Reducing Blood Pressure in Patients With High Cardiovascular Risk
NCT ID: NCT05937685
Last Updated: 2025-05-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
546 participants
INTERVENTIONAL
2023-09-01
2026-07-31
Brief Summary
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The goal of this clinical trial is to test if this team based program is better at helping people reduce their blood pressure than usual care for people with prior heart attack or stroke. The main questions it aims to answer are:
* Do people in the REACH BP program have lower blood pressure at 12 months compared to those getting usual care?
* Do people in the REACH BP program have better Life's Essential 8 scores and patient experience compared to those getting usual care?
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Detailed Description
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BP-REACH aims to test the impact of an intervention on systolic blood pressure (SBP) for individuals with a history of stroke or MI in a randomized controlled trial in the Los Angeles Department of Health Services healthcare system. The primary outcome will be change in systolic blood pressure (SBP) at 12 months.
Hypothesis: Patients randomized to the intervention will achieve \>2.4 mm Hg greater reduction in SBP at 1 year versus those randomized to usual care.
The study population will include participants from the inpatient and outpatient settings in Los Angeles County Department of Health Services health centers. The participants will be randomized in a 1:1 fashion to usual care or intervention, stratified by site, language and cardiovascular event (myocardial infarction, stroke). Outcomes will be collected from all participants at Baseline, 3 month and 12 month timepoints. The primary outcome is SBP.
Participants randomized to the intervention arm will receive additional a home blood pressure monitor, monthly phone calls from a health coach, and medication initiation and titration by a clinical pharmacist. The pharmacist will follow Los Angeles County Department of Health Services expected practices, which align with the ACC/AHA guidelines for blood pressure control and AHA guidelines for Secondary Stroke Prevention.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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Usual Care
Participants receive the usual care received by patients of the medical center
No interventions assigned to this group
Intervention
Participants follow the intervention protocol, including receiving educational materials, a home blood pressure monitor, coaching calls from BP REACH coaches and medication management from a pharmacist.
BP REACH Intervention
Educational materials, written and digital. Home blood pressure monitor and self management education from BP REACH coach. Monthly coaching calls from BP REACH coach. Medication management by pharmacist
Interventions
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BP REACH Intervention
Educational materials, written and digital. Home blood pressure monitor and self management education from BP REACH coach. Monthly coaching calls from BP REACH coach. Medication management by pharmacist
Eligibility Criteria
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Inclusion Criteria
* English or Spanish speaking
* Systolic blood pressure (SBP) ≥ 130 mm Hg
Exclusion Criteria
* SBP \< 130 mm Hg
* Only speaks a language other than English or Spanish
* Cannot provide informed consent due to dementia or aphasia
35 Years
ALL
No
Sponsors
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University of California, Los Angeles
OTHER
University of California, Irvine
OTHER
University of Southern California
OTHER
Responsible Party
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Amytis Towfighi
Principal Investigator
Principal Investigators
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Alejandra Casillas, MD
Role: PRINCIPAL_INVESTIGATOR
University of California, Los Angeles
Amytis Towfighi, MD
Role: PRINCIPAL_INVESTIGATOR
University of Southern California
Locations
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Rancho Los Amigos National Rehabilitation Center
Downey, California, United States
LA General Medical Center
Los Angeles, California, United States
Olive View Medical Center
Sylmar, California, United States
Harbor UCLA Medical Center
Torrance, California, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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