Evaluation of Infrared Thermal Imaging in Diagnosis of OSAHS in Children

NCT ID: NCT05830227

Last Updated: 2023-04-26

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 80 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-04-30
• Study Completion Date: 2025-12-31

Brief Summary

OSAHS is a common sleep breathing disorder in children, with the same incidence as childhood asthma, and is mainly caused by upper airway stenosis caused by tonsil/adenoid hyperplasia. Clinical findings show that children with OSAHS often present rhinitis symptoms and like rubbing eyes, but there is no evidence to suggest a correlation. Children with OSAHS suffer from recurrent hypoxemia during sleep, and the existing detection methods such as lateral nasopharyngeal radiographs and electronic nasopharyngoscopy can only reflect the structural and morphological changes of the oral, nasal and pharyngeal tissues, but cannot prove their functional status. Previous studies have found that infrared thermal imaging can reflect the oral, nasal and pharyngeal inflammation of patients, and the infrared expression of patients' frontal region and eyes can also reflect the physiological changes caused by sleep deprivation.

Detailed Description

In this project, the children were divided into four groups: primary snoring, critical OSAHS, mild OSAHS and moderate to severe OSAHS, and the tests were completed, including lateral nasopharyngeal radiographs, infrared detection of oropharynx and pharynx, infrared detection of frontal area and eye area, intelligence and behavior scale assessment, etc. Furthermore, the correlation between infrared detection and obstructive sleep apnea hypopnea index, peripheral blood oxygen saturation, adenoid hyperplasia degree of nasopharyngeal lateral film as parameters were analyzed, and the sensitivity and specificity of infrared detection was determined to confirm the diagnostic value of OSAHS. It provides a theoretical basis for finding a convenient, non-damaging, non-radiation, visual and suitable for children functional image detection method.

Conditions

Infrared-thermal-imaging

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Primary snoring group

Primary snoring group

No interventions assigned to this group

Critical OSAHS group

Critical OSAHS group

No interventions assigned to this group

Mild OSAHS group

Mild OSAHS group

No interventions assigned to this group

Moderate to severe OSAHS group

Moderate to severe OSAHS group

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Children ages 2 to 14 with SDB related symptoms

Exclusion Criteria

• 1) Congenital abnormalities of the nose and throat or airway;

2) craniofacial deformity

3) Neuromuscular dysregulation

4) History of adenoids and/or tonsillectomy.

• Minimum Eligible Age: 2 Years
• Maximum Eligible Age: 14 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

State Key Laboratory of Respiratory Disease

OTHER

Sponsor Role: lead

Responsible Party

Lijun Zeng

Guangzhou Institute of Respiratory Disease

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Lijun Zeng [lzeng]

Guangdong, Uangdong, China

Site Status: RECRUITING

Countries

China

Central Contacts

Lijun Z [lzeng], visiting staff

Role: CONTACT

865391757@qq.com

13450360939 ext. Lijun Zeng

Facility Contacts

Lijun Z [lzeng]

Role: primary

865391757@qq.com

13450360939 ext. Lijun Zeng

Other Identifiers

GuangzhouIRD

Identifier Type: -

Identifier Source: org_study_id