Different Administration Routes of Dexmedetomidine on Postoperative Delirium

NCT ID: NCT05952050

Last Updated: 2023-07-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-08-01

Study Completion Date

2023-09-30

Brief Summary

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Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal dexmedetomidine are also effective and convenient. The current study aimed to compare the effect of different administration routes of dexmedetomidine on POD in elderly patients.

Detailed Description

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Conditions

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Dexmedetomidine Postoperative Delirium General Anesthesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Intranasal dexmedetomidine

Group Type EXPERIMENTAL

Dexmedetomidine

Intervention Type DRUG

Different Administration Routes of Dexmedetomidine

Intravenous dexmedetomidine

Group Type ACTIVE_COMPARATOR

Dexmedetomidine

Intervention Type DRUG

Different Administration Routes of Dexmedetomidine

Interventions

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Dexmedetomidine

Different Administration Routes of Dexmedetomidine

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Older than 65 years; General anesthesia for more than two hours;

Exclusion Criteria

\-
Minimum Eligible Age

65 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Zhongshan Hospital Of Traditional Chinese Medicine

OTHER

Sponsor Role collaborator

Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Weitao Chen

Zhongshan, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Weitao Chen

Role: CONTACT

18025661798

Facility Contacts

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Weitao Chen, MD

Role: primary

18025661798

Other Identifiers

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US2023001

Identifier Type: -

Identifier Source: org_study_id

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