Trial Outcomes & Findings for Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs (NCT NCT05849051)

Results Overview

Average quit intention score measured by survey. Quit intention measured with 3 questions, the final quit intention score is a mean of the response to the 3 questions, on a scale of 1 to 4, where 1 indicates low intention to quit, and 4 indicates a high intention to quit.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

1029 participants

Primary outcome timeframe

day 21 (post test)

Results posted on

2025-01-08

Participant Flow

Participants were recruited and screened for study eligiblity online between May and August 2024, and invited to in the study once they were determined to be eligible.

1,114 potential participants began the baseline survey. Of those, 44 did not consent to participate in the study, and 41 did not complete the baseline questionnaire and were not randomized. 1,029 participants were enrolled and randomized in the study.

Participant milestones

Participant milestones
Measure	Newly Developed Warnings With Images Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention Participants do not receive an intervention
Overall Study STARTED	339	346	344
Overall Study COMPLETED	339	346	344
Overall Study NOT COMPLETED	0	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Newly Developed Warnings With Images n=339 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=346 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=344 Participants Participants do not receive an intervention	Total n=1029 Participants Total of all reporting groups
Age, Continuous	43.03 years STANDARD_DEVIATION 10.44 • n=5 Participants	44.48 years STANDARD_DEVIATION 11.73 • n=7 Participants	44.07 years STANDARD_DEVIATION 11.61 • n=5 Participants	43.86 years STANDARD_DEVIATION 11.29 • n=4 Participants
Sex/Gender, Customized Male	175 Participants n=5 Participants	208 Participants n=7 Participants	195 Participants n=5 Participants	578 Participants n=4 Participants
Sex/Gender, Customized Female	163 Participants n=5 Participants	138 Participants n=7 Participants	148 Participants n=5 Participants	449 Participants n=4 Participants
Sex/Gender, Customized Another Gender	1 Participants n=5 Participants	0 Participants n=7 Participants	1 Participants n=5 Participants	2 Participants n=4 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	68 Participants n=5 Participants	50 Participants n=7 Participants	52 Participants n=5 Participants	170 Participants n=4 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	270 Participants n=5 Participants	294 Participants n=7 Participants	291 Participants n=5 Participants	855 Participants n=4 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	1 Participants n=5 Participants	2 Participants n=7 Participants	1 Participants n=5 Participants	4 Participants n=4 Participants
Race/Ethnicity, Customized American Indian or Alaska Native	5 Participants n=5 Participants	4 Participants n=7 Participants	1 Participants n=5 Participants	10 Participants n=4 Participants
Race/Ethnicity, Customized Asian	21 Participants n=5 Participants	13 Participants n=7 Participants	19 Participants n=5 Participants	53 Participants n=4 Participants
Race/Ethnicity, Customized Native Hawaiian/Pacific Islander	0 Participants n=5 Participants	1 Participants n=7 Participants	1 Participants n=5 Participants	2 Participants n=4 Participants
Race/Ethnicity, Customized Black/African American	70 Participants n=5 Participants	70 Participants n=7 Participants	77 Participants n=5 Participants	217 Participants n=4 Participants
Race/Ethnicity, Customized White	203 Participants n=5 Participants	228 Participants n=7 Participants	214 Participants n=5 Participants	645 Participants n=4 Participants
Race/Ethnicity, Customized More than one Race	24 Participants n=5 Participants	20 Participants n=7 Participants	21 Participants n=5 Participants	65 Participants n=4 Participants
Race/Ethnicity, Customized Unknown not reported	16 Participants n=5 Participants	10 Participants n=7 Participants	11 Participants n=5 Participants	37 Participants n=4 Participants
Region of Enrollment United States	339 participants n=5 Participants	346 participants n=7 Participants	344 participants n=5 Participants	1029 participants n=4 Participants

PRIMARY outcome

Timeframe: day 21 (post test)

Population: Participants who responded to the scale at the time point of interest, post test on day 21

Average quit intention score measured by survey. Quit intention measured with 3 questions, the final quit intention score is a mean of the response to the 3 questions, on a scale of 1 to 4, where 1 indicates low intention to quit, and 4 indicates a high intention to quit.

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=311 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=317 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=312 Participants Participants do not receive an intervention
LCC Quit Intentions	2.9 score on a scale Standard Deviation 1.10	2.49 score on a scale Standard Deviation 1.12	2.54 score on a scale Standard Deviation 1.09

SECONDARY outcome

Timeframe: day 1

Population: Participants who responded to the measures at the time point of interest, day 1

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant.

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=264 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=268 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=255 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.75 number of LCCs Standard Deviation 4.09	2.47 number of LCCs Standard Deviation 3.14	2.28 number of LCCs Standard Deviation 2.85

SECONDARY outcome

Timeframe: day 2

Population: Participants who responded to the measures at the time point of interest, day 2

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=268 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=271 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=278 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.43 number of LCCs Standard Deviation 3.09	2.62 number of LCCs Standard Deviation 3.30	2.21 number of LCCs Standard Deviation 2.79

SECONDARY outcome

Timeframe: day 3

Population: Participants who responded to the measures at the time point of interest, day 3

The mean number of little cigars and cigarillos (LCCs) smoked in the past day was reported by participants.

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=279 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=258 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=264 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.56 number of LCCs Standard Deviation 3.17	2.66 number of LCCs Standard Deviation 3.13	2.44 number of LCCs Standard Deviation 2.86

SECONDARY outcome

Timeframe: day 4

Population: Participants who responded to the measures at the time point of interest, day 4

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant.

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=275 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=294 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=289 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.66 number of LCCs Standard Deviation 3.51	3.04 number of LCCs Standard Deviation 4.46	2.50 number of LCCs Standard Deviation 2.95

SECONDARY outcome

Timeframe: day 5

Population: Participants who responded to the measures at the time point of interest, day 5

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=283 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=282 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=273 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.77 number of LCCs Standard Deviation 3.67	3.07 number of LCCs Standard Deviation 4.21	2.43 number of LCCs Standard Deviation 2.78

SECONDARY outcome

Timeframe: day 6

Population: Participants who responded to the measures at the time point of interest, day 6

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=295 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=301 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=291 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.66 number of LCCs Standard Deviation 3.72	3.12 number of LCCs Standard Deviation 4.81	2.20 number of LCCs Standard Deviation 2.64

SECONDARY outcome

Timeframe: day 7

Population: Participants who responded to the measures at the time point of interest, day 7

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=298 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=299 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=293 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.30 number of LCCs Standard Deviation 3.18	2.73 number of LCCs Standard Deviation 4.04	2.33 number of LCCs Standard Deviation 3.49

SECONDARY outcome

Timeframe: day 8

Population: Participants who responded to the measures at the time point of interest, day 8

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=294 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=299 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=294 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.37 number of LCCs Standard Deviation 3.61	2.68 number of LCCs Standard Deviation 4.46	2.28 number of LCCs Standard Deviation 3.13

SECONDARY outcome

Timeframe: day 9

Population: Participants who responded to the measures at the time point of interest, day 9

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=293 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=292 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=298 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.64 number of LCCs Standard Deviation 4.28	2.68 number of LCCs Standard Deviation 4.50	2.43 number of LCCs Standard Deviation 3.27

SECONDARY outcome

Timeframe: day 10

Population: Participants who responded to the measures at the time point of interest, day 10

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=284 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=298 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=284 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.62 number of LCCs Standard Deviation 4.50	2.56 number of LCCs Standard Deviation 4.16	2.39 number of LCCs Standard Deviation 3.27

SECONDARY outcome

Timeframe: day 11

Population: Participants who responded to the measures at the time point of interest, day 11

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=280 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=288 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=284 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.69 number of LCCs Standard Deviation 4.11	2.94 number of LCCs Standard Deviation 4.47	2.47 number of LCCs Standard Deviation 3.23

SECONDARY outcome

Timeframe: day 12

Population: Participants who responded to the measures at the time point of interest, day 12

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=285 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=293 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=284 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.28 number of LCCs Standard Deviation 3.28	2.77 number of LCCs Standard Deviation 4.33	2.46 number of LCCs Standard Deviation 3.01

SECONDARY outcome

Timeframe: day 13

Population: Participants who responded to the measures at the time point of interest, day 13

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=291 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=297 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=295 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.62 number of LCCs Standard Deviation 3.86	2.79 number of LCCs Standard Deviation 4.61	2.50 number of LCCs Standard Deviation 3.38

SECONDARY outcome

Timeframe: day 14

Population: Participants who responded to the measures at the time point of interest, day 14

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=278 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=293 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=288 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.19 number of LCCs Standard Deviation 3.24	2.44 number of LCCs Standard Deviation 4.58	2.24 number of LCCs Standard Deviation 3.47

SECONDARY outcome

Timeframe: day 15

Population: Participants who responded to the measures at the time point of interest, day 15

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=268 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=274 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=267 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.35 number of LCCs Standard Deviation 4.27	2.56 number of LCCs Standard Deviation 4.46	2.26 number of LCCs Standard Deviation 3.39

SECONDARY outcome

Timeframe: day 16

Population: Participants who responded to the measures at the time point of interest, day 16

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=274 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=290 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=283 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.21 number of LCCs Standard Deviation 3.07	2.62 number of LCCs Standard Deviation 4.43	2.35 number of LCCs Standard Deviation 3.57

SECONDARY outcome

Timeframe: day 17

Population: Participants who responded to the measures at the time point of interest, day 17

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=279 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=290 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=286 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.23 number of LCCs Standard Deviation 3.38	2.62 number of LCCs Standard Deviation 4.35	2.38 number of LCCs Standard Deviation 3.58

SECONDARY outcome

Timeframe: day 18

Population: Participants who responded to the measures at the time point of interest, day 18

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=279 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=277 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=272 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.26 number of LCCs Standard Deviation 3.33	2.87 number of LCCs Standard Deviation 4.51	2.47 number of LCCs Standard Deviation 3.36

SECONDARY outcome

Timeframe: day 19

Population: Participants who responded to the measures at the time point of interest, day 19

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=273 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=289 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=284 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.27 number of LCCs Standard Deviation 3.38	2.85 number of LCCs Standard Deviation 4.36	2.38 number of LCCs Standard Deviation 3.39

SECONDARY outcome

Timeframe: day 20

Population: Participants who responded to the measures at the time point of interest, day 20

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=288 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=289 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=283 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.18 number of LCCs Standard Deviation 3.46	2.62 number of LCCs Standard Deviation 4.25	2.36 number of LCCs Standard Deviation 3.40

SECONDARY outcome

Timeframe: day 21 (post test)

Population: Participants who responded to the measures at the time point of interest, day 21 (post test)

The mean number of little cigars and cigarillos (LCCs) smoked in the past day reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=305 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=311 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=306 Participants Participants do not receive an intervention
Number of LCCs Smoked in Past Day	2.13 number of LCCs Standard Deviation 3.30	2.34 number of LCCs Standard Deviation 3.36	2.43 number of LCCs Standard Deviation 4.58

SECONDARY outcome

Timeframe: day 7

Population: Participants who responded to the measures at the time point of interest, day 7

The mean number days that a participant reported smoking little cigars and cigarillos (LCCs) smoked in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=307 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=305 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=302 Participants Participants do not receive an intervention
Number of Days Smoked LCCs in Past Week	3.46 number of days Standard Deviation 2.29	3.58 number of days Standard Deviation 2.31	3.46 number of days Standard Deviation 2.25

SECONDARY outcome

Timeframe: day 14

Population: Participants who responded to the measures at the time point of interest, day 14

The mean number days that a participant reported smoking little cigars and cigarillos (LCCs) smoked in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=286 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=300 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=295 Participants Participants do not receive an intervention
Number of Days Smoked LCCs in Past Week	3.26 number of days Standard Deviation 2.40	3.50 number of days Standard Deviation 2.38	3.45 number of days Standard Deviation 2.28

SECONDARY outcome

Timeframe: day 21 (post test)

Population: Participants who responded to the measures at the time point of interest, day 21 (post test)

The mean number days that a participant reported smoking little cigars and cigarillos (LCCs) smoked in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=312 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=317 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=313 Participants Participants do not receive an intervention
Number of Days Smoked LCCs in Past Week	3.15 number of days Standard Deviation 2.44	3.46 number of days Standard Deviation 2.47	3.41 number of days Standard Deviation 2.29

SECONDARY outcome

Timeframe: day 7

Population: Participants who responded to the measures at the time point of interest, day 7

The mean number of little cigars and cigarillos (LCCs) smoked in the past week reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=307 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=305 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=302 Participants Participants do not receive an intervention
Number of LCCs Smoked in the Past Week	15.66 number of LCCs Standard Deviation 23.13	16.05 number of LCCs Standard Deviation 24.84	13.32 number of LCCs Standard Deviation 17.32

SECONDARY outcome

Timeframe: day 14

Population: Participants who responded to the measures at the time point of interest, day 14

The mean number of little cigars and cigarillos (LCCs) smoked in the past week reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=286 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=300 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=295 Participants Participants do not receive an intervention
Number of LCCs Smoked in the Past Week	14.67 number of LCCs Standard Deviation 22.45	15.35 number of LCCs Standard Deviation 22.37	13.47 number of LCCs Standard Deviation 18.03

SECONDARY outcome

Timeframe: day 21 (post test)

Population: Participants who responded to the measures at the time point of interest, day 21 (post test)

The mean number of little cigars and cigarillos (LCCs) smoked in the past week reported by participant

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=311 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=317 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=313 Participants Participants do not receive an intervention
Number of LCCs Smoked in the Past Week	14.11 number of LCCs Standard Deviation 20.30	15.89 number of LCCs Standard Deviation 22.38	13.93 number of LCCs Standard Deviation 18.94

SECONDARY outcome

Timeframe: day 7

Population: Participants who responded to the measures at the time point of interest, day 7

The mean number of little cigars and cigarillos (LCCs) that participants reported butting out in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=300 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=298 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=293 Participants Participants do not receive an intervention
Number of LCCs Butted Out in the Past Week	4.24 number of LCCs Standard Deviation 7.86	3.64 number of LCCs Standard Deviation 18.09	3.03 number of LCCs Standard Deviation 6.51

SECONDARY outcome

Timeframe: day 14

Population: Participants who responded to the measures at the time point of interest, day 14

The mean number of little cigars and cigarillos (LCCs) that participants reported butting out in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=276 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=295 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=287 Participants Participants do not receive an intervention
Number of LCCs Butted Out in the Past Week	3.11 number of LCCs Standard Deviation 5.22	3.48 number of LCCs Standard Deviation 15.53	2.59 number of LCCs Standard Deviation 5.71

SECONDARY outcome

Timeframe: day 21 (post test)

Population: Participants who responded to the measures at the time point of interest, day 21 (post test)

The mean number of little cigars and cigarillos (LCCs) that participants reported butting out in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=304 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=311 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=305 Participants Participants do not receive an intervention
Number of LCCs Butted Out in the Past Week	3.11 number of LCCs Standard Deviation 5.41	3.46 number of LCCs Standard Deviation 14.93	2.81 number of LCCs Standard Deviation 5.67

SECONDARY outcome

Timeframe: day 7

Population: Participants who responded to the measures at the time point of interest, day 7

The mean number of little cigars and cigarillos (LCCs) that participants reported forgoing in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=307 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=305 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=302 Participants Participants do not receive an intervention
Number of LCCs Forgone in the Past Week	3.85 number of LCCs Standard Deviation 5.24	3.64 number of LCCs Standard Deviation 17.62	2.88 number of LCCs Standard Deviation 4.83

SECONDARY outcome

Timeframe: day 14

Population: Participants who responded to the measures at the time point of interest, day 14

The mean number of little cigars and cigarillos (LCCs) that participants reported forgoing in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=286 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=300 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=295 Participants Participants do not receive an intervention
Number of LCCs Forgone in the Past Week	6.79 number of LCCs Standard Deviation 30.85	3.47 number of LCCs Standard Deviation 15.39	2.81 number of LCCs Standard Deviation 4.31

SECONDARY outcome

Timeframe: day 21 (post test)

Population: Participants who responded to the measures at the time point of interest, day 21 (post test)

The mean number of little cigars and cigarillos (LCCs) that participants reported forgoing in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=311 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=317 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=313 Participants Participants do not receive an intervention
Number of LCCs Forgone in the Past Week	5.69 number of LCCs Standard Deviation 14.67	4.30 number of LCCs Standard Deviation 15.95	3.46 number of LCCs Standard Deviation 7.30

SECONDARY outcome

Timeframe: day 7

Population: Participants who responded to the measures at the time point of interest, day 7

The number and percent of participants who reported trying to quit smoking little cigars and cigarillos (LCCs) in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=307 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=305 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=301 Participants Participants do not receive an intervention
LCC Quit Attempts in Past Week	108 Participants	61 Participants	62 Participants

SECONDARY outcome

Timeframe: day 14

Population: Participants who responded to the measures at the time point of interest, day 14

The number and percent of participants who reported trying to quit smoking little cigars and cigarillos (LCCs) in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=286 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=299 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=295 Participants Participants do not receive an intervention
LCC Quit Attempts in Past Week	102 Participants	71 Participants	66 Participants

SECONDARY outcome

Timeframe: day 21 (post test)

Population: Participants who responded to the measures at the time point of interest, day 21 (post test)

The number and percent of participants who reported trying to quit smoking little cigars and cigarillos (LCCs) in the past week

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=311 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=317 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=312 Participants Participants do not receive an intervention
LCC Quit Attempts in Past Week	134 Participants	90 Participants	86 Participants

SECONDARY outcome

Timeframe: day 7

Population: Participants who responded to the scale at the time point of interest, day 7

Average quit intention score measured by survey. Quit intention measured with 3 questions, the final quit intention score is a mean of the response to the 3 questions, on a scale of 1 to 4, where 1 indicates low intention to quit, and 4 indicates a high intention to quit.

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=307 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=305 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=301 Participants Participants do not receive an intervention
LCC Quit Intentions	2.76 score on a scale Standard Deviation 1.07	2.33 score on a scale Standard Deviation 1.05	2.46 score on a scale Standard Deviation 1.04

SECONDARY outcome

Timeframe: day 14

Population: Participants who responded to the scale at the time point of interest, day 14

Average quit intention score measured by survey. Quit intention measured with 3 questions, the final quit intention score is a mean of the response to the 3 questions, on a scale of 1 to 4, where 1 indicates low intention to quit, and 4 indicates a high intention to quit.

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=286 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=299 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention n=295 Participants Participants do not receive an intervention
LCC Quit Intentions	2.82 score on a scale Standard Deviation 1.08	2.42 score on a scale Standard Deviation 1.09	2.51 score on a scale Standard Deviation 1.04

SECONDARY outcome

Timeframe: day 21 (post test)

Population: Only Newly developed warnings with images and FDA proposed text-only warnings were included. Participants who responded to the measures at the time point of interest, day 21 (post test)

Mean self-reported learning reported by participants. Self-reported learning measured with one item on a 1 to 5 scale, where 1 indicates no learning, and 5 indicates a great deal of learning from the warnings in the study. Self reported learning is only measured in conditions 1 and 2, the conditions that receive warnings.

Outcome measures

Outcome measures
Measure	Newly Developed Warnings With Images n=311 Participants Participants receive newly developed warnings intervention Newly developed warnings with images at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning developed by the study team that includes an image. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	FDA Proposed Text-only Warnings n=316 Participants Participants receive FDA proposed text only warning intervention FDA proposed text-only warnings at 30% size: On study days 1-6, 8-13 and 15-20, participants in this condition will view an image of a little cigar and cigarillo package with a warning proposed by the FDA which is text only. The warnings will take up 30% of the package. Participants will view a total of 6 different warnings over the course of 6 days each week, this will be repeated 3 times during the study, resulting in a total of 18 exposures. Participants will be required to view the warning for at least 5 seconds.	Control Group, no Intervention Participants do not receive an intervention
Self Reported Learning	4.14 units on a scale Standard Deviation 1.01	3.60 units on a scale Standard Deviation 1.18	—

Adverse Events

Newly Developed Warnings With Images

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

FDA Proposed Text-only Warnings

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Control Group, no Intervention

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Adam O Goldstein

UNC Lineberger Comprehensive Cancer Center

Phone: 919-270-6491

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place