Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry

NCT ID: NCT05915078

Last Updated: 2024-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-15

Study Completion Date

2027-06-30

Brief Summary

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This prospective, single-arm, multicenter registry is being conducted to collect real world post-market data from patients aged from 6 months to 17 years of age who are undergoing an in-office ear tube placement procedure (tympanostomy) using the Tula® System. The Registry will include up to 20 centers in the US and up to 200 patients for the initial evaluation.

The FDA-approved Tula System includes the Tula Iontophoresis System (IPS) with TYMBION™ otic anesthetic for local anesthesia of the ear drum and the Tula Tube Delivery System (TDS) for ear tube placement. Clinical research established the safety, efficacy and tolerability of this system for in-office procedures in the pediatric population. Patients will be treated and evaluated according to standard medical care. Outcome data is collected up to 6 months following extrusion or removal of their tube(s).

Detailed Description

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Conditions

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Otitis Media With Effusion Acute Otitis Media Otitis Media

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Tula Tympanostomy

Patients undergoing in-office tympanostomy using the Tula® System

Iontophoresis and tube placement

Intervention Type COMBINATION_PRODUCT

Iontophoretic delivery of TYMBION™ otic anesthetic using the Tula Iontophoresis System and tube insertion using the Tula Tube Delivery System

Interventions

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Iontophoresis and tube placement

Iontophoretic delivery of TYMBION™ otic anesthetic using the Tula Iontophoresis System and tube insertion using the Tula Tube Delivery System

Intervention Type COMBINATION_PRODUCT

Eligibility Criteria

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Inclusion Criteria

* Patients ages 6 months through 17 years of age (inclusive) at time of tympanostomy in-office using the Tula® System
* Patients who are candidates for in-office tube placement using the Tula System according to the System Instructions For Use

Exclusion Criteria

* Patients who are wards are not included
Minimum Eligible Age

6 Months

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Smith & Nephew, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Advanced ENT and Allergy

Louisville, Kentucky, United States

Site Status RECRUITING

Regional Otolaryngology Head and Neck Associates

Cherry Hill, New Jersey, United States

Site Status RECRUITING

Rutgers Robert Wood Johnson Medical School

New Brunswick, New Jersey, United States

Site Status RECRUITING

Columbia University Vagelos College of Physicians and Surgeons

New York, New York, United States

Site Status RECRUITING

Ogden Clinic - Professional Center North

Ogden, Utah, United States

Site Status RECRUITING

Peak Pediatric Ear, Nose and Throat

Provo, Utah, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Catherine E Whittall, BsC, Ph.D

Role: CONTACT

+44 7841 868997

Facility Contacts

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Jennifer Leonard

Role: primary

502-893-0159 ext. 1185

Megan Morgan

Role: primary

Kelvin M Kwong

Role: primary

Ashley Erickson

Role: primary

Jordan C Schramm

Role: primary

Other Identifiers

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Tula Registry

Identifier Type: -

Identifier Source: org_study_id

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