Elastography and Treatment of Lymphoma

NCT ID: NCT05967975

Last Updated: 2023-08-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

44 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-08-31

Study Completion Date

2025-12-31

Brief Summary

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To determine accuracy of elastography in assessment of superficial lymph nodes response to treatment in cases of lymphoma.

Detailed Description

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Lymphomas are a heterogeneous group of malignancies that arise from the clonal proliferation of lymphocytes. It represents approximately 5% of malignancies. Overall survival is estimated to be 72%. (1)

Lymphomas are broadly classified into Hodgkin lymphoma (HL) (10%) and Non-Hodgkin lymphoma (NHL) (90%).

HL is further classified into classical and non-classical types and NHL into B-cell, T-cell and natural killer (NK) cell types. Diagnosis of lymphoma is confirmed by histopathology (FNAC, True-cut or excisional biopsy).(2) The standard treatment of lymphoma is chemotherapy and radiotherapy.

The modalities used for staging and follow up of lymphoma are:

* Computed Tomography (CT) chest, abdomen and pelvis.
* Positron Emission Tomography (PET/CT).
* Whole body Magnetic Resonance Imaging (MRI).(3)

Sonoelastography is a new technique that depends on the elastic properties of soft tissues, with the idea of malignant lesions being stiffer than benign or normal tissue. It may have a dependable role in evaluation of therapeutic response in patients with lymphoma and can be used for follow up, the same way it has been used in different parts of the body, such as the breast, and thyroid. To the best of our knowledge, there are few studies concerning the role of elastography in the field of lymphoma disease.(4)

Conditions

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Elastography Lymphoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* patients who are histopathologically proven as lymphoma, not receive treatment and have superficial lymphadenopathy.

Exclusion Criteria

* 1-Lymphoma without superficial lymph nodes. 2-patients under treatment.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Kerols Refaat Ayoub

Resident doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kerols Refaat, Resident

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Nagham Nabil, Professor

Role: STUDY_DIRECTOR

Assiut University

Abdel-Monem Sayed, Lecture

Role: STUDY_DIRECTOR

Assiut University

Central Contacts

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Kero Refaat, Resident

Role: CONTACT

+2 01110134427

Other Identifiers

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Elastography and lymphoma

Identifier Type: -

Identifier Source: org_study_id

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