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Longitudinal Study of Chronic Postsurgical Pain in Children and Adolescents

NCT ID: NCT05816174

Last Updated: 2024-12-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

281 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-01

Study Completion Date

2027-01-31

Brief Summary

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Chronic postsurgical pain is defined as pain that develops or intensifies following a surgical procedure. After major surgery, around 20% of children and adolescents develop chronic postsurgical pain, and, as part of it, negative consequences on their quality of life. Emotion-related factors such as the variability of emotions, how emotions are regulated, and how well someone is able to differentiate between different emotions have in part been studied in other types of chronic pain. To date, no study examined emotion-related factors in the development and maintenance of chronic postsurgical pain. This observational study includes five assessment time points, one before and four after major surgery, with the goal to identify emotion-related factors that increase or decrease the risk for the development of chronic postsurgical pain.

Detailed Description

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Conditions

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Chronic Post Operative Pain

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Children and adolescents aged between 8 and 18 years
* Planned orthopedic surgery requiring in-patient care in one of the participating children's hospitals
* Able to read and understand German

Exclusion Criteria

* Serious comorbid health condition (e.g., cancer, severe neurological impairment, chronic illness requiring daily medication)
* Prior major orthopedic surgery (e.g., prior spine surgery)
* Parent/caregiver and child not able to read and understand German
Minimum Eligible Age

8 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Zurich

OTHER

Sponsor Role collaborator

Helen Koechlin

OTHER

Sponsor Role lead

Responsible Party

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Helen Koechlin

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Helen Koechlin, PhD

Role: PRINCIPAL_INVESTIGATOR

University Children's Hospital, Zurich

Locations

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University Children's Hospital Basel

Basel, , Switzerland

Site Status RECRUITING

University Children's Hospital Zurich

Zurich, , Switzerland

Site Status RECRUITING

University Hospital Balgrist

Zurich, , Switzerland

Site Status RECRUITING

Countries

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Switzerland

Central Contacts

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Helen Koechlin, PhD

Role: CONTACT

Phone: 4144 266 83 36

Email: [email protected]

Jana Hochreuter, MSc

Role: CONTACT

Email: [email protected]

Facility Contacts

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Carol-Claudius Hasler, Prof

Role: primary

Helen Koechlin, PhD

Role: primary

Jana Hochreuter, MSc.

Role: backup

Thomas Dreher, Prof

Role: primary

References

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Hochreuter J, Dreher T, Hasler CC, Canonica S, Locher C, Held U, Rabbitts J, Koechlin H. Longitudinal Resilience and Risk Factors in Pediatric Postoperative Pain (LORRIS): Protocol for a Prospective Longitudinal Swiss University Children's Hospitals-Based Study. BMJ Open. 2024 Mar 28;14(3):e080174. doi: 10.1136/bmjopen-2023-080174.

Reference Type BACKGROUND
PMID: 38548365 (View on PubMed)

Other Identifiers

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LORRIS

Identifier Type: -

Identifier Source: org_study_id