Trial Outcomes & Findings for Pilot Testing a Virtual Mindfulness-Based Intervention to Improve Veterans' Health (NCT NCT05975008)

NCT ID: NCT05975008

Last Updated: 2026-01-28

Results Overview

The Military to Civilian Questionnaire (M2C-Q) is an empirically validated self-report scale that measures general difficulty in readjusting to civilian life by assessing important indicators of reintegration challenges over the past 30 days including social/health behaviors, specifically interpersonal relationships; productivity at school, work, or home; community participation; self-care; leisure; and perceived meaning in life. Scores can range from 0-64. Higher scores indicate greater reintegration difficulty.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

36 participants

Primary outcome timeframe

30 days

Results posted on

2026-01-28

Participant Flow

The investigators requested a list of Veterans and their contact information based on the study inclusion criteria via CDW. The research assistant mailed a recruitment brochure and letter to eligible Veterans. Study staff contacted eligible Veteran participants by phone and/or email to recruit them for the study. Veterans who enrolled were emailed using VA compliant methods. Word-of-mouth and snowballing techniques were also used to identify eligible Veteran participants.

Some participants were lost to follow-up (i.e., could not be contacted after enrolling in the study) or withdrew due to scheduling conflicts.

Participant milestones

Participant milestones
Measure
RECLAIM/Intervention
Veteran participants randomized to the intervention group. Eight sessions of a brief mindfulness-based intervention that meets weekly in a virtual setting.
Psychoeducation Materials Only/Control Group
The investigators will use a psychoeducation-only control group. They will only receive psychoeducational materials (e.g., suggested readings, podcasts, blogs). These are the same materials that the intervention arm participants will receive.
Overall Study
STARTED
18
18
Overall Study
COMPLETED
8
7
Overall Study
NOT COMPLETED
10
11

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Pilot Testing a Virtual Mindfulness-Based Intervention to Improve Veterans' Health

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
RECLAIM/Intervention
n=18 Participants
Veteran participants randomized to the intervention group. Eight sessions of a brief mindfulness-based intervention that meets weekly in a virtual setting.
Psychoeducation Materials Only/Control Group
n=18 Participants
The investigators will use a psychoeducation-only control group. They will only receive psychoeducational materials (e.g., suggested readings, podcasts, blogs). These are the same materials that the intervention arm participants will receive.
Total
n=36 Participants
Total of all reporting groups
Age, Continuous
31.1 Years
STANDARD_DEVIATION 7.3 • n=158 Participants
30 Years
STANDARD_DEVIATION 6 • n=157 Participants
30.5 Years
STANDARD_DEVIATION 6.6 • n=315 Participants
Sex/Gender, Customized
Gender · Male
11 Participants
n=158 Participants
14 Participants
n=157 Participants
25 Participants
n=315 Participants
Sex/Gender, Customized
Gender · Female
6 Participants
n=158 Participants
4 Participants
n=157 Participants
10 Participants
n=315 Participants
Sex/Gender, Customized
Gender · Not disclosed
1 Participants
n=158 Participants
0 Participants
n=157 Participants
1 Participants
n=315 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
1 Participants
n=158 Participants
5 Participants
n=157 Participants
6 Participants
n=315 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
17 Participants
n=158 Participants
13 Participants
n=157 Participants
30 Participants
n=315 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=158 Participants
0 Participants
n=157 Participants
0 Participants
n=315 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=158 Participants
0 Participants
n=157 Participants
0 Participants
n=315 Participants
Race (NIH/OMB)
Asian
0 Participants
n=158 Participants
1 Participants
n=157 Participants
1 Participants
n=315 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=158 Participants
0 Participants
n=157 Participants
0 Participants
n=315 Participants
Race (NIH/OMB)
Black or African American
3 Participants
n=158 Participants
2 Participants
n=157 Participants
5 Participants
n=315 Participants
Race (NIH/OMB)
White
12 Participants
n=158 Participants
14 Participants
n=157 Participants
26 Participants
n=315 Participants
Race (NIH/OMB)
More than one race
3 Participants
n=158 Participants
0 Participants
n=157 Participants
3 Participants
n=315 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=158 Participants
1 Participants
n=157 Participants
1 Participants
n=315 Participants
Military to Civilian Questionnaire
36.3 score on a scale
STANDARD_DEVIATION 12.7 • n=158 Participants
33.3 score on a scale
STANDARD_DEVIATION 7.5 • n=157 Participants
34.9 score on a scale
STANDARD_DEVIATION 10.4 • n=315 Participants
Patient Health Questionnaire
15.9 score on a scale
STANDARD_DEVIATION 5.8 • n=158 Participants
13.6 score on a scale
STANDARD_DEVIATION 3.6 • n=157 Participants
14.3 score on a scale
STANDARD_DEVIATION 4.8 • n=315 Participants
Generalized Anxiety Disorder Scale
12.6 score on a scale
STANDARD_DEVIATION 4.4 • n=158 Participants
14.1 score on a scale
STANDARD_DEVIATION 5.2 • n=157 Participants
13.5 score on a scale
STANDARD_DEVIATION 4.2 • n=315 Participants
Pain, Enjoyment, General Activity
4.4 score on a scale
STANDARD_DEVIATION 2.7 • n=158 Participants
5.1 score on a scale
STANDARD_DEVIATION 2.1 • n=157 Participants
4.7 score on a scale
STANDARD_DEVIATION 2.4 • n=315 Participants
Five Facet Mindfulness Questionnaire
Facet of Mindfulness: Observing
11 score on a scale
STANDARD_DEVIATION 4.1 • n=158 Participants
9.0 score on a scale
STANDARD_DEVIATION 3.5 • n=157 Participants
10.1 score on a scale
STANDARD_DEVIATION 3.9 • n=315 Participants
Five Facet Mindfulness Questionnaire
Facet of Mindfulness: Describing
9.5 score on a scale
STANDARD_DEVIATION 2.9 • n=158 Participants
8.4 score on a scale
STANDARD_DEVIATION 2.2 • n=157 Participants
9 score on a scale
STANDARD_DEVIATION 2.6 • n=315 Participants
Five Facet Mindfulness Questionnaire
Facet of Mindfulness: Awareness
10.5 score on a scale
STANDARD_DEVIATION 2 • n=158 Participants
7.7 score on a scale
STANDARD_DEVIATION 2.6 • n=157 Participants
9.2 score on a scale
STANDARD_DEVIATION 2.6 • n=315 Participants
Five Facet Mindfulness Questionnaire
Facet of Mindfulness: Non-judging
9 score on a scale
STANDARD_DEVIATION 3.7 • n=158 Participants
9.3 score on a scale
STANDARD_DEVIATION 1.3 • n=157 Participants
9.1 score on a scale
STANDARD_DEVIATION 2.7 • n=315 Participants
Five Facet Mindfulness Questionnaire
Facet of Mindfulness: Non-reacting
8.1 score on a scale
STANDARD_DEVIATION 2.5 • n=158 Participants
9.1 score on a scale
STANDARD_DEVIATION 3.6 • n=157 Participants
8.6 score on a scale
STANDARD_DEVIATION 3 • n=315 Participants

PRIMARY outcome

Timeframe: 30 days

The Military to Civilian Questionnaire (M2C-Q) is an empirically validated self-report scale that measures general difficulty in readjusting to civilian life by assessing important indicators of reintegration challenges over the past 30 days including social/health behaviors, specifically interpersonal relationships; productivity at school, work, or home; community participation; self-care; leisure; and perceived meaning in life. Scores can range from 0-64. Higher scores indicate greater reintegration difficulty.

Outcome measures

Outcome measures
Measure
RECLAIM/Intervention
n=8 Participants
Veteran participants randomized to the intervention group. Eight sessions of a brief mindfulness-based intervention that meets weekly in a virtual setting.
Psychoeducation Materials Only/Control Group
n=7 Participants
The investigators will use a psychoeducation-only control group. They will only receive psychoeducational materials (e.g., suggested readings, podcasts, blogs). These are the same materials that the intervention arm participants will receive.
Military to Civilian Questionnaire
27 score on a scale
Standard Deviation 14.1
24.7 score on a scale
Standard Deviation 8.4

SECONDARY outcome

Timeframe: 2 weeks

The Patient Health Questionnaire (PHQ-9) is a reliable and valid 9-item measure of depression severity used to screen, diagnose, monitor, and measure the severity of depression. Scores can range from 0-27 and higher scores indicate greater depression severity.

Outcome measures

Outcome measures
Measure
RECLAIM/Intervention
n=8 Participants
Veteran participants randomized to the intervention group. Eight sessions of a brief mindfulness-based intervention that meets weekly in a virtual setting.
Psychoeducation Materials Only/Control Group
n=7 Participants
The investigators will use a psychoeducation-only control group. They will only receive psychoeducational materials (e.g., suggested readings, podcasts, blogs). These are the same materials that the intervention arm participants will receive.
Patient Health Questionnaire
6.4 score on a scale
Standard Deviation 3.5
7.3 score on a scale
Standard Deviation 4.2

SECONDARY outcome

Timeframe: 2 weeks

The Generalized Anxiety Disorder Scale (GAD-7) is a brief 7-item measure for assessing generalized anxiety disorder. It consists of 7 questions and has a total score range from 0-21 and higher scores indicate greater frequency of anxiety symptoms.

Outcome measures

Outcome measures
Measure
RECLAIM/Intervention
n=8 Participants
Veteran participants randomized to the intervention group. Eight sessions of a brief mindfulness-based intervention that meets weekly in a virtual setting.
Psychoeducation Materials Only/Control Group
n=7 Participants
The investigators will use a psychoeducation-only control group. They will only receive psychoeducational materials (e.g., suggested readings, podcasts, blogs). These are the same materials that the intervention arm participants will receive.
Generalized Anxiety Disorder Scale
10.4 score on a scale
Standard Deviation 5.6
7.6 score on a scale
Standard Deviation 4.4

SECONDARY outcome

Timeframe: 1 Week

The Pain, Enjoyment, and General Activity (PEG) scale is a three-item assessment tool used to monitor chronic pain over time. Each item uses a numerical rating scale from 0 to 10. The scores on each of the 3 items (pain levels on average, pain interference with enjoyment, and pain interference with general activity) are summed and averaged to provide a score that will range from 0-10. Lower scores indicate minimal pain impact.

Outcome measures

Outcome measures
Measure
RECLAIM/Intervention
n=8 Participants
Veteran participants randomized to the intervention group. Eight sessions of a brief mindfulness-based intervention that meets weekly in a virtual setting.
Psychoeducation Materials Only/Control Group
n=7 Participants
The investigators will use a psychoeducation-only control group. They will only receive psychoeducational materials (e.g., suggested readings, podcasts, blogs). These are the same materials that the intervention arm participants will receive.
Pain, Enjoyment, General Activity
4.8 score on a scale
Standard Deviation 3.2
4.5 score on a scale
Standard Deviation 2.2

SECONDARY outcome

Timeframe: 2 months

The Five Facet Mindfulness Questionnaire (FFMQ-15) is a self-report scale that measures an individual's dispositional mindfulness across 5 distinct facets. Responses are made on a 5-point Likert scale, are totaled, and higher scores indicate greater mindfulness. The minimum possible score for each of the mindfulness facets is 3 and the maximum possible score is 15.

Outcome measures

Outcome measures
Measure
RECLAIM/Intervention
n=8 Participants
Veteran participants randomized to the intervention group. Eight sessions of a brief mindfulness-based intervention that meets weekly in a virtual setting.
Psychoeducation Materials Only/Control Group
n=7 Participants
The investigators will use a psychoeducation-only control group. They will only receive psychoeducational materials (e.g., suggested readings, podcasts, blogs). These are the same materials that the intervention arm participants will receive.
Five Facet Mindfulness Questionnaire
Mindfulness Facet: Observing
12 score on a scale
Standard Deviation 2.8
10 score on a scale
Standard Deviation 1.4
Five Facet Mindfulness Questionnaire
Mindfulness Facet: Describing
9.8 score on a scale
Standard Deviation 3.4
10.4 score on a scale
Standard Deviation 1.3
Five Facet Mindfulness Questionnaire
Mindfulness Facet: Awareness
10.8 score on a scale
Standard Deviation 2.9
10 score on a scale
Standard Deviation 1.9
Five Facet Mindfulness Questionnaire
Mindfulness Facet: Non-judging
11.3 score on a scale
Standard Deviation 2.6
11.7 score on a scale
Standard Deviation 2
Five Facet Mindfulness Questionnaire
Mindfulness Facet: Non-reacting
10.1 score on a scale
Standard Deviation 1.7
9.6 score on a scale
Standard Deviation 1.3

Adverse Events

RECLAIM/Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Psychoeducation Materials Only/Control Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Sarah Shue

Richard L. Roudebush VA Medical Center

Phone: 317-988-0278

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place