Public Health Impact of Unilateral Spatial Neglect

NCT ID: NCT05792969

Last Updated: 2023-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

168 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-02-07

Study Completion Date

2024-11-30

Brief Summary

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This multi-center project aims to quantify the socio-medical costs associated with Unilateral Spatial Neglect (USN) resulting from acquired brain injury (stroke) and to measure the effects of USN rehabilitation on functional autonomy, quality of life and psychological well-being of patients affected by this syndrome, considering the repercussions on a psychological level and on the quality of life of caregivers.

To this end, the experimenters will administer to right brain-injured patients - with (Experimental Group) or without (Control Group) USN - who undertook a rehabilitation process, a series of questionnaires: Activities of daily living (ADL), Barthel Index; Instrumental activities of daily living scale (I-ADL:), the Health Related Quality of Life questionnaire (EQ-5D-5L), the Geriatric Depression Scale (GDS), and the State-Trait Anxiety Inventory (STAI-Y). The aforementioned tests will be administered before the start of the rehabilitation (baseline) and after one month, 3, 6 and 12 months after the end of the rehabilitation. The impact of USN and its treatment on the psycho-physical well-being of the caregiver will be measured through the Caregiver Burden Inventory questionnaire, which will be administered with the same timing (baseline, 1-3-6-12 months after rehabilitation). The costs of USN will be surveyed through an ad-hoc questionnaire, which includes a version intended for patients and one for caregivers, in order to identify the resources consumed due to the disease and the expenses taken during the observation period, to be estimated subsequently in monetary terms (€).

Detailed Description

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Conditions

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Spatial Neglect

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Stroke patients with USN and their caregivers

Functional measures and public health outcomes

Intervention Type BEHAVIORAL

Questionnaires:

* Activities of daily living - ADL
* Barthel Index
* Instrumental activities of daily living- IADL
* Health Related Quality of Life - EQ-5D-5L
* Geriatric Depression Scale (GDS)
* State-Trait Anxiety Inventory - STAI-Y)
* Caregiver Burden Inventory questionnaire (CBI)

Stroke patients without USN and their caregivers

Functional measures and public health outcomes

Intervention Type BEHAVIORAL

Questionnaires:

* Activities of daily living - ADL
* Barthel Index
* Instrumental activities of daily living- IADL
* Health Related Quality of Life - EQ-5D-5L
* Geriatric Depression Scale (GDS)
* State-Trait Anxiety Inventory - STAI-Y)
* Caregiver Burden Inventory questionnaire (CBI)

Interventions

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Functional measures and public health outcomes

Questionnaires:

* Activities of daily living - ADL
* Barthel Index
* Instrumental activities of daily living- IADL
* Health Related Quality of Life - EQ-5D-5L
* Geriatric Depression Scale (GDS)
* State-Trait Anxiety Inventory - STAI-Y)
* Caregiver Burden Inventory questionnaire (CBI)

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* age \> 18 years;
* right brain injury due to stroke (of ischemic or hemorrhagic origin);
* Disease duration ≥ 10 days;
* Participation to a rehabilitation program;

For stroke patients with USN:

\- clinical diagnosis of USN, placed by the specialist of reference, on the basis of clinical indicators and the results obtained by the patient in the routine neuropsychological evaluation (by means of a battery of standardized psychometric tests calibrated in the Italian population).

Exclusion Criteria

* Other brain disorders
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istituto Auxologico Italiano

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Istituto Auxologico Italiano IRCCS

Milan, Lombardy, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Nadia Bolognini, PhD

Role: CONTACT

Phone: +39025821

Email: [email protected]

Facility Contacts

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Nadia Bolognini, PhD

Role: primary

Other Identifiers

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25C123

Identifier Type: -

Identifier Source: org_study_id