Trial Outcomes & Findings for Effects of Tobacco Flavoring and Liquid Composition on Vaping Topography (NCT NCT05876091)
NCT ID: NCT05876091
Last Updated: 2025-12-22
Results Overview
Measure of vaping topography counting total number of puffs.
Recruitment status
TERMINATED
Study phase
NA
Target enrollment
21 participants
Primary outcome timeframe
Single Session, Approximately 2 hours in duration
Results posted on
2025-12-22
Participant Flow
Participant milestones
| Measure |
Overall Study Population
SESSION 1: Participants puff their own brand liquid on study.
SESSIONS 2-5: Participants puff 1 of 4 randomly assigned tobacco flavor formulations at each visit on study.
SESSIONS 6-7: Participants puff 1 of 2 randomly assigned nicotine formulations at each visit on study.
|
|---|---|
|
Session 1: Own Brand Topography
STARTED
|
18
|
|
Session 1: Own Brand Topography
Own Brand Directed Vaping
|
18
|
|
Session 1: Own Brand Topography
Own Brand Ad Lib Vaping
|
18
|
|
Session 1: Own Brand Topography
COMPLETED
|
18
|
|
Session 1: Own Brand Topography
NOT COMPLETED
|
0
|
|
Sessions 2-5: Tobacco Flavors
STARTED
|
18
|
|
Sessions 2-5: Tobacco Flavors
Cowboy Liquid Ad Lib
|
17
|
|
Sessions 2-5: Tobacco Flavors
Cowboy Liquid Directed
|
17
|
|
Sessions 2-5: Tobacco Flavors
RY4 Liquid Ad Lib
|
17
|
|
Sessions 2-5: Tobacco Flavors
RY4 Liquid Directed
|
17
|
|
Sessions 2-5: Tobacco Flavors
Red Oak Liquid Ad Lib
|
17
|
|
Sessions 2-5: Tobacco Flavors
Red Oak Liquid Directed
|
17
|
|
Sessions 2-5: Tobacco Flavors
Unflavored Liquid Ad Lib
|
17
|
|
Sessions 2-5: Tobacco Flavors
Unflavored Liquid Directed
|
17
|
|
Sessions 2-5: Tobacco Flavors
COMPLETED
|
17
|
|
Sessions 2-5: Tobacco Flavors
NOT COMPLETED
|
1
|
|
Sessions 6-7: Nicotine Formulations
STARTED
|
17
|
|
Sessions 6-7: Nicotine Formulations
Synthetic Liquid Ad Lib
|
17
|
|
Sessions 6-7: Nicotine Formulations
Synthetic Liquid Directed
|
17
|
|
Sessions 6-7: Nicotine Formulations
Tobacco Derived Liquid Ad Lib
|
17
|
|
Sessions 6-7: Nicotine Formulations
Tobacco Derived Liquid Directed
|
17
|
|
Sessions 6-7: Nicotine Formulations
COMPLETED
|
17
|
|
Sessions 6-7: Nicotine Formulations
NOT COMPLETED
|
0
|
Reasons for withdrawal
| Measure |
Overall Study Population
SESSION 1: Participants puff their own brand liquid on study.
SESSIONS 2-5: Participants puff 1 of 4 randomly assigned tobacco flavor formulations at each visit on study.
SESSIONS 6-7: Participants puff 1 of 2 randomly assigned nicotine formulations at each visit on study.
|
|---|---|
|
Sessions 2-5: Tobacco Flavors
Lost to Follow-up
|
1
|
Baseline Characteristics
Effects of Tobacco Flavoring and Liquid Composition on Vaping Topography
Baseline characteristics by cohort
| Measure |
Vaping -
n=18 Participants
Description The order of directed and ad libitum bouts are randomized within participants at each session.
SESSION 1: Participants puff their own brand liquid on study.
SESSIONS 2-5: Participants puff 1 of 4 randomly assigned tobacco flavor formulations at each visit on study.
SESSIONS 6-7: Participants puff 1 of 2 randomly assigned nicotine formulations at each visit on study.
Participants also undergo collection of saliva samples and optionally undergo collection of oral cell and oral rinse samples throughout study.
Vaping: Undergo vape puffing regimen
Biospecimen Collection: Undergo collection of saliva samples and oral cell samples
Questionnaire Administration: Administer Quesitonnaire
|
|---|---|
|
Age, Continuous
|
35.8 years
STANDARD_DEVIATION 10.76 • n=18 Participants
|
|
Sex: Female, Male
Female
|
11 Participants
n=18 Participants
|
|
Sex: Female, Male
Male
|
7 Participants
n=18 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
1 Participants
n=18 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
17 Participants
n=18 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=18 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=18 Participants
|
|
Race (NIH/OMB)
Asian
|
3 Participants
n=18 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=18 Participants
|
|
Race (NIH/OMB)
Black or African American
|
5 Participants
n=18 Participants
|
|
Race (NIH/OMB)
White
|
7 Participants
n=18 Participants
|
|
Race (NIH/OMB)
More than one race
|
1 Participants
n=18 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
2 Participants
n=18 Participants
|
|
Region of Enrollment
United States
|
18 participants
n=18 Participants
|
PRIMARY outcome
Timeframe: Single Session, Approximately 2 hours in durationMeasure of vaping topography counting total number of puffs.
Outcome measures
| Measure |
Sessions 2-5: Unflavored Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Unflavored vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Red Oak vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Red Oak vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Directed
n=17 Participants
Mean directed ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Tobacco Derived vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Tobacco Derived vaping liquid
|
Session 1: Own Brand Puff Duration Ad Lib
n=18 Participants
Mean ad lib puff duration: Own Brand
|
Session 1: Own Brand Puff Duration Directed
n=18 Participants
Mean directed puff duration: Own Brand
|
Sessions 2-5: Cowboy Vaping Liquid Puff Duration Ad Lib
n=17 Participants
Mean ad lib puff duration: Cowboy vaping liquid
|
Sessions 2-5: Cowboy Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Cowboy vaping liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: RY4 Double Vaping Liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: RY4 Double vaping liquid
|
Sessions 2-5: Unflavored Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Unflavored vaping liquid
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Puff Topography: Puff Count
|
5.8 Number of Puffs
Standard Error 0.9
|
13.0 Number of Puffs
Standard Error 2.2
|
6.3 Number of Puffs
Standard Error 1.2
|
14.3 Number of Puffs
Standard Error 2.4
|
7.1 Number of Puffs
Standard Error 0.9
|
13.4 Number of Puffs
Standard Error 1.8
|
7.0 Number of Puffs
Standard Error 0.9
|
13.9 Number of Puffs
Standard Error 2.3
|
6.4 Number of Puffs
Standard Error 0.8
|
13.2 Number of Puffs
Standard Error 2.2
|
5.8 Number of Puffs
Standard Error 0.8
|
15.4 Number of Puffs
Standard Error 3.1
|
5.9 Number of Puffs
Standard Error 0.9
|
13.2 Number of Puffs
Standard Error 2.2
|
PRIMARY outcome
Timeframe: Single Session, Approximately 2 hours in durationMeasure of vaping topography counting duration of puffs in seconds.
Outcome measures
| Measure |
Sessions 2-5: Unflavored Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Unflavored vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Red Oak vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Red Oak vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Directed
n=17 Participants
Mean directed ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Tobacco Derived vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Tobacco Derived vaping liquid
|
Session 1: Own Brand Puff Duration Ad Lib
n=18 Participants
Mean ad lib puff duration: Own Brand
|
Session 1: Own Brand Puff Duration Directed
n=18 Participants
Mean directed puff duration: Own Brand
|
Sessions 2-5: Cowboy Vaping Liquid Puff Duration Ad Lib
n=17 Participants
Mean ad lib puff duration: Cowboy vaping liquid
|
Sessions 2-5: Cowboy Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Cowboy vaping liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: RY4 Double Vaping Liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: RY4 Double vaping liquid
|
Sessions 2-5: Unflavored Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Unflavored vaping liquid
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Puff Topography: Puff Duration (in Seconds)
|
3.2 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
2.1 Mean Duration of Puffs (in seconds)
Standard Error 0.2
|
2.9 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
2.4 Mean Duration of Puffs (in seconds)
Standard Error 0.4
|
3.0 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
2.2 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
2.9 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
2.2 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
3.5 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
2.3 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
3.1 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
2.5 Mean Duration of Puffs (in seconds)
Standard Error 0.4
|
3.0 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
2.3 Mean Duration of Puffs (in seconds)
Standard Error 0.3
|
PRIMARY outcome
Timeframe: Single Session, Approximately 2 hours in durationMeasure of vaping topography counting the interval between puffs in seconds.
Outcome measures
| Measure |
Sessions 2-5: Unflavored Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Unflavored vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Red Oak vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Red Oak vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Directed
n=17 Participants
Mean directed ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Tobacco Derived vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Tobacco Derived vaping liquid
|
Session 1: Own Brand Puff Duration Ad Lib
n=18 Participants
Mean ad lib puff duration: Own Brand
|
Session 1: Own Brand Puff Duration Directed
n=18 Participants
Mean directed puff duration: Own Brand
|
Sessions 2-5: Cowboy Vaping Liquid Puff Duration Ad Lib
n=17 Participants
Mean ad lib puff duration: Cowboy vaping liquid
|
Sessions 2-5: Cowboy Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Cowboy vaping liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: RY4 Double Vaping Liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: RY4 Double vaping liquid
|
Sessions 2-5: Unflavored Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Unflavored vaping liquid
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Puff Topography: Inter Puff Interval (IPI)
|
56.7 Mean number of seconds between puffs
Standard Error 4.0
|
55.1 Mean number of seconds between puffs
Standard Error 8.1
|
60.6 Mean number of seconds between puffs
Standard Error 5.4
|
84.6 Mean number of seconds between puffs
Standard Error 12.0
|
59.3 Mean number of seconds between puffs
Standard Error 4.1
|
78.7 Mean number of seconds between puffs
Standard Error 11.0
|
56.6 Mean number of seconds between puffs
Standard Error 3.5
|
82.2 Mean number of seconds between puffs
Standard Error 14.0
|
55.2 Mean number of seconds between puffs
Standard Error 6.1
|
61.4 Mean number of seconds between puffs
Standard Error 10.7
|
58.0 Mean number of seconds between puffs
Standard Error 4.2
|
71.6 Mean number of seconds between puffs
Standard Error 10.3
|
54.2 Mean number of seconds between puffs
Standard Error 3.6
|
71.6 Mean number of seconds between puffs
Standard Error 8.7
|
PRIMARY outcome
Timeframe: Single Session, Approximately 2 hours in durationMeasure of vaping topography measuring the volume per puff in ml.
Outcome measures
| Measure |
Sessions 2-5: Unflavored Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Unflavored vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Red Oak vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Red Oak vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Directed
n=17 Participants
Mean directed ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Tobacco Derived vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Tobacco Derived vaping liquid
|
Session 1: Own Brand Puff Duration Ad Lib
n=18 Participants
Mean ad lib puff duration: Own Brand
|
Session 1: Own Brand Puff Duration Directed
n=18 Participants
Mean directed puff duration: Own Brand
|
Sessions 2-5: Cowboy Vaping Liquid Puff Duration Ad Lib
n=17 Participants
Mean ad lib puff duration: Cowboy vaping liquid
|
Sessions 2-5: Cowboy Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Cowboy vaping liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: RY4 Double Vaping Liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: RY4 Double vaping liquid
|
Sessions 2-5: Unflavored Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Unflavored vaping liquid
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Puff Topography: Puff Volume
|
88.3 Volume per puff (ml)
Standard Error 13.5
|
57.5 Volume per puff (ml)
Standard Error 6.5
|
74.9 Volume per puff (ml)
Standard Error 10.61
|
86.7 Volume per puff (ml)
Standard Error 14.9
|
96.3 Volume per puff (ml)
Standard Error 13.5
|
76.9 Volume per puff (ml)
Standard Error 9.8
|
92.0 Volume per puff (ml)
Standard Error 15.2
|
63.5 Volume per puff (ml)
Standard Error 13.2
|
102.2 Volume per puff (ml)
Standard Error 16.1
|
66.2 Volume per puff (ml)
Standard Error 11.4
|
81.4 Volume per puff (ml)
Standard Error 14.7
|
83.6 Volume per puff (ml)
Standard Error 17.2
|
103.1 Volume per puff (ml)
Standard Error 18.6
|
63.9 Volume per puff (ml)
Standard Error 8.1
|
PRIMARY outcome
Timeframe: Single Session, Approximately 2 hours in durationMeasure of vaping topography measuring the rate of flow per puff in milliliters per second.
Outcome measures
| Measure |
Sessions 2-5: Unflavored Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Unflavored vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Red Oak vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Red Oak vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Directed
n=17 Participants
Mean directed ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Tobacco Derived vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Tobacco Derived vaping liquid
|
Session 1: Own Brand Puff Duration Ad Lib
n=18 Participants
Mean ad lib puff duration: Own Brand
|
Session 1: Own Brand Puff Duration Directed
n=18 Participants
Mean directed puff duration: Own Brand
|
Sessions 2-5: Cowboy Vaping Liquid Puff Duration Ad Lib
n=17 Participants
Mean ad lib puff duration: Cowboy vaping liquid
|
Sessions 2-5: Cowboy Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Cowboy vaping liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: RY4 Double Vaping Liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: RY4 Double vaping liquid
|
Sessions 2-5: Unflavored Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Unflavored vaping liquid
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Puff Topography: Flow Rate
|
25.2 ml per second
Standard Error 2.8
|
27.8 ml per second
Standard Error 2.4
|
24.2 ml per second
Standard Error 1.9
|
33.7 ml per second
Standard Error 2.1
|
31.4 ml per second
Standard Error 2.1
|
33.9 ml per second
Standard Error 2.6
|
30.0 ml per second
Standard Error 2.32
|
28.4 ml per second
Standard Error 3.4
|
28.7 ml per second
Standard Error 3.3
|
28.2 ml per second
Standard Error 2.3
|
25.5 ml per second
Standard Error 2.7
|
29.3 ml per second
Standard Error 2.4
|
24.8 ml per second
Standard Error 2.6
|
27.8 ml per second
Standard Error 2.9
|
SECONDARY outcome
Timeframe: Single Session, Approximately 2 hours in durationPopulation: Mean sensory and subjective effects scores by bout type and flavor condition, Sub-Study A.
Will be assessed by Duke Sensory Scale
Outcome measures
| Measure |
Sessions 2-5: Unflavored Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Unflavored vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Red Oak vaping liquid
|
Sessions 2-5: Red Oak Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Red Oak vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Synthetic Nicotine Liquid Puff Count Directed
n=17 Participants
Mean directed ad lib puff count: Synthetic vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Tobacco Derived vaping liquid
|
Session 6-7: Tobacco Derived Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Tobacco Derived vaping liquid
|
Session 1: Own Brand Puff Duration Ad Lib
n=18 Participants
Mean ad lib puff duration: Own Brand
|
Session 1: Own Brand Puff Duration Directed
n=18 Participants
Mean directed puff duration: Own Brand
|
Sessions 2-5: Cowboy Vaping Liquid Puff Duration Ad Lib
n=17 Participants
Mean ad lib puff duration: Cowboy vaping liquid
|
Sessions 2-5: Cowboy Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: Cowboy vaping liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: RY4 Double Vaping Liquid
|
Sessions 2-5: RY4 Double Vaping Liquid Puff Count Directed
n=17 Participants
Mean directed puff count: RY4 Double vaping liquid
|
Sessions 2-5: Unflavored Vaping Liquid Puff Count Ad Lib
n=17 Participants
Mean ad lib puff count: Unflavored vaping liquid
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Subjective Questionnaires of Product Evaluation
Draw (0 "less draw" - 100 "more draw)
|
75.5 units on a scale
Standard Error 4.2
|
68.8 units on a scale
Standard Error 5.0
|
72.5 units on a scale
Standard Error 4.7
|
71.9 units on a scale
Standard Error 5.0
|
74.2 units on a scale
Standard Error 5.3
|
66.2 units on a scale
Standard Error 6.6
|
74.1 units on a scale
Standard Error 5.2
|
72.3 units on a scale
Standard Error 7.3
|
77.0 units on a scale
Standard Error 5.7
|
69.7 units on a scale
Standard Error 4.4
|
64.1 units on a scale
Standard Error 5.6
|
61.1 units on a scale
Standard Error 6.5
|
71.6 units on a scale
Standard Error 4.5
|
72.9 units on a scale
Standard Error 4.7
|
|
Subjective Questionnaires of Product Evaluation
Pleasantness (-100 "less pleasant" - +100 "more pleasant")
|
37.7 units on a scale
Standard Error 15.7
|
-2.0 units on a scale
Standard Error 14.8
|
22.4 units on a scale
Standard Error 16.2
|
26.2 units on a scale
Standard Error 11.6
|
21.2 units on a scale
Standard Error 12.9
|
1.2 units on a scale
Standard Error 11.6
|
7.5 units on a scale
Standard Error 14.8
|
45.2 units on a scale
Standard Error 12.0
|
33.2 units on a scale
Standard Error 15.9
|
-3.2 units on a scale
Standard Error 15.3
|
-32.6 units on a scale
Standard Error 15.5
|
3.9 units on a scale
Standard Error 13.1
|
-2.5 units on a scale
Standard Error 13.3
|
16.4 units on a scale
Standard Error 15.2
|
|
Subjective Questionnaires of Product Evaluation
Tingling Sensation (0 "less tingling sensation" - 100 "more tingling sensation")
|
45.1 units on a scale
Standard Error 6.3
|
36.2 units on a scale
Standard Error 5.6
|
33.4 units on a scale
Standard Error 5.1
|
27.8 units on a scale
Standard Error 5.3
|
29.8 units on a scale
Standard Error 5.7
|
21.0 units on a scale
Standard Error 5.2
|
29.0 units on a scale
Standard Error 6.1
|
50.2 units on a scale
Standard Error 11.4
|
34.8 units on a scale
Standard Error 8.6
|
34.2 units on a scale
Standard Error 6.6
|
44.4 units on a scale
Standard Error 4.9
|
38.9 units on a scale
Standard Error 6.5
|
44.7 units on a scale
Standard Error 7.8
|
25.4 units on a scale
Standard Error 5.3
|
|
Subjective Questionnaires of Product Evaluation
Product Evaluation Score: Satisfaction (1 "not at all" - 7 "extremely")
|
3.4 units on a scale
Standard Error 0.4
|
3.1 units on a scale
Standard Error 0.4
|
2.9 units on a scale
Standard Error 0.4
|
3.4 units on a scale
Standard Error 0.3
|
3.4 units on a scale
Standard Error 0.3
|
3.1 units on a scale
Standard Error 0.3
|
3.2 units on a scale
Standard Error 0.3
|
4.8 units on a scale
Standard Error 0.4
|
4.2 units on a scale
Standard Error 0.4
|
2.8 units on a scale
Standard Error 0.3
|
2.6 units on a scale
Standard Error 0.4
|
2.7 units on a scale
Standard Error 0.3
|
3.0 units on a scale
Standard Error 0.4
|
3.1 units on a scale
Standard Error 0.4
|
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Subjective Questionnaires of Product Evaluation
Product Evaluaton Sore: Relief (1 "not at all" - 7 "extremely")
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4.1 units on a scale
Standard Error 0.3
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4.5 units on a scale
Standard Error 0.3
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4.5 units on a scale
Standard Error 0.3
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4.8 units on a scale
Standard Error 0.3
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4.7 units on a scale
Standard Error 0.4
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4.4 units on a scale
Standard Error 0.3
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4.6 units on a scale
Standard Error 0.3
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5.3 units on a scale
Standard Error 0.4
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4.7 units on a scale
Standard Error 0.6
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3.9 units on a scale
Standard Error 0.3
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4.4 units on a scale
Standard Error 0.3
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4.0 units on a scale
Standard Error 0.3
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4.2 units on a scale
Standard Error 0.3
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4.3 units on a scale
Standard Error 0.3
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Adverse Events
Session 1: Own Brand Topography Ad Lib
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Session 1: Own Brand Topography Directed
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 2-5: Cowboy Liquid Topography Ad Lib
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 2-5: Cowboy Liquid Vaping Liquid Directed
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 2-5: RY4 Vaping Liquid Topography Ad Lib
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 2-5: RY4 Vaping Liquid Topography Directed
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 2-5: Red Oak Vaping Liquid Topography Ad Lib
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 2-5: Red Oak Vaping Liquid Topography Directed
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 2-5: Unflavored Vaping Liquid Topography Ad Lib
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Unflavored Vaping Liquid Vaping Topography Directed
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 6-7: Synthetic Nicotine Vaping Liquid Topography Ad Lib
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 6-7: Synthetic Vaping Liquid Topography Directed
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 6-7: Tobacco Derived Vaping Liquid Topography Ad Lib
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Sessions 6-7: Tobacco Derived Vaping Liquid Topography Directed
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place