Effects of Antibiotic Prophylaxis on the Healing Parameters Following Surgical Crown Lengthening

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-08-01

Study Completion Date

2024-01-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this clinical trial is to test the effects of prophylactic antibiotics in healthy individuals who are in need of surgical crown lengthening. The main question it aims to answer is if single dose antibiotics prior to surgical crown lengthening has any effects on the healing outcomes.

Participants will be asked to take either

* 2 g of amoxicillin + clavulanate, or
* placebo, one hour prior to surgery and without knowing what medicine they took.

Researchers will compare the wound healing and self-reported outcomes of the antibiotics group and placebo group.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Antibiotic Therapy in Erupted Tooth Extractions

NCT04082598

Tooth Extraction Post-Op Complication Amoxicillin

COMPLETED PHASE4

The Effect of Preoperative Antibiotics on Peri-implant Healing

NCT04280406

Dental Implant Failed

UNKNOWN PHASE1

Adjunctive Antimicrobial Therapy of Periodontitis: Long-Term Effects on Disease Progression and Oral Microbiological Colonization

NCT00707369

Periodontitis

COMPLETED PHASE4

The Effect of Antibiotic Prophylaxis Associated With Dental Implant Surgery

NCT03412305

Infection Control Antibiotic Prophylaxis

COMPLETED PHASE4

Preoperative Dose of Co-amoxiclav for Prevention of Postoperative Complications in Dentoalveolar Surgery

NCT03844776

Infection

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Tooth Diseases Tooth Wear

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

antibiotic prophylaxis

per os 2 g augmentin one hour prior to surgery

Group Type EXPERIMENTAL

Surgical crown lengthening

Intervention Type PROCEDURE

Surgical clinical crown lengthening with bone excision

Augmentin

Intervention Type DRUG

Pre-operative antibiotic prophylaxis (2 g Augmentin)

placebo control

per os placebo one hour prior to surgery

Group Type PLACEBO_COMPARATOR

Surgical crown lengthening

Intervention Type PROCEDURE

Surgical clinical crown lengthening with bone excision

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Surgical crown lengthening

Surgical clinical crown lengthening with bone excision

Intervention Type PROCEDURE

Augmentin

Pre-operative antibiotic prophylaxis (2 g Augmentin)

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* in need of surgical crown lengthening operation in one/two teeth

Exclusion Criteria

* systemic diseases which may affect periodontal tissues and/or healing process such as diabetes mellitus
* antibiotic or anti-inflammatory drug use in the last 3 months
* pregnancy/lactation
* chronic steroid, immunosuppressant or NSAD use
* age \<18 years
* positive bleeding on probing at the surgical site and/or active periodontal disease
* \<2 mm keratinized mucosa at the surgical site following surgery (estimated surgical outcome before the operation)
* Miller 2 or 3 tooth mobility
* penicillin allergy
* unwilling to participate

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes