A 24-week Single-blind Trial of Prevention of Hand Eczema in Cleaners

NCT ID: NCT05763914

Last Updated: 2023-09-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

234 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-11-14

Study Completion Date

2023-06-24

Brief Summary

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This study aims to investigate the effectiveness of picture-based prevention education among professional hospital cleaners in relation to hand eczema. This is a single-blinded randomized clinical trial including hospital cleaners at three different hospitals.

Detailed Description

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Conditions

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Hand Eczema

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

A cluster-randomized clinical trial, including three different hospitals. At each hospital, 78 cleaners will be included.
Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Group 1: Picture-based prevention education and an educational course

The participants will have access to picture-based prevention education, and at the same time, they will participate in an educational course.

Group Type EXPERIMENTAL

Change in the incidence of hand eczema

Intervention Type BEHAVIORAL

Assessed by the self-reported cases of newly-developed hand eczema. Change between baseline and 6 months.

Change in severity of hand eczema

Intervention Type BEHAVIORAL

Assessed by using the Hand Eczema Severity Index (HECSI). HECSI score: 0-360 points (0 best, 360 worst). Change between baseline and 6 months.

Change in the number of self-reported days with absence from work due to having hand eczema

Intervention Type BEHAVIORAL

Self-reported total number of sick days due to having hand eczema. Change between baseline and 6 months.

Change in the number of participants being forced to change their job due to having hand eczema

Intervention Type BEHAVIORAL

Self-reported change of job due to having hand eczema. Change between baseline and 6 months.

Change in The Quality Of Life in in relation to hand eczema

Intervention Type BEHAVIORAL

Assessed by using Hand Eczema Questionnaire (QolHEQ). Change between baseline and 6 months.

Change in the level of knowledge regarding skin care and protection.

Intervention Type BEHAVIORAL

Self-reported level of knowledge regarding skin care and protection. Change between baseline and 6 months.

Group 2: Picture-based prevention education only (no educational course)

The participants will only have access to picture-based prevention education and will not participate in any educational course.

Group Type EXPERIMENTAL

Change in the incidence of hand eczema

Intervention Type BEHAVIORAL

Assessed by the self-reported cases of newly-developed hand eczema. Change between baseline and 6 months.

Change in severity of hand eczema

Intervention Type BEHAVIORAL

Assessed by using the Hand Eczema Severity Index (HECSI). HECSI score: 0-360 points (0 best, 360 worst). Change between baseline and 6 months.

Change in the number of self-reported days with absence from work due to having hand eczema

Intervention Type BEHAVIORAL

Self-reported total number of sick days due to having hand eczema. Change between baseline and 6 months.

Change in the number of participants being forced to change their job due to having hand eczema

Intervention Type BEHAVIORAL

Self-reported change of job due to having hand eczema. Change between baseline and 6 months.

Change in The Quality Of Life in in relation to hand eczema

Intervention Type BEHAVIORAL

Assessed by using Hand Eczema Questionnaire (QolHEQ). Change between baseline and 6 months.

Change in the level of knowledge regarding skin care and protection.

Intervention Type BEHAVIORAL

Self-reported level of knowledge regarding skin care and protection. Change between baseline and 6 months.

Group 3: Placebo (control)

The participants will not have access to picture-based prevention education and do not participate in any educational course.

Group Type PLACEBO_COMPARATOR

Change in the incidence of hand eczema

Intervention Type BEHAVIORAL

Assessed by the self-reported cases of newly-developed hand eczema. Change between baseline and 6 months.

Change in severity of hand eczema

Intervention Type BEHAVIORAL

Assessed by using the Hand Eczema Severity Index (HECSI). HECSI score: 0-360 points (0 best, 360 worst). Change between baseline and 6 months.

Change in the number of self-reported days with absence from work due to having hand eczema

Intervention Type BEHAVIORAL

Self-reported total number of sick days due to having hand eczema. Change between baseline and 6 months.

Change in the number of participants being forced to change their job due to having hand eczema

Intervention Type BEHAVIORAL

Self-reported change of job due to having hand eczema. Change between baseline and 6 months.

Change in The Quality Of Life in in relation to hand eczema

Intervention Type BEHAVIORAL

Assessed by using Hand Eczema Questionnaire (QolHEQ). Change between baseline and 6 months.

Change in the level of knowledge regarding skin care and protection.

Intervention Type BEHAVIORAL

Self-reported level of knowledge regarding skin care and protection. Change between baseline and 6 months.

Interventions

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Change in the incidence of hand eczema

Assessed by the self-reported cases of newly-developed hand eczema. Change between baseline and 6 months.

Intervention Type BEHAVIORAL

Change in severity of hand eczema

Assessed by using the Hand Eczema Severity Index (HECSI). HECSI score: 0-360 points (0 best, 360 worst). Change between baseline and 6 months.

Intervention Type BEHAVIORAL

Change in the number of self-reported days with absence from work due to having hand eczema

Self-reported total number of sick days due to having hand eczema. Change between baseline and 6 months.

Intervention Type BEHAVIORAL

Change in the number of participants being forced to change their job due to having hand eczema

Self-reported change of job due to having hand eczema. Change between baseline and 6 months.

Intervention Type BEHAVIORAL

Change in The Quality Of Life in in relation to hand eczema

Assessed by using Hand Eczema Questionnaire (QolHEQ). Change between baseline and 6 months.

Intervention Type BEHAVIORAL

Change in the level of knowledge regarding skin care and protection.

Self-reported level of knowledge regarding skin care and protection. Change between baseline and 6 months.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Professional hospital cleaners ≥ 18 years old
* Sufficient Danish skills
* Written informed consent

Exclusion Criteria

* Insufficient Danish skills
* Pregnancy
* Other skin diseases on the hands
* Receiving Immunomodulatory therapies
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Copenhagen

OTHER

Sponsor Role collaborator

Danish Working Environment Fund

UNKNOWN

Sponsor Role collaborator

Zealand University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Farnam Barati Sedeh

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kristina Sophie Ibler, M.D.

Role: PRINCIPAL_INVESTIGATOR

Zealand University Hospital

Locations

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Cleaning departments at Køge, Slagelse and Holbæk hospitals

Køge, Region Sjælland, Denmark

Site Status

Countries

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Denmark

Other Identifiers

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20205100702

Identifier Type: -

Identifier Source: org_study_id

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