Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
200 participants
OBSERVATIONAL
2022-01-01
2026-01-01
Brief Summary
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Detailed Description
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Pathological fractures should be examined and managed with a different perspective. They usually cannot be healed by conservative methods and require surgical intervention. The primary goals of surgical intervention are to relieve pain and mobilize the patient as soon as possible.
The aim of the study is to compare the short-term functional endoprosthetic recontruction, intramedullary nailing and open reduction internal fixation.
The primary tumor of the patient, applied chemotherapy and radiotherapy, Mirel risk score, Charlson comorbidity index, and PathFx 3.0 survival will be evaluated preoperatively.
The type of the operation will be decided at the multidisciplinary tumor council of ankara University.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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endoprosthetic reconstruction
This is the group of patients with metastatic pathologic fractures treated with endoprosthesis. For example, proximal femur prosthesis for femoral neck fractures.
endoprosthetic reconstruction
This is a type of surgery in which the affected part of the bone and joint is removed, and replaced by a prosthesis.
intramedullary nail
This is the group of patients with metastatic pathologic fractures treated with intramedullary nail, and additional bone cement if needed. For example, proximal femur nail for trochanteric fractures, or long femoral nail for femoral shaft fractures.
Intramedullary nailing
This is a type of surgery in which the affected bone is stabilized by a nail. The affected part could be removed or retained. If removed, the defect is filled with bone cement.
open reduction internal fixation with plate and screws
This is the group of patients with metastatic pathologic fractures treated with open reduction internal fixation; with plates and screws. For example, reconstruction plates for pelvic fractures or 3.5 locking compression plates for humeral or femur shaft fractures.
Open reduction internal fixation with plate and screws
This is a type of surgery in which the affected part of the bone is visualized completely, after the reduction is achieved, the fixation is provided with appropriate plates and screws. Again the affected part could be removed or retained. If removed, the defect is filled with bone cement.
Interventions
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endoprosthetic reconstruction
This is a type of surgery in which the affected part of the bone and joint is removed, and replaced by a prosthesis.
Intramedullary nailing
This is a type of surgery in which the affected bone is stabilized by a nail. The affected part could be removed or retained. If removed, the defect is filled with bone cement.
Open reduction internal fixation with plate and screws
This is a type of surgery in which the affected part of the bone is visualized completely, after the reduction is achieved, the fixation is provided with appropriate plates and screws. Again the affected part could be removed or retained. If removed, the defect is filled with bone cement.
Eligibility Criteria
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Inclusion Criteria
* operated via endoprosthesis, intramedullary nail or plate \& screws
Exclusion Criteria
* conservative management
* neuromuscular disease
* periprosthetic fractures
* less than 1 month follow up
ALL
No
Sponsors
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Ankara University
OTHER
Responsible Party
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Merve Dursun Savran, MD
MD
Locations
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Ankara University Medical Faculty
Ankara, altindag, Turkey (Türkiye)
Countries
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Facility Contacts
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Other Identifiers
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AnkaraUniOrtho
Identifier Type: -
Identifier Source: org_study_id
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