Use of Virtual Reality Goggles During Chemotherapy Infusion to Reduce Anxiety-Related Symptoms

NCT ID: NCT05793957

Last Updated: 2023-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-20

Study Completion Date

2023-09-28

Brief Summary

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This clinical trial evaluates the use of virtual reality (VR) goggles during chemotherapy infusion to reduce anxiety-related symptoms in patients with head and neck, thoracic, hematologic, and breast cancers. Virtual reality headsets provide the ability for users to explore a simulated, three-dimensional environment with which users can interact. In virtual reality users can play interactive games, enjoy relaxing experiences, and watch immersive videos. The use of VR goggles may help with anxiety management during chemotherapy infusion.

Detailed Description

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PRIMARY OBJECTIVE:

I. To evaluate the effectiveness of VR therapy in reducing severity of anxiety symptoms during chemotherapy infusion, compared to participants utilizing a smartphone as a control.

SECONDARY OBJECTIVES:

I. To evaluate whether there is a short-term effect of VR use in anxiety levels.

II. To assess participant satisfaction with their chemotherapy infusion experience in the control and treatment groups.

EXPLORATORY OBJECTIVE:

I. To assess participants' reported adverse effects associated with VR headset use.

OUTLINE: Patients are randomized to 1 of 2 groups.

GROUP 1: Patients use VR during chemotherapy infusion on study.

GROUP 2: Patients use smartphone during chemotherapy infusion on study.

Conditions

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Hematopoietic and Lymphoid System Neoplasm Malignant Breast Neoplasm Malignant Head and Neck Neoplasm Malignant Solid Neoplasm Malignant Thoracic Neoplasm

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Group 1 (VR)

Patients use VR during chemotherapy infusion on study.

Group Type EXPERIMENTAL

Questionnaire Administration

Intervention Type OTHER

Ancillary studies

Virtual Technology Intervention

Intervention Type OTHER

Use VR headset

Group 2 (Smartphone)

Patients use smartphone during chemotherapy infusion on study.

Group Type ACTIVE_COMPARATOR

Questionnaire Administration

Intervention Type OTHER

Ancillary studies

Telephone-Based Intervention

Intervention Type BEHAVIORAL

Use smartphone

Interventions

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Questionnaire Administration

Ancillary studies

Intervention Type OTHER

Telephone-Based Intervention

Use smartphone

Intervention Type BEHAVIORAL

Virtual Technology Intervention

Use VR headset

Intervention Type OTHER

Other Intervention Names

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Virtual Reality Intervention Virtual Technology

Eligibility Criteria

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Inclusion Criteria

* English speaking: Ability to interact with virtual reality content may be impacted by inability to understand English; moreover, paper questionnaires will only be provided in English.
* Older than 18 years of age, and younger than 89 years of age. All sexes/gender identities and members of all races and ethnic groups will be included.
* Planned to receive chemotherapy infusion for head and neck, breast, thoracic, and hematologic cancers at the Oregon Health \& Science University (OHSU) South Waterfront Center for Health \& Healing building 2 (there are no restrictions related to prior chemotherapy infusions or other cancer treatments).
* Chemotherapy treatment lasting at least 10 minutes.
* Ability to understand and willingness to sign a written informed consent document.

Exclusion Criteria

* Social or psychiatric conditions that may interfere with compliance.
* Reconstruction, incisions, wounds, wound care, or injury that impact the ability to place on the VR headset. This would limit the ability to utilize the VR headset.
* History of seizure or epilepsy.
* History of vertigo or persistent dizziness.
* Use of cardiac pacemaker, requirement for hearing aid on at all times, or have defibrillators.
* Children.
* Pregnant women.
* Decisionally impaired adults.
* Prisoners.
Minimum Eligible Age

18 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Oregon Health and Science University

OTHER

Sponsor Role collaborator

OHSU Knight Cancer Institute

OTHER

Sponsor Role lead

Responsible Party

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Ryan Li, MD

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ryan J Li

Role: PRINCIPAL_INVESTIGATOR

OHSU Knight Cancer Institute

Locations

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OHSU Knight Cancer Institute

Portland, Oregon, United States

Site Status

Countries

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United States

Other Identifiers

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NCI-2023-01954

Identifier Type: REGISTRY

Identifier Source: secondary_id

STUDY00025461

Identifier Type: OTHER

Identifier Source: secondary_id

STUDY00025461

Identifier Type: -

Identifier Source: org_study_id