AQUACEL® Ag+ Extra™ and Cutimed™ Sorbact® Dressing in the Management of Venous Leg Ulcers Over a 12-week Period

NCT ID: NCT05892341

Last Updated: 2025-12-02

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

203 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-12-05

Study Completion Date

2024-02-14

Brief Summary

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Study is to provide evidence comparing AQUACEL® Ag+ Extra™ versus Cutimed® Sorbact® in the progression of wounds towards healing

Detailed Description

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Post market, multi-centre, randomised, open label, multi-national, prospective study to provide evidence comparing AQUACEL® Ag+ Extra™ versus Cutimed® Sorbact® in the progression of wounds towards healing

Conditions

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Venous Leg Ulcer Diabetic Foot

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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AQUACEL® Ag+ Extra™

AQUACEL® Ag+ Extra™ is approved, needle-bonded nonwoven fabric layered and stitch-bonded wound dressing

Group Type ACTIVE_COMPARATOR

AQUACEL® Ag+ Extra™

Intervention Type DEVICE

Wound treatment with AQUACEL® Ag+ Extra™ dressing

Cutimed® Sorbact®

Cutimed® Sorbact® is approved, bacterial and fungi binding wound dressing

Group Type ACTIVE_COMPARATOR

Cutimed® Sorbact®

Intervention Type DEVICE

Wound treatment with Cutimed® Sorbact® dressing

Interventions

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AQUACEL® Ag+ Extra™

Wound treatment with AQUACEL® Ag+ Extra™ dressing

Intervention Type DEVICE

Cutimed® Sorbact®

Wound treatment with Cutimed® Sorbact® dressing

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Venous insufficiency as defined by CEAP Classification of C6
* One wound amendable to treatment with either AQUACEL® Ag+ Extra™ or Cutimed® Sorbact®
* Wounds that have been present for at least 2 months
* Reliable and available for follow-up
* 18 years or older
* Able and willing to provide informed consent
* Able to tolerate compression therapy for Venus Leg Ulcer
* Must be able to be compliant with compression therapy

Exclusion Criteria

* Known sensitivities or allergies to components of the AQUACEL® Ag+ Extra™ or Cutimed® Sorbact®
* Continued use of petroleum gel/ creams/ oil-based products
* Active treatment for cancer or completed within the last 3 months
* Documented severe malnutrition
* Malignant wounds
* Systemic infection actively treated with antibiotics
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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NAMSA

OTHER

Sponsor Role collaborator

ConvaTec Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Catarina Saavedra, MD

Role: PRINCIPAL_INVESTIGATOR

Convatec Colombia Clinic

Locations

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Convatec Colombia Clinic

Barranquilla, , Colombia

Site Status

Convatec Colombia Clinic

Bogotá, , Colombia

Site Status

Convatec Colombia Clinic

Bucaramanga, , Colombia

Site Status

Convatec Colombia Clinic

Cali, , Colombia

Site Status

Convatec Colombia Clinic

Cartagena, , Colombia

Site Status

Convatec Colombia Clinic

Medellín, , Colombia

Site Status

Germany

Augsburg, , Germany

Site Status

Germany

Berlin, , Germany

Site Status

Germany

Bochum, , Germany

Site Status

Germany

Düsseldorf, , Germany

Site Status

Germany

Holzkirchen, , Germany

Site Status

Germany

Ingolstadt, , Germany

Site Status

Germany Clinic II

München, , Germany

Site Status

Germany Clinic I

München, , Germany

Site Status

Germany

Nuremberg, , Germany

Site Status

Germany

Ratzeburg, , Germany

Site Status

Germany

Rosenheim, , Germany

Site Status

VCTC UK

Derby, , United Kingdom

Site Status

Countries

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Colombia Germany United Kingdom

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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WC-22-435

Identifier Type: -

Identifier Source: org_study_id

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