Multiparametric Echocardiography and Cardiac Biomarkers in Pediatric Inflammatory Heart Diseases

NCT ID: NCT05911386

Last Updated: 2023-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-30

Study Completion Date

2023-09-30

Brief Summary

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Acquired inflammatory or infectious cardiac diseases, in pediatrics, include Kawasaki disease, myocarditis, and Covid-19-related Pediatric Multisystemic Inflammatory Syndrome (PIMS).

These 3 inflammatory cardiac diseases have clinical, biological, and echographic similarities and differences. Nevertheless their modalities of monitoring, management and evolution are different. The investigators wish to retrospectively analyze biological and echocardiographic data of Kawasaki disease, myocarditis, PIMS patients managed at Nancy Children Hospital from January 1, 2017 to June 31, 2023.

The primary objective of this study is to identify, for these 3 pathologies, the prognostic factors of initiation of inotropic support.

The secondary objective is to identify the prognostic factors of degradation of ventricular function.

Detailed Description

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Conditions

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Myocarditis Pediatric Inflammatory Multisystem Syndrome Kawasaki Disease

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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MYOCARDITIS

No intervention Study of available clinical, biological, and echocardiographic data

study of biological samples and echocardiographic data and link with need of hemodynamic support

Intervention Type OTHER

observational study : there is no intervention

KAWASAKI

No intervention Study of available clinical, biological, and echocardiographic data

study of biological samples and echocardiographic data and link with need of hemodynamic support

Intervention Type OTHER

observational study : there is no intervention

PIMS

No intervention Study of available clinical, biological, and echocardiographic data

study of biological samples and echocardiographic data and link with need of hemodynamic support

Intervention Type OTHER

observational study : there is no intervention

Interventions

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study of biological samples and echocardiographic data and link with need of hemodynamic support

observational study : there is no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* diagnostic of PIMS, myocarditis or kawasaki disease patients
* age \< 18 years

Exclusion Criteria

* uncertain diagnosis
* other complex heart disease
* management out of Nancy University children hospital center
Minimum Eligible Age

0 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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BOSSER Gilles

chief of congenital and pediatric cardiology department

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Gilles BOSSER

Vandœuvre-lès-Nancy, , France

Site Status

Countries

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France

Central Contacts

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Aurelien Capogna

Role: CONTACT

+33603566308

Facility Contacts

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Gilles BOSSER, PhD

Role: primary

Other Identifiers

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2023PI058

Identifier Type: -

Identifier Source: org_study_id

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