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Gender Heterogeneity in the Influencing Factors for Cerebral Microbleeds in Acute Ischemic Stroke Patients

NCT ID: NCT05882123

Last Updated: 2023-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

482 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2015-12-31

Brief Summary

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The investigators continuously collected data from 482 AIS inpatients at the Neurology Department of Hebei General Hospital. Both demographic and clinical data were collected from the study subjects. Different head magnetic resonance imaging sequences were used to assess the subjects' CMBs, white matter lesions, and old lacunar infarcts (LI). Various statistical methods, including the t-test, χ2 test, and logistic regression, were used to analyze the gender heterogeneity of the influencing factors for CMBs in AIS patients.

Detailed Description

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Conditions

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Acute Ischemic Stroke

Keywords

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Acute ischemic stroke Cerebral microbleeds Influencing factors Gender heterogeneity

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Comparison of clinical data between AIS patients in CMB and non-CMB groups

No interventions assigned to this group

without CMBs; with CMBs

cerebral microbleeds

Intervention Type OTHER

Whether patients with acute ischemic stroke are complicated by cerebral microbleeds

male; female

cerebral microbleeds

Intervention Type OTHER

Whether patients with acute ischemic stroke are complicated by cerebral microbleeds

Interventions

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cerebral microbleeds

Whether patients with acute ischemic stroke are complicated by cerebral microbleeds

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Aged 18 years and older
* Must meet the diagnostic criteria for AIS as presented in the Chinese Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke 2014
* Must be in good physical condition and have the ability to cooperate with MRI examinations
* Must have underwent SWI

Exclusion Criteria

* MRI contraindications present, such as cardiac pacemaker, cardiac stents, or metal implants
* Head MRI or carotid artery ultrasound suggests the presence of severe stenosis or occlusion in the intracranial or extracranial segments of the cerebral arteries
* Severe comorbid diseases, such as cardiac, pulmonary, hepatic, and renal insufficiencies
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Xin Guo

OTHER

Sponsor Role lead

Responsible Party

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Xin Guo

Attending physician

Responsibility Role SPONSOR_INVESTIGATOR

References

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Guo X, Xing Y, Teng Z, Shen Z, Guo X, Lv P, Tian S. Gender heterogeneity in the influencing factors for cerebral microbleeds in acute ischemic stroke patients. Curr Med Res Opin. 2023 Jul;39(7):1045-1054. doi: 10.1080/03007995.2023.2219581. Epub 2023 Jun 20.

Reference Type DERIVED
PMID: 37259500 (View on PubMed)

Other Identifiers

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20220642

Identifier Type: -

Identifier Source: org_study_id