Prevention and Rehabilitation of Stroke in Uganda

NCT ID: NCT05807269

Last Updated: 2025-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-01

Study Completion Date

2026-03-31

Brief Summary

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Stroke is increasing in low-income countries in Africa, and knowledge is lacking on risk factors and how to prevent stroke as well as how to best use the resources for rehabilitation after stroke which are very limited. Knowledge generation within this area is therefore urgently needed. This collaboration between the research group HELD (Health and Everyday Life among people with neurological Disorders), Karolinska Institutet (KI) and the research surveillant site Africa Medical and Behavioral Sciences Organization (AMBSO) population health surveillance (PHS), will create substantial research opportunities to develop and improve prevention and rehabilitation for stroke, which is in line with the sustainable development goals to reduce the prevalence and mortality rates due to NCDs. AMBSO is collecting data from 17 000 households on many potential risk factors for stroke. Questions about stroke primary and secondary prevention of stroke and impact of stroke or need of rehabilitation could be added to the existing questionnaires such as the validated Ugandan version of the Stroke Impact Scale. This is intended to fulfill the aim of the network which is to increase the knowledge of occurrence and consequences of NCDs with a specific focus on stroke, which will be valuable for the development of preventive healthcare policy documents and guidelines for appropriate prevention strategies and rehabilitation interventions.

Research questions in relation to NCDs with focus on stroke prevention and rehabilitation:

* How many cases (prevalence) are reported in the targeted study sites and what is the mortality rate (incidence) that can specifically relate to stroke?
* How does stroke and other NCDs affect and impact the quality of life for persons living in Uganda?
* Which factors impact the recovery process after stroke?
* What sort of rehabilitation is needed in the study areas for persons affected by stroke? In addition, risk factors of stroke such as diabetes and hypertension will be mapped.

Detailed Description

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Conditions

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Stroke

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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People with stroke

Participants with stroke or risk factors for stroke

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Stroke
* Risk factors for stroke: hypertension, diabetes, HIV, malaria, physical inactivity, obesity

Exclusion Criteria

* Not having had stroke and/or having no risk factor for stroke
Minimum Eligible Age

13 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Swedish Research Council

OTHER_GOV

Sponsor Role collaborator

Karolinska Institutet

OTHER

Sponsor Role lead

Responsible Party

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Gunilla Eriksson

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gunilla Eriksson, PhD

Role: PRINCIPAL_INVESTIGATOR

Karolinska Institutet

Locations

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AMBSO, Hoima

Hoima, , Uganda

Site Status RECRUITING

AMBSO, Wakiso

Kampala, , Uganda

Site Status RECRUITING

Countries

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Uganda

Central Contacts

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Gunilla Eriksson, PhD

Role: CONTACT

+46702216924

Facility Contacts

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Conrald Kalibagwa

Role: primary

Conrald Kalibagwa

Role: primary

Other Identifiers

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2022-04303

Identifier Type: -

Identifier Source: org_study_id

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