R&D Study to Evaluate Cordio's Usability and to Collect Patient Speech Utterances

NCT ID: NCT05876533

Last Updated: 2024-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

216 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-18

Study Completion Date

2025-03-15

Brief Summary

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To determine the usability and technical aspects of Cordio HearO™

Detailed Description

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The system (including App and server) will be tested under simulated use conditions with representative users to identify potential changes required to the application user interface, to improve user performance and satisfaction, and to inform future design options.

The recordings data will also be used for algorithm improvement

Conditions

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Chronic Heart Failure

Keywords

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CHF

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Cordio HearO

Cordio HearO is a software medical device that remotely monitors Congestive Heart Failure (CHF) patients by detecting changes in the patients' recorded voice relative to a baseline. The system is comprised of a mobile application (or "app") that is deployed on a mobile platform, and a web-based portal that enables caregivers to manage their patients

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Adults patients
2. Diagnosed with Symptomatic Chronic Heart Failure \[NYHA II-IVa (ambulatory)\]
3. At least one of the following:

1. One ADHF hospitalization in the last 12 months
2. One unplanned IV/SC diuretic administration in the last 6 months
3. Two unplanned IV/SC diuretic administration in the last 12 months
4. NTProBNP \>500 pg/ml or BNP\*\> 150 pg/ml at screening visit
4. Clinically stable HF
5. Willing to participate as evidenced by signing the written informed consent.
6. Male or non-pregnant female patient (pre-menopausal women will confirm verbally).

Exclusion Criteria

1. Not able to read in Hebrew, Russian, Arabic, English and/or Spanish.
2. Unable to comply with daily use of the App
3. Major cardiovascular event
4. Had a Cardiac Resynchronization Device (CRT) implanted or upgrading ≤ 1 month prior to screening visit.
5. Has estimated Glomerular Filtration Rate (eGFR) \< 30 ml/min/1.73 meter square (Cockroft-Gault formula).
6. Is likely to undergo heart transplantation/ LVAD within 6 months of Screening Visit.
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cordio Medical

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ronit Haviv, PhD

Role: STUDY_DIRECTOR

Cordio Medical

Locations

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Kurker Family Medicine

South Windsor, Connecticut, United States

Site Status

C&R Research Services

Cape Coral, Florida, United States

Site Status

C&R Research Services

Miami, Florida, United States

Site Status

C&R Research Services

Miami, Florida, United States

Site Status

Lake County Med Grp

Athens, Georgia, United States

Site Status

Barzilai Medical Center- Cardiology

Ashkelon, , Israel

Site Status

Heart Failure Clinic - Clallit Be'er Sheva

Beersheba, , Israel

Site Status

Rabin Medical Center - Cardiology- CHF

Petah Tikva, , Israel

Site Status

Countries

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United States Israel

Other Identifiers

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CLN0016

Identifier Type: -

Identifier Source: org_study_id