Assisting Pulmonary Disease Diagnosis With Ophthalmic Artificial Intelligence Technology

NCT ID: NCT05847894

Last Updated: 2025-05-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-29

Study Completion Date

2026-05-31

Brief Summary

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This study intends to collect ophthalmologic examination results, pulmonary examination results and related indexes from patients with pulmonary disease and control populations, and combine big data analysis and artificial intelligence technology to explore whether new methods can be provided for early screening strategies for pulmonary disease with the aid of ophthalmologic examination, and thus assist in identifying the types of pulmonary disease and determining disease prognosis.

Detailed Description

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Conditions

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Pulmonary Diseases Ophthalmological Diagnostic Techniques Artificial Intelligence

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Test group

Individuals with one or more pulmonary diseases

Ophthalmic examination

Intervention Type DIAGNOSTIC_TEST

Various ophthalmic examination modalities, including slit lamp photography, fundus photography, optical coherence tomography imaging and optical coherence tomography angiography, etc.

Pulmonary Examination

Intervention Type DIAGNOSTIC_TEST

Various pulmonary examination modalities, including radiography, chest CT, pulmonary function measurement, etc.

Control group

Individuals who do not suffer from pulmonary diseases

Ophthalmic examination

Intervention Type DIAGNOSTIC_TEST

Various ophthalmic examination modalities, including slit lamp photography, fundus photography, optical coherence tomography imaging and optical coherence tomography angiography, etc.

Pulmonary Examination

Intervention Type DIAGNOSTIC_TEST

Various pulmonary examination modalities, including radiography, chest CT, pulmonary function measurement, etc.

Interventions

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Ophthalmic examination

Various ophthalmic examination modalities, including slit lamp photography, fundus photography, optical coherence tomography imaging and optical coherence tomography angiography, etc.

Intervention Type DIAGNOSTIC_TEST

Pulmonary Examination

Various pulmonary examination modalities, including radiography, chest CT, pulmonary function measurement, etc.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Those aged ≥18 years; or those aged \<18 years who can cooperate with the relevant examination and are accompanied and informed by a guardian;
* People with respiratory-related diseases who were to undergo pulmonary examination, or those who volunteered to participate in the trial through publicity recruitment;
* expected survival time of 3 months or more;
* Those with no previous serious underlying disease and no history of serious eye disease;
* Those who can cooperate with ophthalmologic and pulmonary-related examinations and have regular follow-up examinations;
* Those who gave informed consent to the study prior to the trial and voluntarily signed the informed consent form;
* Other conditions that can be included in the study as judged by the investigator.

Exclusion Criteria

* Patients who are unable to complete ophthalmology or pulmonary-related examinations and regular follow-ups due to serious diseases, trauma or surgery (serious ophthalmology diseases such as extremely poor vision that cannot be fixed, ocular atrophy, severe refractive interstitial clouding that prevents fundus photography, etc.);
* People with poor compliance due to various reasons such as alcohol or drug dependence, or mental disorders;
* Those without informed consent;
* Other conditions judged by the investigator to be unsuitable for participation in the trial.
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The First Affiliated Hospital of Guangzhou Medical University

OTHER

Sponsor Role collaborator

Shenzhen Third People's Hospital

OTHER

Sponsor Role collaborator

Guangzhou Kindness Health Care Center (Guangzhou Jiubang Shanxin Clinic Ltd), Guangzhou, China

UNKNOWN

Sponsor Role collaborator

Zhongshan Ophthalmic Center, Sun Yat-sen University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, China

Site Status RECRUITING

Guangzhou Kindness Health Care Center (Guangzhou Jiubang Shanxin Clinic Ltd)

Guangzhou, Guangdong, China

Site Status RECRUITING

the First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

Site Status RECRUITING

Shenzhen Third People's Hospital

Shenzhen, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Weixing Zhang, M.D.

Role: CONTACT

8615602211660

Facility Contacts

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Haotian Lin, M.D., Ph.D

Role: primary

8613802793086

Xun Wang, M.D., Ph.D

Role: backup

8615017541549

Bin Xu

Role: primary

+86 13925155511

Wenhua Liang, M.D.

Role: primary

Weiyi Lai

Role: primary

+86 13556125580

Other Identifiers

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2023KYPJ111

Identifier Type: -

Identifier Source: org_study_id

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