Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
60 participants
INTERVENTIONAL
2023-05-10
2023-10-02
Brief Summary
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Detailed Description
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For this purpose; Group I (control group) 0.5% bupivacaine 20 ml, Group II 0.5% bupivacaine 20 ml+150 mg MgSO4, Group III 0% ,5 bupivacaine 20 ml+2 mg/kg ketamine HCl will be administered. In all groups, the total volume will completed to 25 ml with 0.9% NaCl.
After surgery, hemodynamic values (heart rate, systolic and diastolic blood pressure), oxygen saturation, VAS scores (at rest and effort), Ramsey sedation score, patients satisfaction scores, PCA morphine consumption, additional analgesic requirements, and side effects will be recorded.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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control group
Erector spinae plane block with 20 mL 0.5% bupivacaine
Bupivacain
Bupivacaine is a local anesthetic agent commonly used in ESP block.
magnesium group
Erector spinae plane block with 20 mL 0.5% bupivacaine+150 mg magnesium sulphate
Bupivacain
Bupivacaine is a local anesthetic agent commonly used in ESP block.
Magnesium sulfate
Magnesium is an adjuvant agent that can be added to the local anesthetic agent to increase analgesic effectiveness..
ketamine group
Erector spinae plane block with 20 mL 0.5% bupivacaine+2 mg/kg ketamine
Bupivacain
Bupivacaine is a local anesthetic agent commonly used in ESP block.
Ketamine Hydrochloride
Ketamine Hydrochloride is an also adjuvant agent that can be added to the local anesthetic to increase analgesic effectiveness.
Interventions
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Bupivacain
Bupivacaine is a local anesthetic agent commonly used in ESP block.
Magnesium sulfate
Magnesium is an adjuvant agent that can be added to the local anesthetic agent to increase analgesic effectiveness..
Ketamine Hydrochloride
Ketamine Hydrochloride is an also adjuvant agent that can be added to the local anesthetic to increase analgesic effectiveness.
Eligibility Criteria
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Inclusion Criteria
* voluntarily agree to participate in the study,
* over 18 years old,
* ASA I-III
Exclusion Criteria
* Coagulation disorders or anticoagulant agent therapy,
* Allergy or hypersensitivity to any drug to be will be used in the study,
* Epilepsy,
* High intracranial pressure,
* Unwillingness to participate in the study
* Inability to use the PCA device
18 Years
ALL
Yes
Sponsors
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Cukurova University
OTHER
Responsible Party
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mediha turktan
associate professor
Locations
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Cukurova University
Adana, Adana, Turkey (Türkiye)
Countries
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Other Identifiers
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esp01
Identifier Type: -
Identifier Source: org_study_id
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