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Changes of Optical Quality During the Peak of the Covid-19 Pandemic

NCT ID: NCT05882383

Last Updated: 2023-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

110 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-11-25

Study Completion Date

2023-01-20

Brief Summary

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To explore whether cornea structure, and optical quality are affected by the covid-19 infection.

Detailed Description

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Participants with healthy corneas admitted to Tianjin Eye Hospital from November 25 to January 20, 2022 were followed up . At the end of the follow-up, the investigators recorded in detail whether the patients had undergone real-time reverse transcriptase polymerase chain reaction (covid-19 RT-PCR tests) testing, testing time and results. The presence of PCR-positive during follow-up is considered to be covid-19 infection; PCR-Negative and no symptoms of infection during the follow-up period are considered not infected; participants with symptoms but no PCR test were excluded from the study.Participants were divided into three groups according to the RT-PCR results and the presence or absence of symptoms of infection during follow-up. pentacam (Pentacam HR, Oculus, Wetzlar, Germany) was performed during follow-up and the results were recorded,and the data was statistically managed and compared.

Conditions

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Corneal Wavefront Aberration SARS-CoV-2

Keywords

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optical quality

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Control Group

unifected with SARS-CoV-2 during follow-up

No interventions assigned to this group

Group A

uninfected at the first visit, have been infected at the second visit

No interventions assigned to this group

group B

have been infected at twice visit

No interventions assigned to this group

Eligibility Criteria

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Exclusion Criteria

1. corneal disease;
2. ocular trauma;
3. Pregnant and lactating women;
Minimum Eligible Age

18 Years

Maximum Eligible Age

32 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Tianjin Eye Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yan Wang, Prof

Role: STUDY_CHAIR

Tianjin eye hosipital

Locations

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Tianjin Eye Hospital

Tianjin, Tianjin Municipality, China

Site Status

Countries

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China

Other Identifiers

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KY-2023019

Identifier Type: -

Identifier Source: org_study_id