Bizarreness and Anomalous Self Experiences in Schizophrenia

NCT ID: NCT05966610

Last Updated: 2023-07-28

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 12 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-07-12
• Study Completion Date: 2024-09-01

Brief Summary

Several authors suggest that the specific experience felt in clinical encounter, called Praecox Feeling, is directly linked to the psychopathology of Schizophrenia.

However, determining factors of this phenomena, whether cognitive or subjective, remains poorly studied.

Furthermore, Self-Disorders are alterations of the first-person experience regarded as specific of the disease. The investigators plan to study in an exploratory way the phenomenological and subjective links between Praecox Feeling and Self Disorders determinants, while hypothesizing that the clinician's Praecox Feeling can be positively correlated to SDs, as our main objective.

Detailed Description

Several authors suggest that the specific experience felt in clinical encounter, called Praecox Feeling, is directly linked to the psychopathology of Schizophrenia. However, subjective, cognitive or neurophysiologic aspects of this phenomena remains poorly studied.

Furthermore, Self-Disorders (SD) are alterations of the first-person experience and of sense of agency, regarded as specific of Schizophrenia. Unlike Praecox Feeling, clinical, cognitive and neuropsychological determinants of SD are increasingly studied.

The investigators plan to study in an exploratory way the links between Praecox Feeling and SDs determinants, while hypothesizing that the clinician's Praecox Feeling can be positively correlated to SDs, as our main objective.

As a secondary outcome, the investigators will control this correlation by a comparison between SDs evaluation and clinician subjectivity.

The present study also plan to evaluate the associations between Praecox Feeling and clinical features, low and high cognitive level with attentional and social cognition evaluations.

The first step of the research project is to implement this exploratory design in a transversal multicentric setting between centers with a limited number of participants and without follow-up.

Conditions

Schizophrenia

Keywords

Praecox Feeling; Self-Disorders; Subjectivity; Cognition

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• People with a diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) criteria.
• Psychiatric medical situation judged clinically stable : no change of main antipsychotic in treatment in last 15 days.
• People who has given his non-opposition
• Patients affiliated to a social security system

Exclusion Criteria

• Previous meeting of the participant with one of the investigators involved in the clinical assessment and scoring of the study scales.
• Person with a moderate to severe intellectual disability (clinical criteria).
• Person with a neurological pathology with cognitive impact
• Patients with legal protection

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Toulouse

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Tudi GOZE, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Toulouse

Locations

CHU Toulouse

Toulouse, , France

Site Status: RECRUITING

Countries

France

Central Contacts

Tudi GOZE, MD

Role: CONTACT

Phone: 5 61 77 23 60

Email: goze.t@chu-toulouse.fr

Facility Contacts

Tudi GOZE, PH

Role: primary

Other Identifiers

2023-A00049-36

Identifier Type: OTHER

Identifier Source: secondary_id

RC31/22/0517

Identifier Type: -

Identifier Source: org_study_id