Effect of Systematic Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery
NCT ID: NCT05887765
Last Updated: 2025-09-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE4
90 participants
INTERVENTIONAL
2023-10-17
2025-07-29
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
The Effect of Botulinum Toxin A Injections on Ankle Dorsiflexion Following Internal Fixation of Tibial Pilon Fractures
NCT02051933
Dynamic Splinting for Plantarflexion in Spastic Hemiplegia
NCT01329705
Impact of an Orthotic Intervention in Children With Peripheral Neuropathy
NCT03655587
Management of Pes Planovalgus With Talocalcaneal Coalition ,Osteotomy vs Arthroereisis
NCT05170698
Physiological and Functional Effects of Percutaneous Neuromodulation vs Transcutaneous Neuromodulation
NCT06365931
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
After ankle or foot surgery, children need good analgesia. Peripheral nerve blocks have provided a safe, effective method to control early postoperative pain when symptoms are most severe.
The safety of local anesthesia is particularly important in children due to the much lower toxicity threshold of local anesthetics. The use of an effective adjuvant, such as Dexamethasone, could allow for the use of a higher dilution of local anesthetics while maintaining and enhancing their analgesic effect.
There is multiple research where intravenous and perineural dexamethasone use has been compared in adults. However, there is a huge lack of research regarding children.
In this study, investigators compare different doses of systemic dexamethasone. Before the anesthesia, the patients receive dexamethasone intravenously. Groups 2 and 3 have dexamethasone doses of 0.1mg/kg, and 0.2mg/kg.
The investigator's goal is to find a dexamethasone dose that is as low as possible but at the same time covers the need for good pain relief and fast recovery postoperatively.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
placebo injection
5ml of 0,9% sodium chloride - before the popliteal nerve block
Sodium Chloride 0.9% Inj
administration of 5ml 0,9% sodium chloride - 30 minutes before the popliteal nerve block
0,1mg/kg Dexamethasone
0,1mg/kg dexamethasone sodium phosphate - before the popliteal nerve block
0,1mg/kg Dexamethasone
administration of 0,1mg/kg Dexamethasone - 30 minutes before the popliteal nerve block
0,2mg/kg Dexamethasone
0,2mg/kg dexamethasone sodium phosphate - before the popliteal nerve block
0,2mg/kg Dexamethasone
administration of 0,2mg/kg Dexamethasone - 30 minutes before the popliteal nerve block
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Sodium Chloride 0.9% Inj
administration of 5ml 0,9% sodium chloride - 30 minutes before the popliteal nerve block
0,1mg/kg Dexamethasone
administration of 0,1mg/kg Dexamethasone - 30 minutes before the popliteal nerve block
0,2mg/kg Dexamethasone
administration of 0,2mg/kg Dexamethasone - 30 minutes before the popliteal nerve block
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* body weight \> 5kg
Exclusion Criteria
* coagulation disorders
* immunodeficiency
* ASA= or \>4
* steroid medication in regular use
3 Months
18 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Poznan University of Medical Sciences
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Tomasz Kotwicki, Prof.dr hab.
Role: STUDY_CHAIR
Poznań University of Medical Sciences
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Department of Spine Diseases and Pediatric Orthopedics, University of Medical Sciences, Poznań, Poland
Poznan, Wielkopolska, Poland
Poznan Univesity of Medical Sciences
Poznan, Wielkopolska, Poland
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
8/2023
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.