoulder press with weight that is 75% of their estimated 1-repetition maximum (1-RM) for 3 sets of 10 repetitions.
|
|---|---|---|
|
Lower Body Resistance Exercise
|
594.10 kilopascals
Standard Deviation 234.74
|
572.54 kilopascals
Standard Deviation 249.87
|
SECONDARY outcome
Timeframe: Heat Pain Threshold will be applied over the quadriceps before and after the exercise.All participants completed Heat Pain Threshold. For heat pain threshold, a thermode will gradually warm up from 32 degrees Celsius until the participant reports the sensation changes from comfortable warmth to slightly unpleasant pain. The temperature at threshold will be recorded.
Outcome measures
| Measure |
Lower Body Resistance Exercise
n=30 Participants
Participants will perform a leg extension exercise with weight that is 75% of their estimated 1-repetition maximum (1-RM) for 3 sets of 10 repetitions.
Lower Body Resistance Exercise: Participants will complete a leg extension exercise with weight equivalent to 75% of their estimated 1-repetition maximum 3 sets, 10 repetitions.
|
Upper Body Resistance Exercise
n=30 Participants
Participants will perform a shoulder press with weight that is 75% of their estimated 1-repetition maximum (1-RM) for 3 sets of 10 repetitions.
|
|---|---|---|
|
Heat Pain Threshold
|
43.75 Degrees Celsius
Standard Deviation 3.27
|
43.56 Degrees Celsius
Standard Deviation 3.18
|
Adverse Events
Lower Body Then Upper Body Resistance Exercise
Upper Body Then Lower Body Resistance Exercise
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place