Stimulant Use and Methylation in HIV

NCT ID: NCT05916989

Last Updated: 2023-11-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

53 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-09-30

Study Completion Date

2022-10-26

Brief Summary

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This study will leverage extracted leukocyte DNA specimens from a completed NIH-funded project to examine the efficacy of a behavioral intervention model that reduced stimulant use on DNA methylation over 6 months.

Detailed Description

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Conditions

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HIV Infections Methamphetamine-dependence Methamphetamine Abuse

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Leukocyte DNA Samples

Leukocyte DNA specimens extracted from participants enrolled in a completed NIH funded trial will be examined to determine if prior exposure to different behavioral interventions modifies DNA methylation patterns over 6 months.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* At least 18 years old
* Documentation of HIV-positive serostatus
* Speak English
* Biological verification of recent methamphetamine use
* Completion of at least three contingency management (CM) visits
* Self reported anal sex with a man in the past 12 months

Exclusion Criteria

* Inability to provide informed consent, evidenced by cognitive impairment
* HIV negative serostatus
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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New York University

OTHER

Sponsor Role collaborator

Northwestern University

OTHER

Sponsor Role collaborator

University of California, San Francisco

OTHER

Sponsor Role collaborator

National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

Florida International University

OTHER

Sponsor Role lead

Responsible Party

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Adam Carrico, PhD

Professor and Chair

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Adam W Carrico, PhD

Role: PRINCIPAL_INVESTIGATOR

Florida International University

Locations

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Florida International University

Miami, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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R01DA033854

Identifier Type: NIH

Identifier Source: secondary_id

View Link

20180865

Identifier Type: -

Identifier Source: org_study_id

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