Radicle Health1: A Study of Health and Wellness Formulations and Their Effects on Overall Health

NCT ID: NCT05783232

Last Updated: 2023-11-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

1494 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-03-21

Study Completion Date

2023-10-27

Brief Summary

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A randomized, blinded, placebo-controlled study of health and wellness product formulations and their effects on overall health

Detailed Description

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This is a randomized, blinded, placebo-controlled study conducted with adult participants, age 21 and older and residing in the United States.

Eligible participants will (1) endorse a desire for better health during screening; (2) indicate an interest in taking a health and wellness product to potentially help improve their health, and (3) express acceptance in taking a product and not knowing its formulation until the end of the study.

Participants with known liver or kidney disease, heavy drinkers, and those who report they are pregnant, trying to become pregnant, or breastfeeding will be excluded. Those taking certain medications will be excluded.

Self-reported data will be collected electronically from eligible participants over 5 weeks. Participant reports of health indicators will be collected during baseline, throughout the active period of study product use, and in a final survey. All study assessments will be electronic; there are no in-person visits or assessments for this real-world evidence study.

Conditions

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Sleep Pain Depression Anxiety

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants will be stratified based on gender at birth then randomized to one of the study arm
Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Investigators
The investigator is blinded to the participants assigned study products. Participants are blinded to the study product they received.

Study Groups

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Placebo Control 1 Capsules

Health Product Form 1 Capsules - control

Group Type PLACEBO_COMPARATOR

Placebo Control Form 1 Capsules

Intervention Type DIETARY_SUPPLEMENT

Participants will use their Placebo Control Form 1 Capsules as directed for a period of 4 weeks.

Active Product 1.1 Capsules

Health Product Form 1 Capsules - active product 1

Group Type EXPERIMENTAL

Health Active Study Product 1.1 Capsules

Intervention Type DIETARY_SUPPLEMENT

Participants will use their Radicle Health Active Study Product 1.1 Capsules as directed for a period of 4 weeks.

Active Product 1.2 Capsules

Health Product Form 1 Capsules - active product 2

Group Type EXPERIMENTAL

Health Active Study Product 1.2 Capsules

Intervention Type DIETARY_SUPPLEMENT

Participants will use their Radicle Health Active Study Product 1.2 Capsules as directed for a period of 4 weeks.

Active Product 1.3 Capsules

Health Product Form 1 Capsules - active product 3

Group Type EXPERIMENTAL

Health Active Study Product 1.3 Capsules

Intervention Type DIETARY_SUPPLEMENT

Participants will use their Radicle Health Active Study Product 1.3 Capsules as directed for a period of 4 weeks.

Interventions

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Placebo Control Form 1 Capsules

Participants will use their Placebo Control Form 1 Capsules as directed for a period of 4 weeks.

Intervention Type DIETARY_SUPPLEMENT

Health Active Study Product 1.1 Capsules

Participants will use their Radicle Health Active Study Product 1.1 Capsules as directed for a period of 4 weeks.

Intervention Type DIETARY_SUPPLEMENT

Health Active Study Product 1.2 Capsules

Participants will use their Radicle Health Active Study Product 1.2 Capsules as directed for a period of 4 weeks.

Intervention Type DIETARY_SUPPLEMENT

Health Active Study Product 1.3 Capsules

Participants will use their Radicle Health Active Study Product 1.3 Capsules as directed for a period of 4 weeks.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* 21 years of age and older
* Resides in the United States
* Endorses: a desire for better sleep and/or focus, less pain, less feelings of stress, depression, and/or anxiety, and/or more energy (less fatigue)
* Expresses a willingness to take a study product that may contain cannabinoids (or placebo) and not know the product identity until the end of the study

Exclusion Criteria

* Reports being pregnant, trying to become pregnant, or breastfeeding
* Unable to provide a valid physical shipping address and mobile phone number
* Reports a diagnosis of liver or kidney disease
* Reports being a heavy drinker (defined as drinking 3 or more alcoholic beverages per day)
* Reports current enrollment in a clinical trial
* The QOL score greater than 5 during enrollment
* Unable to read and understand English
* Lack of reliable daily access to the internet
* Reports taking any medication that warns against grapefruit consumption
* Reports current or recent (within 3 months) use of chemotherapy, immunotherapy, or oral anti-infectives (antibiotics, antifungals, antivirals) to treat an acute infection
Minimum Eligible Age

21 Years

Maximum Eligible Age

105 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Radicle Science

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Emily K. Pauli, PharmD

Role: PRINCIPAL_INVESTIGATOR

Radicle Science Inc.

Locations

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Radicle Science, Inc

Del Mar, California, United States

Site Status

Countries

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United States

Related Links

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http://radiclescience.com

Radicle Science, Inc

Other Identifiers

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RADX-22D07

Identifier Type: -

Identifier Source: org_study_id