Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
20 participants
INTERVENTIONAL
2023-10-01
2027-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Canagliflozin and Gemcitabine
Canagliflozin and Gemcitabine
on the first, 8th and 15th day of treatment, patients were given intravenous drip of 1000mg/m2 gemcitabine, and 21 days was a course of treatment, lasting for 6 courses.
Take 400mg canagliflozin orally every day, and continue to use it until the end of chemotherapy. According to the patient's tolerance to disulfiram, the dose of canagliflozin can be re-evaluated during the treatment, and the highest dose is 125mg per day. The clinical symptoms, signs and adverse reactions of patients were observed, and the treatment effect of patients was evaluated after two consecutive cycles with 4 weeks as a cycle
standard cisplatin
Gemcitabine
on the first, 8th and 15th day of treatment, patients were given 1000mg/m2 gemcitabine intravenously, and 21 days was a course of treatment, lasting for 6 courses.
Interventions
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Canagliflozin and Gemcitabine
on the first, 8th and 15th day of treatment, patients were given intravenous drip of 1000mg/m2 gemcitabine, and 21 days was a course of treatment, lasting for 6 courses.
Take 400mg canagliflozin orally every day, and continue to use it until the end of chemotherapy. According to the patient's tolerance to disulfiram, the dose of canagliflozin can be re-evaluated during the treatment, and the highest dose is 125mg per day. The clinical symptoms, signs and adverse reactions of patients were observed, and the treatment effect of patients was evaluated after two consecutive cycles with 4 weeks as a cycle
Gemcitabine
on the first, 8th and 15th day of treatment, patients were given 1000mg/m2 gemcitabine intravenously, and 21 days was a course of treatment, lasting for 6 courses.
Eligibility Criteria
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Exclusion Criteria
18 Years
ALL
No
Sponsors
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College of Pharmaceutical Sciences at Zhejiang University
UNKNOWN
The Innovation Institute for Artificial Intelligence in Medicine, Zhejiang University
UNKNOWN
Zhang Xiaofeng,MD
OTHER
Responsible Party
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Zhang Xiaofeng,MD
chief physician
Locations
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Hangzhou first people's Hospital
Hangzhou, Zhejiang, China
Countries
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Central Contacts
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Xiaofeng Zhang
Role: CONTACT
Other Identifiers
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20230519
Identifier Type: -
Identifier Source: org_study_id
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